EXPRESSION OF HUMAN RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST (rhIL-1ra) IN E.COLI

ThisprojectissupportedbyChineseMedicalBoard(U.S.A)In1990,EisenbergisolatedacDNAfromthehumanmonocytelibrary,expressionofthecDNAinE.coltyieldedtheproteinthatcouldhinderIL--lbindingIL--lreceptor,hetermedtheproteininterleukin--1receptorantagonist(IL--lra)ti.23.IL--lraisauniquecytokinethatcanstronglybindthecellsurfacereceptorsofIL--Iwithoutinducinganydetectableintracellularresponses"'.SinceitisaneffectivecompetitiveinhibitorofIL--lbothinvitroandinvivot'3,IL--lraisausefultooltodetermineth…     

扁板侧胀试验在高速铁路软土地基勘察中的应用研究

扁板侧胀试验(DMT)是兼具旁压试验和静力触探双重功能的原位测试技术。在京沪高速铁路昆山试验段的软土地基勘察中应用了该项技术,并与其他测试手段和土工试验成果进行对比分析。试验表明,扁板侧胀试验在软土地基勘察方面具有独特优势。     

客运专线轨道检测及维修技术的分析探讨

主要介绍轨道检测及维修技术在保持客运专线轨道平顺状态中的重要性、国内现有轨检技术的优缺点及发展趋势、轨道维修的内容及方法等。     

客运专线建设中的物资成本核算

工程项目如何建立适应施工企业自身特点的物资成本核算方式仍在探索中.通过石太客运专线工程的物资成本核算管理形势分析,就物资成本核算管理模式作一些探讨.     

大跨度连续梁支座布置对桥上无缝线路钢轨附加力的影响分析

桥梁的温度跨度是影响桥上无缝线路附加力的最重要的因素之一,合理的布置桥梁支座可以有效地减小钢轨伸缩力。综合考虑钢轨、轨枕、扣件、道床及梁跨结构相互作用,建立了连续梁桥上无缝线路梁-轨相互作用模型,重点分析了桥梁支座布置对钢轨伸缩力的影响,通过计算,优化桥梁支座布置形式,减小了钢轨附加力,对桥上无缝线路的设计有一定的指导意义。     

牵引变压器差动保护装置误动作统计与对策

牵引变压器是牵引供电系统中重要的电气设备,它的安全运行直接关系到电气化铁道安全稳定的工作.本文在对牵引变压器差动保护误动作行为统计分析的基础上,总结差动保护装置误动作跳闸的原因,并提出了相应的解决对策.     

Analysis of the optimal length of road expansion – A case study of the Taipei metropolitan area

This study explores the optimal investment in the length of an expanded section of road to mitigate the congestion on a transportation corridor. It is assumed that one end of the road is in the central business district (CBD) and that the households are uniformly distributed along the road. Each individual makes trips from his/her residence to the CBD. Trip demand is elastic and depends on the cost of the trip (including congestion costs). During the first stage, the government determines the length of the expanded section given the width of that section. In the second stage, road users determine their trip demands by taking into consideration the trip cost function. In the process of solving this problem, the equilibrium traffic volume is first solved using differential equations. The optimal length of the expanded section is then solved by maximizing the social welfare. The analysis is then applied to the case of the Tucheng city – Banciao city – Taipei CBD corridor in the Taipei metropolitan area. The scheme of road expansion without tolling performs closely to the first-best scheme for the case of a high potential demand. This study’s approach can serve as valuable reference for city planners engaged in road planning in a transportation corridor between the CBD and satellite cities in a metropolitan area.     

Evaluating parking reservation policy in urban areas: An environmental perspective

This paper investigates a parking reservation mechanism to reduce car cruising to find parking. To consider the benefits for drivers and parking facility providers, we charge drivers for making reservations in addition to parking fees, by introducing a reservation pricing model that makes reservation prices equivalent to the value of saved search time. By modeling the number of vacant spaces as a stochastic variable, and applying binomial pricing methods, parking reservation prices are obtained. Numerical examples based on the data for two parking facilities in Taiwan are given.     

Allocation flexibility and price efficiency within Singapore’s Vehicle Quota System

Permit or license plate quotas are highly effective albeit controversial policy tools for managing growth in the vehicle population and thereby, adverse traffic congestion. A judicious distribution of the scarce permits that targets the dual objectives of price efficiency and social diversity in vehicle ownership can however mitigate the controversy. This paper scrutinizes the attainment levels of these two objectives within Singapore’s multi-categorical Vehicle Quota System in two time periods (1991–1998 and 2002–2011) which differ in the number of permit allocation categories, the auction format used (sealed versus open bids) and in the frequency of distribution (monthly versus semimonthly). The lessons derived are contrasted to the other two jurisdictions which have also implemented quotas on their vehicle registrations namely, Shanghai and Beijing.     

Aggregates cranes handling capacity of container terminals: the port of Kaohsiung

This study looks at the degrees of interference for multiple cranes that work simultaneously at six major container terminals in the port of Kaohsiung. The results confirm that there are different degrees of mutual crane interference among terminals where different operational modes are adapted in the container yards. RTG handling systems show a very high value of aggregate cranes exponent f, with nearly no interference, as long as the number of allocated cranes is no more than the number of truck lanes under each crane. While SC systems reveal a relatively larger degree of mutual interference as the number of cranes increase.