Radiosensitivity of β-elemene on rabbit VX2 renal transplant carcinoma model

Objective To investigate the effects of low dosage ofβ-elemene on the radiosensitivity of rabbit VX2 renal transplant carcinoma model. Methods We took the rabbit VX2 renal transplant carcinoma as the model. Experimental rabbits were divided into three groups： the control group, the radiation group, and the radiation ＋β-elemene （radiosensitivity） group. The change of tumor was observed by Spiral CT and B ultrasound to compare its regrowth period. The tumor was measured by light microscopy and electron microscopy. Results The tumor in radiosensitivity group was restrained obviously and the sensitization enhancement ratio （SER） of β-elemene was 1.89. Different apoptosis was observed under transmission electron microscopy. Conclusion Low dosage β-elemene can enhance the radiosensitivity of rabbit VX2 renal transplant carcinoma model and induce the apoptosis of tumor cells, but the mechanism needs further study. It promotes apoptosis in mechanisms in vitro.     

适应铁路提速需求推进交通动员发展

铁路提速对我国国防交通动员带来了深刻影响:对铁路动员信息化建设、优化国防交通运输格局、提高铁路快速动员能力和加快专业技术队伍建设等提出了新的要求,应充分发挥动员潜力,全面加强铁路动员指挥网络、铁路军运衔接工程、运输人才队伍和运输保障队伍等方面的建设,完善铁路运输军代体系等运行机制,提升铁路运输动员综合效能。     

农村客运站建设与管理模式的创新

针对目前农村客运站建设与管理中存在的客运站点建设跟不上发展、客运市场经营主体混乱等问题,提出合理安排农村客运站点布局的原则以及"站所合一"、"三定四统一"等管理模式,以扭转农村客运市场的混乱局面。     

角膜基质脱细胞处理与相容性实验研究

目的寻找有效适宜的脱细胞方法对猪角膜进行处理,制备角膜生物支架材料。方法利用胰酶和胶原酶消化结合液氮冻融的方法对猪角膜基质进行处理,60Co消毒,冻干保存。经组织学观察、细胞培养附和与动物移植检验其生物特性。结果获得的脱细胞角膜基质,显微结构观察显示板层结构完整,胶原纤维间组织结构疏松,未见细胞残留,整个基质成网状结构,在上皮面保存有完整连续的基底膜。细胞培养附和实验观察到种子细胞可以在基质上良好生长。动物移植实验未见明显的炎症反应与排斥。结论经该法脱细胞处理后得到的角膜基质无细胞毒性,组织相容性好,可以成为适宜的组织工程支架材料。     

高速船舶操纵及碰撞危险分析

内河航运船舶正向高速化、大型化发展,为正确判断内河船舶航行所面临的碰撞危险,减少因人为失误引起的内河船舶碰撞事故,通过对高速船舶操纵性及受内河航道限制影响的船舶碰撞危险进行分析,建立内河船舶碰撞危险综合评判模型,并运用模糊理论方法对船舶碰撞危险进行综合评判.仿真结果表明,采用所提出的模型对内河船舶碰撞危险进行评判,较好地反映了内河船舶碰撞危险的实际情况.     

Effects of erigeron breviscapus （Vant.） Hand-Mazz pretreatment on pathology and oxyradical level following spinal cord ischemia-reperfusion injury in rabbits

Objective To investigate the effects of erigeron breviscapus (Vant.) Hand-Mazz (erigeron breviscapus) pretreatment on pathology and oxyradical level in the spinal cord after ischemia-reperfusion (I/R) injury in rabbits. Methods A total of 40 New Zealand white rabbits were randomly divided into three groups: sham-operation group with 10 rabbits treated with only abdominal aorta exposure without occlusion, control group with 15 rabbits that underwent ischemia for 50 minutes and treated with matched saline, and experimental group with 15 rabbits that underwent ischemia for 50 minutes and treated with erigeron breviscapus (9mg/kg) injection before ischemia. Malondialdehyde (MDA) level and superoxide dismutase (SOD) activity in the spinal cord were examined at 6 and 24 hours after I/R, respectively. The morphological changes and the number of the spinal cord anterior horn motor neurons were observed and counted under the light microscope and electron microscope, respectively. Results The level of MDA was markedly decreased and SOD activity was increased in the experimental group compared with those in the control group (P<0.01). Compared with that in the control group, the number of motor neurons in the experimental group significantly increased at 24h after I/R (P<0.01) and the morphous of the motor neurons improved. Conclusion Erigeron breviscapus can reduce oxyradical production and the apoptosis of nerve cells, and protect nerve tissue structure and function after spinal cord I/R.     

大跨径连续刚构桥施工监控技术

为了保障施工过程的安全,在文昌大桥的施工过程中,在主桥控制截面布设了应变计,对施工过程中结构的应力变化进行跟踪监测,为桥梁施工提供安全预警;为了保证成桥线形满足设计要求,对悬浇过程中的主梁挠度进行跟踪监测与控制,为施工提供立模标高,并通过合理设置预拱度来控制梁体线形。     

基于可变公交发车频率的城市拥挤道路收费定价优化

考虑城市路网中不同出行方式车流之间相互影响,通过对私家车实行拥挤道路使用收费和增加公交发车频率之间的相互制约关系分析,提出了基于可变公交发车频率的城市拥挤道路收费定价的优化问题. 在分析确定路网上公交车和私家车出行方式的广义出行成本的基础上建立了该问题的双层规划模型,其中上层规划以路网上的出行者消费盈余最大为优化目标,下层规划为弹性需求下的组合出行网络用户平衡模型;并设计了基于模拟退火算法求解的优化算法. 算例分析表明,基于可变公交发车频率的城市拥挤道路收费定价模型和算法能够更有效地解决道路拥挤问题.     

VW-MSPC方法在变压器状态评估中的应用研究

针对变压器状态评估变量指标之间具有相关性以及重要性不同的特点,在基于马氏距离的传统多元统计控制图中引入加权马氏距离,设计一种基于变量加权的多元统计过程控制的变压器评估方法。该方法结合关联规则方法给出的变压器关键指标变量体系利用多元控制图的波动检出能力,将变压器各类故障对应的多元实时监测数据转化为一个检验统计量,进而对变压器运行状态进行评估。电流回路过热故障的实例分析表明,相对于现行的变压器状态评估标准,该方法具有更快的故障检出速度;对于已知故障的样本数据的回顾检测表明该方法具有较高的故障检出率。     

感应加热电源并联控制系统的通信设计与实现

基于西门子S7-200 SMART PLC和DSP处理器,设计了感应加热电源并联控制系统,建立了DSP和PLC之间、PLC与触摸屏HMI之间的通信协议并编写程序,实现了DSP与PLC之间的数据传输。实际应用表明:该系统通信效果良好,具有较强的实用价值。