Association between the -1562 C/T polymorphism in the MMP-9 promoter and phenotype of esophageal squamous cell carcinoma in northern Chinese population

Objective To conduct a case-control study on the association of the nucleotide polymorphisms in the promoter region of the matrix metalloproteinase-9 (MMP-9) gene with phenotype of esophageal cancer. Methods All subjects were unrelated residents in northern regions of China. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was used to determine the MMP-9 genotypes. Results The overall distribution of genotypes in the patients was not different from that in the controls (OR=0.77, 95% CI=0.45-1.34; P=0.36). There were no significant differences between the patients and the control subjects in terms of the distributions of sex and age, smoking status, alcohol dependence, pickled diet status, or history of environmental exposure. The patients were further examined with stratifications by age, sex, grade, depth of tumor invasion, lymphatic invasion, venous invasion and TNM staging. The results showed no pronounced association among the stratifications. Conclusion There is no significant association between the MMP-9 single nucleotide polymorphism genotypes and phenotype of esophageal cancer.     

基于灰色关联度的客运通道运输方式竞争力研究

运输通道由多种交通方式构成,研究通道内交通方式的竞争力对乘客和运营部门具有重要意义。运用灰色关联度法,以成渝客运通道为研究对象,进行各种交通方式竞争力的演算,并通过与其他方法所研究的结论进行比较分析,证明其合理性与实用性,为相关研究提供参考。     

基于ADAMS与Simulink的汽车ABS控制联合仿真

利用ADAMS/CAR建立整车动力学模型,并在MATLAB/Simulink中设计基于滑移率的ABS模糊控制系统,最后通过ADAMS/Controls接口建立联合仿真模型并仿真.仿真结果表明ABS模糊控制系统在制动过程中取得了很好的防抱死效果,同时也说明了联合仿真在ABS控制系统开发中的可行性.     

基于GA的发动机怠速PID控制优化研究

结合对发动机管理系统中发动机怠速控制系统的研究,分析了数字PID控制的控制原理以及在发动机管理系统上的体现.对于在目标怠速附近的转速波动控制加以探讨,简化控制模型,采用GA算法整定PID控制器中的比例、积分、微分的控制参数,具有模型简单,效率高的优点.同时在车辆上做了实践指导.     

Antibacterial analyse of perovskite

We mainly studied the antibacterial properties of perovskite. Its structure was evaluated by X-ray diffractometer (XRD), scanning electron microscope (SEM), and ultraviolet-visible (UV-vis) absorption spectrometer etc. The antibacterial properties of perovskite to Candida albicans (ATCC10231), Escherichia coli (ATCC25922) and Staphylococcus aureus (ATCC6538) were investigated by the flask oscillation method. The results show that the perovskite has strong antibacterial ability, and continued antibacterial properties; its sterilization rates are 87.00%, 99.50%, 96.22% respectively to these three bacteria.     

构建军民融合式航空战略投送体系

航空战略投送是我军战略投送的重要组成部分,在战争和非战争行动中发挥着举足轻重的作用。军民融合式发展理论是我军军事指导理论的重大创新,已经广泛运用到军事后勤领域的方方面面。论述了军民融合式航空战略投送体系特征、构建军民融合式航空战略投送体系的必然性、构建中国特色军民融合式航空战略投送体系的措施等三个方面,为我军的航空战略投送体系建设提供借鉴。     

高速公路瓶颈区域可变限速控制方法

高速公路交通流处于高峰时,公路主线路段可能出现拥挤的瓶颈路段,导致车辆运行时间增加,路段运行效率降低等问题.本文从高速公路瓶颈区域路段交通流运行的时空特征出发,对现有的Papageorgiou模型进行扩展并考虑速度控制因素,使其适用于可变限速控制环境下的真实交通流运行状态,提出了适用于高速公路瓶颈区域的可变限速控制条件的改进模型,以控制周期内总通行量最大和车辆总行程时间最小为目标,建立高速公路主线可变限速控制优化模型.仿真结果表明,相对于固定限速控制,本文提出的可变限速控制方法可降低总行程时间7.45%,提高平均速度8.78%,表明该可变限速控制模型能在一定程度上缓解高速公路瓶颈区域的拥堵问题.     

Research on Spatially Adaptive High-Order Total Variation Model for Weak Fluorescence Image Restoration

Photoacoustic imaging acquires the absorption contrast of biological tissue with ultrasound resolution. It has been broadly investigated in biomedicine for animal and clinical studies. Recently, a micro-electro-mechanical system (MEMS) scanner has been utilized in photoacoustic imaging systems to enhance their performance and extend the realm of applications. The review provides a recap of recent developments in photoacoustic imaging using MEMS scanner, from instrumentation to applications. The topics include the design of MEMS scanner, its use in photoacoustic microscopy, miniature imaging probes, development of dual-modality systems, as well as cutting-edge bio-imaging studies.     

疏浚抓斗平挖运动研究与仿真

在航道疏浚和大型海洋工程建设的背景下,从现有的传统疏浚技术不能满足市场需求出发,提出抓斗平挖的问题.通过对疏浚抓斗在传统操作方式下挖掘曲线的建立和分析,构建了抓斗的平挖运动数学模型,以抓斗刃口的水平运动为约束条件,反向推导得出抓斗平挖控制策略,并对此控制策略进行了运动学仿真验证.结果表明,疏浚抓斗平挖运动控制策略在抓斗挖泥船的平挖作业上具有有效性及准确性.     

长江中游相对湿度的气候变化特征及其对航运的影响分析

利用1965～2008年长江中游附近17个气象观测站点的相对湿度数据分析了长江中游相对湿度的气候变化特征.分析结果表明:长江中游年平均相对湿度在65％～85％之间,除个别站点外年平均相对湿度以及年高湿日天数均有减小的趋势;大部分站点6～8月份的相对湿度比其他月份要高,且与其他月份相对湿度的差值有增加趋势;高湿日天数在1/3以上,较西的站点7月份高湿日最多,较东的站点3月份高湿日最多;相对湿度与降雨量呈正相关,与蒸发量和日照时间呈负相关.相对湿度的这种变化对粮食、化肥等货物的运输是有利的.