PRELIMINARY STUDY OF OMENTUM TRANSPOSITION TO BRAIN FOR TREATMENT OF ALZHEIMER'S DISEASE

Objective To learn the effect of omemtum transposition to the brain of patients with Alzheimer's disease. Methods Ten consecutive patients, aged 58 - 81 years old, underwent graft of their elongated pedicled omentum onto their left frontal-temperal-parietal cerebral cortex. Those patients, who had more than five years of dementia with low mini mental-state examination (MMSE) scores of 2 -15, were diagnosed by a neurologist. All subjects underwent single photon evoked computer tomography (SPECT) pre- and post-operatively.SPECT results were analyzed semi-quantitatively by calculation of the left/right radioactivity counts symmetry index (Si). The patients were followed up to one year. The outcome was evaluated by the neurologist with a modified scale of activities of daily living (mADL) as well as the MMSE. Results Three months following the surgery,the Si of SPECT increased from ( 98. 7 ± 1.9) % to ( 103. 9 ± 2.3 ) % ( P = 0. 0307). The neurological and neuropsychological testing scores increased insignificantly during the follow-up period. By the one year, the MMSE score rose from 8. 7 ± 1.4 to 10. 7 ± 1.8 ( P ＞ 0. 05 ), while the mADL from 13.3 ± 1.8 to 16. 9 ± 2. 0 ( P ＞ 0. 05 ). One of the patients suffered a heart attack, two had epileptic episodes postoperatively. Conclusion We believe that omental transposition to the brain augments cerebral blood flow, which might be helpful to decelerate the processing of Alzheimer's disease. However, it is still a potentially risky procedure for the elderly.     

改进D-S算法在船舶汽轮机故障诊断中的应用研究

针对汽轮机组的故障特征,将多个传感器获得的实时信号进行特征提取,对D-S证据理论在应用中不合理处进行改进。应用比较的结果表明,改进后的算法公式可信度明显提高,不确定性大大降低。     

人因可靠性分析在铁路安全管理中的运用

现有铁路安全管理的研究与实践,都偏重于提升各项设备的可靠性,而人的可靠性并未得到应有的重视。应引进人因可靠性分析的理论与方法,将人因可靠性分析运用在铁路安全管理中,尤其对关键工种更需进行人因可靠性分析和作业人员应力分析。     

公路桥梁伸缩装置的设计与施工

文章对公路桥梁的伸缩装置的设计计算方法及其选型原则作了叙述,并通过秦皇岛市跨越青龙河桥伸缩缝的施工实例,介绍了GQF型桥梁伸缩装置及其施工工艺。     

基于P3软件的网络计划资源优化方法研究

分析传统工期-资源优化方法的不足,提出应用P3软件进行资源优化,将其运用到船台大合拢分段吊装计划管理中,证实了该软件在资源优化方法上具有一定的多样性和灵活性。     

多媒体网络教学的思考与建议

主要介绍了多媒体网络教学的制约因素,提出了搞好多媒体网络教学的几点建议,并提出对于多媒体网络教学这一现代教学技术应扬其长避其短.     

管道壁厚计算公式改进探讨

通过输油管道及注汽管线壁厚的选择等应用实例来说明传统的管道壁厚的设计公式过于保守,没有相应的壁厚修正标准或公式。这个问题在美国已经得到重视。可参照美国的做法,改进管道壁厚的计算公式,即引入最小壁厚设计因素,完善环向应力公式计算并研究确定管道壁厚与温差之间的关系。     

铁道客车系统的垂向减振分析

建立铁道客车垂向振动系统数学模型,计算客车系统幅频特性曲线,根据曲线峰点来确定系统自振频率,给出客车系统自振频率计算的简单近似解析方法和精确数值方法。提出客车系统各刚体振型共振速度的概念和计算公式,得出共振速度只与系统本身的自振频率和结构参数如车辆定距和转向架固定轴距有关。对客车系统在有无动力吸振器情况下的简谐和随机振动进行分析,认为采用吸振器确实能够在一定程度上抑制车体某些频率成分的振动,适当增大吸振器质量、刚度和阻尼,可以达到较好的减振效果。     

变频调速交流牵引电机绝缘电老化机理的研究

在变频电机绝缘技术研究成果基础上，以动车组变频牵引电机为研究对象，建立电缆和定子绕组高频等效电路模型，研究电机端过电压以及匝间电压分布特性；研制一套基于高压方波脉冲的绝缘老化试验系统，进行牵引电机绕组的绝缘寿命实验，依据介质损耗、局部放电等参量的变化，分析绝缘材料的破坏机理。