Effects of rosiglitazone on rabbit atherosclerosis

We sought to validate magnetic resonance imaging(MRI) for documenting the effects of rosiglitazone on rabbit atherosclerosis and the possible mechanism by treatment on the lesions.24 New Zealand white rabbits were randomly divided into normal group, control group and treatment group.After 4 weeks, all rabbits underwent MRI.After examination, the number of circulating endothelial progenitor cells(EPCs) and level of lipid, glucose, nitric oxide(NO) and superoxide anion(O-2·) were measured.MRI demonstrated the regression of atherosclerotic lesions by rosiglitazone which has good correlation with histopathology.Treatment not only increased the level of EPCs and NO, but also raised the ability of inhibition of O2-·.MRI is a promising noninvasive technology to detect the effects of therapeutic interventions.Rosiglitazone slows the progression of atherosclerosis that may in part attribute to its improvement of mobilization of EPCs and the reduced oxidative stress.     

Analysis and improvement of authenticatable ring signcryption scheme

We show that the Zhang-Yang-Zhu-Zhang identity-based authenticatable ring signcryption scheme is not secure against chosen plaintext attacks.Furthermore, we propose an improved scheme that remedies the weakness of the Zhang-Yang-Zhu-Zhang scheme.The improved scheme has shorter ciphertext size than the Zhang-Yang-Zhu-Zhang scheme.We then prove that the improved scheme satisfies confidentiality, unforgeability, anonymity and authenticatability.     

Power network parameter estimation method based on data mining technology

The parameter values which actually change with the circumstances, weather and load level etc.produce great effect to the result of state estimation. A new parameter estimation method based on data mining technology was proposed. The clustering method was used to classify the historical data in supervisory control and data acquisition (SCADA) database as several types. The data processing technology was impliedto treat the isolated point, missing data and yawp data in samples for classified groups. The measurement data which belong to each classification were introduced to the linear regression equation in order to gain the regression coefficient and actual parameters by the least square method. A practical system demonstrates the high correctness, reliability and strong practicability of the proposed method.     

某商用车散热器面罩开裂分析与改进

为解决散热器面罩开裂问题,提出了焊点优化方案和散热器面罩加强板外置/加强板内置方案,并进行了模块化设计,制定了2组改进措施。有限元分析结果表明:2种改进措施与原状态相比,均有良好应力改善效果,满足应力要求。     

蛛网膜下腔出血后内皮素受体(ET_A/ET_B)不平衡表达在大鼠基底动脉痉挛中的作用

目的探讨蛛网膜下腔出血后基底动脉各层中内皮素受体(ETA/ETB)的表达水平变化在血管痉挛(CVS)中的作用机制。方法采用大鼠自体血二次注入枕大池建立SAH后CVS模型,光镜下观察基底动脉形态学变化,并运用免疫荧光染色动态检测ETA/ETB受体表达变化。结果 SAH模型组基底动脉截面积在2d开始下降,到3d时到达最低,以后逐渐恢复至正常。免疫荧光显示SAH后基底动脉内皮细胞层中ETA受体蛋白表达在2d开始增多,3d达高峰,持续到14d,而ETB受体蛋白3d时内皮细胞层中表达显著增多,7d时平滑肌细胞层中表达达高峰,持续到14d。结论两种ETA/ETB受体的差异性表达在SAH后CVS中起重要作用。ETB受体亚型在脑血管各层中具体表达差异有待进一步研究。     

连续刚构桥施工挂篮设计及有限元分析

高墩大跨连续刚构桥主梁箱梁悬臂浇注采用菱形挂篮进行施工,通过建立空间midas有限元模型对挂篮设计时应考虑的混凝土浇注、主构件的强度及稳定性分析、锚固系统、挂篮行走等工况进行计算,为类似施工设计积累经验。     

由船舶响应反推当前海浪频谱的探索研究

借助白噪声谱在数学处理上的独特优势,利用计算流体力学方法(CFD),生成了高精度的白噪声长峰不规则波,实现了船模在该海浪环境下顶浪航行时的纵摇及垂荡耦合运动的数值模拟,从而计算船模纵摇和垂向加速度的响应幅值算子(RAO),达到了由海上实测摇荡时历反推较高精度海浪频谱的目标,并将反推结果与海上实测海浪数据进行了对比,效果良好,从而为在航船舶提供了一种获取当前海浪信息的新方法。     

广东省天然气水运调入需求与码头接卸能力适应性分析

以广东省经济社会发展和全省的能源消耗情况为基础,运用国内生产总值能耗法分析预测广东省未来一段时期的天然气消耗量以及水运调入量,对比广东省沿海现有、拟建的LNG接卸码头通过能力,进行广东省天然气水运调入需求与码头接卸能力适应性分析。     

基于PLC与变频器的船用载货电梯控制系统研究

某型船用载货电梯采用PLC控制。PLC单独使用时,在控制装置在使用过程中存在一些不足,会出现运行不稳定、能耗大、噪音大等问题。通过加装变频器对某型船的PLC单独控制的系统进行系统的升级改造,介绍了基于PLC与变频器的电梯控制系统硬件组成方案及逻辑控制程序。仿真结果表明加装变频器后,电梯故障率降低,提高了电梯运行的安全性和可靠性。