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941.
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944.
Protective effect of glutamine pretreatment on ischemia-reperfusion injury of spinal cord in rabbits
Jian Lü 《西安交通大学学报(英文版)》2009,21(4):242-245
Objective To investigate the effect of glutamine (Gln) on the content of reduced glutathione hormone (GSH) and aminoglutaminic acid (Glu) of spinal cord following ischemia-reperfusion injury. Methods Totally 40 healthy adult male rabbits were randomly divided into five groups: sham-operation group (S group), ischemia-reperfusion injury group (I/R group), low-dose glutamine group (L Gln group), median-dose glutamine group (M Gln group) and high-dose glutamine group (H Gln group). After glutamine preconditioning, the model of spinal cord ischemia-reporfasion injury was established according to Zivin's method. The general status of animals was observed and the changes of Jacobs scoring were recorded in each group. Malondialdehydes (MDA), GSH, Glu and superoxide dismutase (SOD) activity in lumbar spinal cord tissues were determined using chemical colorimetry. The neuron number and deviation rate in spinal cord anterior horn were observed histopathologically. Results There was no significant difference between L Gin group and I/R group in behavior scoring, SOD activity, content of MDA and Glu, neuron number and deviation rate of spinal cord (P>0.05); however, there was a significant difference in GSH content of spinal cord (P<0.05). M Gln group and I/R group differed significantly (P<0.05) in behavior scoring, SOD activity, content of MDA, Glu, GSH, neuron number and deviation rate of spinal cord. Between H Gln group and M Gln group, there was no significant difference in behavior scoring, content of MDA and Glu, SOD activity, neuron number and aberration rate in spinal cord (P>0.05), whereas there was a significant difference in SOD activity and Giu content (P<0.05). Conclusion Pretreatment with medium-dose glutamine has a protective effect on spinal cord ischemia-reporfasion injury in rabbits, which may be related to the maintenance of GSH content, increase of SOD activity and reduction of MDA. 相似文献
945.
To solve the resource-constrained multiple project scheduling problem (RCMPSP) more effectively, a method based on timed colored
Petri net (TCPN) was proposed. In this methodology, firstly a novel mapping mechanism between traditional network diagram
such as CPM (critical path method)/PERT (program evaluation and review technique) and TCPN was presented. Then a primary TCPN
(PTCPN) for solving RCMPSP was modeled based on the proposed mapping mechanism. Meanwhile, the object PTCPN was used to simulate
the multiple projects scheduling and to find the approximately optimal value of RCMPSP. Finally, the performance of the proposed
approach for solving RCMPSP was validated by executing a mould manufacturing example. 相似文献
946.
Mobile ad hoc networks are often deployed in environments where the nodes of the networks are unattended and have little or
no physical protection against tampering. The nodes of mobile ad hoc networks are thus susceptible to compromise. The networks
are particularly vulnerable to denial of service (DoS) attacks launched through compromised nodes or intruders. In this paper,
we investigated the effects of flooding attacks in network simulation 2 (NS-2) and measured the packet delivery ratio and
packet delay under different flooding frequencies and different numbers of attack nodes. Simulation results show that with
the increase the flooding frequencies and the numbers of attack nodes, network performance drops. But when the frequency of
flooding attacks is greater than a value, the performance decrease gets smooth. Meanwhile the packet delay firstly increases
and then declines to a value of stability at the end. 相似文献
947.
948.
旧桥拓宽中拼接形式对旧桥受力的影响分析 总被引:1,自引:0,他引:1
结合合宁高速公路上一座连续刚构梁桥,应用空间有限元方法,分析了横向采用不连接、铰接、刚接等拼接方式时,汽车荷载作用下旧桥挠度、应力的变化及翼缘板根部应力状态。通过分析认为横向拼接有利于增大桥梁结构的整体刚度,减小旧桥挠度与梁体应力。随着拼接刚度增大,翼缘板悬臂根部应力变化较为复杂。 相似文献
949.
950.
The purpose of this study is to realize the intelligent deliberative obstacle avoidance for unmanned surface vehicle (USV), based on the International Regulations for Preventing Collisions at Sea called COLREGS. Firstly, a three-level system architecture is designed for the ship intelligent collision avoidance system. Secondly, an intelligent collision avoidance algorithm is presented based on the calculation of motion parameters and the rules of COLREGS. Thirdly, according to COLREGS, the marine environment is modeled from the electronic chart data and radar information, and a deliberative collision avoidance algorithm is written. Finally, the deliberative collision avoidance simulation is carried out for the USV. The feasibility and reliability of intelligent collision avoidance algorithm are verified by the vivid simulation results. 相似文献