Inhomogeneous cellular automata modeling for mixed traffic with cars and motorcycles

This paper develops inhomogeneous cellular automata models to elucidate the interacting movements of cars and motorcycles in mixed traffic contexts. The car and motorcycle are represented by non‐identical particle sizes that respectively occupy 6×2 and 2×1 cell units, each of which is 1.25×1.25 meters. Based on the field survey, we establish deterministic cellular automata (CA) rules to govern the particle movements in a two‐dimensional space. The instantaneous positions and speeds for all particles are updated in parallel per second accordingly. The deterministic CA models have been validated by another set of field observed data. To account for the deviations of particles' maximum speeds, we further modify the models with stochastic CA rules. The relationships between flow, cell occupancy (a proxy of density) and speed under different traffic mixtures and road (lane) widths are then elaborated.     

Modeling measurement errors and missing initial values in freeway dynamic origin–destination estimation systems

Most existing dynamic origin–destination (O–D) estimation approaches are grounded on the assumption that a reliable initial O–D set is available and traffic volume data from detectors are accurate. However, in most traffic systems, both types of critical information are either not available or subjected to some level of measurement errors such as traffic counts and speed measurement from sensors. To contend with those critical issues, this study presents two robust algorithms, one for estimation of an initial O–D set and the other for tackling the input measurement errors with an extended estimation algorithm. The core concept of the initial O–D estimation algorithm is to decompose the target network in a number of sub-networks based on proposed rules, and then execute the estimation of the initial O–D set iteratively with the observable information at the first time interval. To contend with the inevitable detector measurement error, this study proposes an interval-based estimation algorithm that converts each model input data as an interval with its boundaries being set based on some prior knowledge. The performance of both proposed algorithms has been tested with a simulated system, the I-95 freeway corridor between I-495 and I-695, and the results are quite promising.     

玉蒙铁路曲江峡谷桥位选址及线路方案比选研究

研究目的:结合玉蒙铁路的勘察设计,在地质条件极为复杂的山区峡谷河段,进行重点桥位及线路走向的多方案工程地质条件研究比选,确定合理的桥址及线路方案。研究方法:遵循“线路服从桥位,桥位服从地质选址”的原则。采用地质综合勘探方法,详细查明峡谷区重大工程地质问题,综合比选确定桥址及线路方案。研究结果:作者通过系统的地质研究和对该项目地质选线经验的总结,提出了“复杂地质环境条件下必须坚持重大工程优先选址,并重视宏观区域地质选线”的原则及勘察设计中应注意的问题,最终选定了工程地质条件相对较好的桥址及线路方案。研究结论:玉蒙铁路经过的曲江峡谷地段,地处高烈度地震区、活动断裂带附近,内外动力地质灾害突出,使重大控制工程曲江大桥桥位的选择十分困难。工程技术人员通过系统研究峡谷区的区域地质环境及主要的工程地质问题,比选了8个桥址及4个线路方案,最终选定了5号桥址的C2K线路方案,为工程设计与施工创造了有利条件。     

提高探地雷达超前地质预报精度的方法研究

研究目的：在对复杂多变地质条件下的地下隧洞进行施工时，进一步提高喀斯特岩溶多变地质中地质超前预报的精度，使施工顺利开展。 研究方法：通过对黔桂铁路扩能改造工程隧道群施工中应用探地雷达技术对掌子面前方不良地质体的预测预报实践探索，围绕关键技术问题展开研究。 研究结果：结合现场实际提出了改良优化检测方法与工艺、建立预报及预警体系、多种预测分析相互核检滤差、引入数码影像三维预测等综合预报方法的见解并通过实践检验。 研究结论：该方法有效提高了探地雷达在喀斯特岩溶地质中对不良地质体探测预报的精确度和分析描述的准确性。     

The experimental observation on the repairing spinal cord injury by olfactory ensheathing cells allograft of different sources

Objecttive To observe the repaired effect of distinct source olfactory ensheathing cells （OECs） on spinal cord injury （SCI） rats. Methods These OECs were dissociated from olfactory bulb and olfactory mucosa of SD rats and transplanted to the injuried region of spinal cord injury rats. The function of nerve, motor evoked potential of hind legs and the histopathlogical diversities of injuried spinal cord were observed. Results The OECs grafts into the SCI area could survive longer time. The BBB scale, incubation stage of EP and histopathologic manifestations showed that the group with transplanted OECs regained more improvement in hindlimb than the control group. Conclusion The OECs of two sources have the same ability to regain and improve the axonal function which can promote axons regeneration of SCI.     

经颈静脉肝内门腔静脉内支架分流术治疗门脉高压症5例报告

采用经颈静脉肝内门腔静脉内支架分流术（Ｔｒａｎｓｊｕｇｕｌａｒｉｎｔｒａｈｅｐａｔｉｃｐｏｒｔｏｓｙｓｔｅｍｉｃｓｔｅｎｔｓｈｕｎｔ，ＴＩＰＳＳ）治疗门脉高压症５例，全部成功。分流后门脉压从术前（３．９０±０．７０）ｋＰａ降至（２．３６±０．３６）ｋＰａ；食管、胃底静脉曲张及胸、腹水明显减轻。术后并发症与肝血流、门静脉主干血流速度变化有关。结果表明，ＴＩＰＳＳ易成功，创伤小，并发症轻，降低门静脉压可靠；肝血流监测、抗凝、抗肝昏迷可提高疗效。     

外源性p16基因对肾癌细胞周期及体外增殖的影响

目的　观察外源性 p16基因对肾癌细胞周期的影响及其对肾癌细胞的生长抑制作用。方法　利用携带人 p16基因的真核表达载体,采用脂质体介导法将其导入人肾癌细胞系 GRC- 1 中,观察其对瘤细胞的作用。结果　①免疫组织化学方法检测显示转染 p16基因的GRC 1细胞可显著表达 p16蛋白。②流式细胞仪检测证明,外源性 p16 基因可在肾癌细胞周期G1期到S期发挥抑制作用。③与对照组相比,转染 p16 基因的 GRC- 1 细胞生长明显受到抑制。结论　外源性 p16基因具有细胞周期特异性地抑制肾癌细胞生长的作用。     

PRIMARY STUDY ON MECHANISM OF COLLAGEN SYNTHESIS INHIBITION IN CULTURED HUMAN FETAL HEPATOCYTES PRETREATED BY SALVIA MILTIORRHIZA BUNGE

Ithasbeenclearedthatreactiveoxygenspeciesandreactiveoxygenspecies inducedlipidperoxida tioncanstimulatecollagensynthesisofhepaticparenchymalcellsandnonparenchymalcellsandre sultinhepaticfibrosis,andthecollagensynthesisincreasingofHepatocytesmay playanimportantroleinhepaticfibrosis[1 -5] .Wehavefoundthatsalviamiltiorrhizabunge (SMB)couldprotecthu manfetalhepatocytesfromcarbontetrachloride(CCl4)mediatedlipid peroxidationinjuryinvit ro[6] .However,theeffectofSMBoncollagensyn thesisofhumanhepat…     

基于伙伴选择和生产分销计划的供应链网络设计

设计供应链网络主要考虑满足外部客户需求最大化和网络总体效用的最大化,其目的是寻求合适的合作伙伴,从而制定符合实际的生产分销策略.为了解决复杂供应链网络设计的问题,提出了一种新的多阶段数学算法模型,该方法是基于遗传算法、层次分析法、多属性效用理论、以同时满足供应商和客户在网络各个层级上的需求.最后,应用该方法很好地解决了所列举的案例,并证明该方法的有效性和实用性.     

C反应蛋白与高血压病、冠心病关系的临床研究

目的分析高血压病、冠心病患者血清C反应蛋白(CRP)的变化及其与相关临床指标的关系。方法测定143例高血压病、108例冠心病患者和120例健康体检者的血清CRP、空腹血糖(FBG)、血脂及体积指数(BMI)并做相关分析。结果高血压和冠心病组CRP水平显著高于正常对照组(P<0.01);高血压1级与3级间CRP差异有显著性(P<0.05);急性心肌梗死(AMI)组与不稳定型心绞痛(UAP)组CRP高于稳定型心绞痛(SAP)组,差异有显著性(P<0.05);CRP与年龄、TG、FBG呈显著正相关,与HDL-C呈显著负相关(P<0.05)。结论①CRP是炎症标志物,高血压与冠心病患者血清CRP显著升高,提示患者体内存在炎症反应;②CRP水平反映了高血压和冠心病患者的病变程度。