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171.
Objective To explore the risk association of ABCA1-V771M polymorphism with coronary heart disease (CHD) in Hart nationality in Northwest of China. Methods With case-control study, ABCA1-V771M polymorphism was detected in 204 unrelated Hart nationality people in Northwest of China, and all the subjects by coronary angiography were grouped into 106 cases and 98 controls. The genotypes and alleles frequency distribution of ABCA1-V771M polymorphisms were analyzed by PCR-RFLP analysis, and the clinical statistics of serum lipids were compared and its effects of ABCA1-V771M polymorphism on the plasma lipid levels and coronary atherosclerotic heart disease were analyzed. Results The genotypic frequencies of ABCA1-V771M polymorphism matched well under Hardy-Weinberg equilibrium (P>0.05), V and M allelic frequencies were 33.3% and 66.7%. In comparison with VV VM genotype carriers, MM genotypes carriers had much lower plasma levels of HDL-C (P<0. 001) and much higher plasma levels of TG (P<0. 05). M allelic frequency in CHD group was significantly higher than V allelic frequency (P<0. 05). M allele was related with more severity of atherosclerosis in the coronary artery than V allele (P<0.05). However, there was no obvious difference in the incidence of AMI among carriers with three genotypes of ABCA1-V771M polymorphism (P>0.05). Conclusion ABCA1-V771M polymorphism was not only associated with the plasma levels of HDL-C and TG, but also related to the susceptibility and severity of coronary atheroselerotic heart disease. Moreover, M771 allele appeared to be atherogenie among Han population in Northwest of China. 相似文献
172.
杨娥 《广州航海高等专科学校学报》2015,(1):28-30
沥青玛蹄脂混合料作为良好的钢桥面铺装层材料,其高温性能一直是关注的焦点,本文基于室内车辙试验研究了其高温性能影响因素,重点分析了荷载和温度、拌合时间及加铺SMA对沥青玛蹄脂混合料的高温性能指标动稳定度的影响规律,为今后玛蹄脂混合料的路用实践提供了借鉴. 相似文献
173.
174.
Konstantin I.Matveev Nicholaus I.Perry Alexander W.Mattson Christopher S.Chaney 《船舶与海洋工程学报》2015,(1):25-29
This paper addresses the development and testing of a remotely controlled boat platform with an innovative air-ventilated hull. The application of air cavities on the underside of ship hulls is a promising means for reducing hydrodynamic drag and pollutant emissions and increasing marine transportation efficiency. Despite this concept’s potential, design optimization and high-performance operation of novel air-cavity ships remain a challenging problem. Hull construction and sensor instrumentation of the model-scale air-cavity boat is described in the paper. The modular structure of the hull allows for easy modifications, and an electric propulsion unit enables self-propelled operation. The boat is controlled remotely via a radio transmission system. Results of initial tests are reported, including thrust, speed, and airflow rate in several loading conditions. The constructed platform can be used for optimizing air-cavity systems and testing other innovative hull designs. This system can be also developed into a high-performance unmanned boat. 相似文献
175.
A panel method is described for calculating potential flow around near-surface submarines. The method uses Havelock sources which automatically satisfy the linearized free-surface boundary condition. Outputs from the method include pressure field, pressure drag, wave resistance, vertical force, trim moment and wave pattern. Comparisons are made with model tests for wave resistance of Series 58 and DARPA SUBOFF hulls, as well as with wave resistance, lift force and trim moment of three length-to-diameter variants of the DSTO Joubert submarine hull. It is found that the Havelock source panel method is capable of determining with reasonable accuracy wave resistance, vertical force and trim moment for submarine hulls. Further experimental data are required in order to assess the accuracy of the method for pressure field and wave pattern prediction. The method is implemented in the computer code “HullWave” and offers potential advantages over RANS-CFD codes in terms of speed, simplicity and robustness. 相似文献
176.
The scale effect leads to large discrepancies between the wake fields of model-scale and actual ships, and causes differences in cavitation performance and exciting forces tests in predicting the performance of actual ships. Therefore, when test data from ship models are directly applied to predict the performance of actual ships, test results must be subjected to empirical corrections. This study proposes a method for the reverse design of the hull model. Compared to a geometrically similar hull model, the wake field generated by the modified model is closer to that of an actual ship. A non- geometrically similar model of a Korean Research Institute of Ship and Ocean Engineering (KRISO)’s container ship (KCS) was designed. Numerical simulations were performed using this model, and its results were compared with full-scale calculation results. The deformation method of getting the wake field of full-scale ships by the non-geometrically similar model is applied to the KCS successfully. 相似文献
177.
In this paper, vibration characteristics of the structure in the finite fluid domain are analyzed using a coupled finite element method. The added mass matrix is calculated with finite element method (FEM) by 8-node acoustic fluid elements. Vibration characteristics of the structure in finite fluid domain are calculated combining structure FEM mass matrix. By writing the relevant programs, numerical analysis on vibration characteristics of a submerged cantilever rectangular plate in finite fluid domain and loaded ship model is performed. A modal identification experiment for the loaded ship model in air and in water is conducted and the experiment results verify the reliability of the numerical analysis. The numerical method can be used for further research on vibration characteristics and acoustic radiation problems of the structure in the finite fluid domain. 相似文献
178.
To deal with the effect of compressible fluids on the supercavitating flow over the subsonic disk cavitator of a projectile, a finite volume method is formulated based on the ideal compressible potential theory. By using the continuity equation and Tait state equation as well as Riabouchinsky closure model, an “inverse problem” solution is presented for the supercavitating flow. According to the impenetrable condition on the surface of supercavity, a new iterative method for the supercavity shape is designed to deal with the effect of compressibility on the supercavity shape, pressure drag coefficient and density field. By this method, the very low cavitation number can be computed. The calculated results agree well with the experimental data and empirical formula. At the subsonic condition, the fluid compressibility will make supercavity length and radius increase. The supercavity expands, but remains spheroid. The effect on the first 1/3 part of supercavity is not obvious. The drag coefficient of projectile increases as the cavitation number or Mach number increases. With Mach number increasing, the compressibility is more and more significant. The compressibility must be considered as far as the accurate calculation of supercavitating flow is concerned. 相似文献
179.
使用有限元分析以改善重载运输车轴 总被引:1,自引:0,他引:1
分析了北美铁路货运发生的车轴故障,介绍了使用有限元对F级和K级车轴进行应力分析计算,研究车轴尺寸变化对应力的影响,并提出了改善重载车轴设计的建议. 相似文献
180.
LI Tie-shan YAN Shu-jia and QIAO Wen-ming . School of Naval Architecture Ocean Civil Engineering Shanghai Jiao Tong University Shanghai China . Navigation College Dalian Maritime University Dalian China . Navigation School Shandong Jiaotong College Weihai China 《船舶与海洋工程学报》2007,6(4)
This paper focuses on the problem of linear track keeping for marine surface vessels. The influence exerted by sea currents on the kinematic equation of ships is considered first. The input-to-state stability(ISS) theory used to verify the system is input-to-state stable. Combining the Nussbaum gain with backstepping techniques,a robust adaptive fuzzy algorithm is presented by employing fuzzy systems as an approximator for unknown nonlinearities in the system. It is proved that the proposed algorithm that guarantees all signals in the closed-loop system are ultimately bounded. Consequently,a ship's linear track-keeping control can be implemented. Simulation results using Dalian Maritime University's ocean-going training ship 'YULONG' are presented to validate the effectiveness of the proposed algorithm. 相似文献