Effect of ABCA1-V771M polymorphism on plasma lipid levels and its relationship with coronary atherosclerotic heart disease

Objective To explore the risk association of ABCA1-V771M polymorphism with coronary heart disease (CHD) in Hart nationality in Northwest of China. Methods With case-control study, ABCA1-V771M polymorphism was detected in 204 unrelated Hart nationality people in Northwest of China, and all the subjects by coronary angiography were grouped into 106 cases and 98 controls. The genotypes and alleles frequency distribution of ABCA1-V771M polymorphisms were analyzed by PCR-RFLP analysis, and the clinical statistics of serum lipids were compared and its effects of ABCA1-V771M polymorphism on the plasma lipid levels and coronary atherosclerotic heart disease were analyzed. Results The genotypic frequencies of ABCA1-V771M polymorphism matched well under Hardy-Weinberg equilibrium (P>0.05), V and M allelic frequencies were 33.3% and 66.7%. In comparison with VV VM genotype carriers, MM genotypes carriers had much lower plasma levels of HDL-C (P<0. 001) and much higher plasma levels of TG (P<0. 05). M allelic frequency in CHD group was significantly higher than V allelic frequency (P<0. 05). M allele was related with more severity of atherosclerosis in the coronary artery than V allele (P<0.05). However, there was no obvious difference in the incidence of AMI among carriers with three genotypes of ABCA1-V771M polymorphism (P>0.05). Conclusion ABCA1-V771M polymorphism was not only associated with the plasma levels of HDL-C and TG, but also related to the susceptibility and severity of coronary atheroselerotic heart disease. Moreover, M771 allele appeared to be atherogenie among Han population in Northwest of China.     

自行车流视频识别判断方法研究

考虑算法的实时性,交通流个体识别往往采用轮廓特征来描述。由于自行车与行人的很多轮廓特征值相近,在复杂城市交通环境中,从慢行交通流中准确地识别出自行车是目前采用视频检测交通流的难点之一。通过现场视频检测获取足够的样本外轮廓数据,分析检测目标轮廓的高、宽、高宽比、面积等典型轮廓特征,发现目标轮廓高宽比特征能较好地识别出行人、自行车等慢行交通,并给出合适的取值范围。研究表明自行车高宽比能够较好地成为视频识别的依据,为自行车视频识别提供数据。     

甘泉铁路区间通过能力研究

阐述甘泉铁路车站分布和运量发展情况及货运量增加后区间通过能力不足的问题,介绍甘泉铁路行车组织和区间通过能力计算方法,计算各区间的通过能力,结合近期货物运量500万t、700万t、1000万t三种情况,计算需求通过能力,并给出提高通过能力的具体方案,为下一步货运量的增加做准备。     

科考船多波束导流罩线型CFD分析方法与试验验证

针对于科考船多波束导流罩设计和船体线型设计缺少关联分析的主要问题,介绍了一种科考船导流罩线型与船体线型一体化CFD分析方法,综合考虑实船航行过程中船体型线和导流罩型线之间的相互影响。根据这种分析方法,分别对导流罩和船体组合线型的阻力性能和防气泡性能进行了CFD预报,并进行了船模试验。两者吻合良好,验证了此种CFD分析方法的工程实用性。     

Marine accident analysis for collision and grounding in oil tanker using FTA method

In this study, collision and grounding data registered in GISIS (Global Integrated Shipping Information System) were investigated for oil tankers. The database includes the information of the collision and grounding accidents during the period between 1998 and 2010 in oil tankers. The risk assessments were carried out using fault tree analysis (FTA) programme for the incidents as collision and grounding occurred in oil tankers. In this study, we were able to investigate first the potential problems which cause the collision and grounding accidents have been determined, second, the occurrence of accidents has been shown with causal factors by the FTA method, and, finally, the significance degree of the initial events causing occurrence of accidents have been put forth. Collision in oil tanker resulted in economical loss (81%), pollution (6%) and death or injury (13%). Grounding in oil tanker resulted in economical loss (91%) and pollution (9%). According to the FTA results, the main reason for the accidents originating from human error is as follows: for collision accidents, Convention on the International Regulations for Preventing Collisions at Sea (COLREG) violation and the lack of communication between vessels; and for grounding accidents, the interpretation failure of the officer on watch and lack of communication in the bridge resource management.     

波浪作用下30万吨级油轮撞击能量研究

通过物理模型试验,研究不规则波作用下30万吨级油轮撞击能量,分析了主要影响因素HT、LB、TT0、D对撞击速度的影响规律。结果表明:撞击速度与HT成正比;与LB成幂次关系;与TT0也成正比,但TT0=1时船舶撞击码头与波浪产生共振,撞击速度出现极大值;压载时的撞击速度大于满载时的撞击速度,撞击速度与吃水成负相关。提出了30万吨级油轮撞击能量的计算公式,与青岛港原油码头三期工程和青岛益佳集团燃油码头工程的物理模型试验结果对比,具有较好的计算精度,可供工程设计参考。     

徐圩防波堤工程桶式基础结构设计

桶式基础结构是一种新型防波堤结构,目前尚没有成熟的设计标准和施工工艺。结合连云港徐圩防波堤工程,介绍此结构的设计荷载工况、结构模型试验、有限元分析方法、配筋方法。通过对比土体-结构相互作用模型和简化独立桶体模型,说明两种分析方法的优劣。以实例对比说明中国规范和美国混凝土学会ACI 318规范关于双向板裂缝宽度的计算方法。     

低阻通风船体的远程控制测试平台开发（英文）

This paper addresses the development and testing of a remotely controlled boat platform with an innovative air-ventilated hull. The application of air cavities on the underside of ship hulls is a promising means for reducing hydrodynamic drag and pollutant emissions and increasing marine transportation efficiency. Despite this concept’s potential, design optimization and high-performance operation of novel air-cavity ships remain a challenging problem. Hull construction and sensor instrumentation of the model-scale air-cavity boat is described in the paper. The modular structure of the hull allows for easy modifications, and an electric propulsion unit enables self-propelled operation. The boat is controlled remotely via a radio transmission system. Results of initial tests are reported, including thrust, speed, and airflow rate in several loading conditions. The constructed platform can be used for optimizing air-cavity systems and testing other innovative hull designs. This system can be also developed into a high-performance unmanned boat.     

A havelock source panel method for near-surface submarines

A panel method is described for calculating potential flow around near-surface submarines. The method uses Havelock sources which automatically satisfy the linearized free-surface boundary condition. Outputs from the method include pressure field, pressure drag, wave resistance, vertical force, trim moment and wave pattern. Comparisons are made with model tests for wave resistance of Series 58 and DARPA SUBOFF hulls, as well as with wave resistance, lift force and trim moment of three length-to-diameter variants of the DSTO Joubert submarine hull. It is found that the Havelock source panel method is capable of determining with reasonable accuracy wave resistance, vertical force and trim moment for submarine hulls. Further experimental data are required in order to assess the accuracy of the method for pressure field and wave pattern prediction. The method is implemented in the computer code “HullWave” and offers potential advantages over RANS-CFD codes in terms of speed, simplicity and robustness.