消旋四氢巴马汀在兔体内的药动学和药效学研究

观察了消旋四氢巴马汀静脉注射对在体家兔希氏束电图的影响 ,在获取效应指标的同时布点采血 ,用高效液相色谱法测定血药浓度 ,以探讨消旋四氢巴马汀效应动力学及其随血药浓度的经时变化规律。结果表明用药后 A- H间期明显延长 ,且呈剂量依赖性 ,效应的变化与浓度的变化呈线性正相关 ( r大 =0 .95 6 3,r小 =0 .9473) ,与对照组比较有显著性差异 ( P <0 .0 5 ) ,用药后 H- V间期无变化。提示消旋四氢巴马汀静脉制剂可能适用于中止阵发性室上性心动过速。     

沪宁高速公路安全体系和中分带开口护栏研究

针对扩建后8车道沪宁高速公路的交通安全问题提出了“基于交通行为模式推断的多元回归事故预测模型”,并在事故预测的基础上对未来8车道的沪宁高速公路进行了安全评价。事故预测和安全评价结果可对扩建的沪宁高速公路交通工程设置方案进行指导。本文还根据沪宁高速公路的实际情况,从乘客及驾驶员的安全性和舒适性入手,采用计算机模拟及实车试验的研究方法,提出了适用于沪宁高速公路的中央分隔带开口长度,单侧车道封闭时开口处的交通组织及适用于开口处的混凝土活动护栏。     

矩形断面综合管廊线缆舱通风阻力系数数值仿真研究

为探究城市综合管廊通风阻力影响因素和计算方法,通过调研综合管廊通风系统设计和交通隧道通风阻力的相关研究成果,得到综合管廊线缆舱单位长度通风阻力系数的计算公式。建立综合管廊线缆舱三维数值模型,利用ANSYS FLUENT软件并采用标准双方程模型对通风障碍物比例约为15%的综合管廊线缆舱室内部支架、线缆和热效应对通风的阻力影响进行模拟。分析得到： 1)相较于内部无支架、线缆的综合管廊线缆舱,有支架、线缆时对通风阻力影响极大; 2）随着通风风速的增大,综合管廊线缆舱通风阻力逐渐增大,而通风阻力系数减小,且逐渐趋于稳定; 3）进口空气温度、线缆发热及舱内温度产生的热效应对通风的阻力效应有一定的影响,且随着进风温度增大,通风阻力和通风阻力系数逐渐降低。     

米仓山隧道深大竖井建井新法

为解决目前公路行业面临的大直径竖井建设缺乏相关规范支撑和竖井主要采用复合式衬砌及单行掘砌作业带来的工序复杂、建井速度慢、缺乏相应施工机械配套和安全性较差等难题,通过吸收煤矿深大竖井主流支护与掘砌技术,结合公路运营情况考虑送风井与排风井分设或通过中隔墙合设的布置方式,在公路行业现有支护与掘砌技术的基础上,对米仓山隧道通风竖井进行多方案研究,最终选定单层模筑混凝土衬砌与短段掘砌混合作业单井布置方案,并采用该方案安全快速地建成净直径9 m、深431.8 m的深大竖井。工程实践表明： 1)在同等通风面积下双井工程量要小于单井工程量,但由于其配套施工设备造价高,单井造价要低于双井造价; 2)单层模筑混凝土衬砌与短段掘砌混合作业方式在进度和施工安全等方面优于复合式衬砌及掘砌单行作业方式,可作为公路深大竖井建井新方法。研究结果可为今后深大竖井的修建提供技术支撑和为规范的修订积累经验。     

Are AIS-based trade volume estimates reliable? The case of crude oil exports

Most global trade statistics in the public domain refer to official customs data, which are not generally available on a micro (individual cargo) level. With the increasing availability and completeness of ship positioning data from the global Automated Identification System (AIS), it is possible to derive more timely and detailed trade statistics for homogeneous commodity groups. The objective of this article is twofold: (1) to compare the accuracy of AIS-derived trade statistics to official customs data in the crude oil market and (2) to add a breakdown of trade by vessel size over time. We find that while AIS-derived data for seaborne crude exports show good alignment with official export numbers in aggregate, there are substantial temporal and geographical differences across countries and time due to the use of pipelines and transshipment in parts of the supply chain. We highlight the challenges in properly structuring and aggregating micro-level cargo data. Our findings are important for the proper derivation of shipping demand from trade data.     

Norwegian port connectivity and its policy implications

The importance of a seaport depends on how well it is connected in a transportation network. A port’s connectivity is therefore one of the key issues in determining its competitiveness and developments in regions and countries. We construct a port connectivity index for major Norwegian ports based on a unique dataset derived from the automated identification system (AIS) for multiple vessel types over a 7-year period. Port connectivity is evaluated empirically by the number of unique vessel visits, vessel sizes, and cargo sizes. The research has implications for port authorities and policy makers in the areas of port planning, infrastructure investment, short sea shipping promotion, and environmental policies. The contributions of this research are twofold. First, the methodology linking the AIS vessel-tracking system with port connectivity is a pioneering empirical application of maritime big data. Second, the port connectivity index is constructed for multiple vessel types and regional port groups, which is an improvement from the current literature where conceptual measures are constructed based on hypothetical and usually too simple optimization rules. The methodology can be easily expanded to other regions in the world.     

船用低压大功率AFE推进变频器的研究

本文通过主回路、硬件电路、软件控制算法和水冷散热几个方面对船用低压有源前端推进变频器进行了较为详细的理论介绍,针对船用设备对体积、重量和散热等方面的特殊要求进行了工程实现的有效探索,最后通过仿真与试验验证了设计理论的正确性与工程化的可实现性。     

乘用车燃料消耗量标准推进中国节能与新能源汽车的发展

随着我国汽车保有量的不断攀升,环境污染和能源安全问题日益严重。节能减排势在必行,汽车作为国民经济的支柱产业责无旁贷。乘用车燃料消耗量第四阶段标准的颁布实施,将促使企业探索节能途径,促进我国汽车产业的转型升级,推进节能与新能源汽车产业的发展。     

论科层理论视角下的企业内部控制

基于对企业内部控制系统是开放理性系统的认识,本文借鉴组织经济学与组织行为学的相关理论,通过对内部控制与科层理论一致性与相容性的论证分析,从组织科层理论的角度构建分别以股东、经营者、管理者以及员工为主体的四层次内部控制框架及其整体性制度安排,针对科层体制自身存在的局限性,提出完善四层次内部控制框架的若干对策.     

500t长大舱口货驳事故原因分析

介绍了500 t长大舱口货驳沉没的情况,分析了该船的基本技术状况,对船体结构强度进行了校核。