沙棘果油及沙棘籽油对大鼠放射性皮肤损伤的影响

目的观察沙棘果油及沙棘籽油对大鼠放射性皮肤损伤的影响。方法实验用深部X线治疗机,每次以3000 cGy的剂量,照射两次,造成大白鼠臀部放射性皮肤损伤。待动物症状明显后,将Ⅱ度皮肤损伤的动物随机分为6组,即阴性对照组、沙棘果油高剂量组、沙棘果油低剂量组、沙棘籽油高剂量组、沙棘籽油低剂量组以及阳性对照组。沙棘果油及籽油高剂量组,每天在损伤部位涂药两次,而其低剂量组每天涂药一次,阴性对照组每天涂灭菌的注射用水一次,阳性对照组每天涂Solcoseryl-Jelly软膏一次。结果肉眼观察结果显示,连续用药10d后,沙棘果油、籽油及Sol-coseryl-Jelly组动物的局部红斑、水肿明显减轻,创面分泌物明显减少,用药2周后,上述症状明显消退,与阴性对照组比较,明显好转;另外,沙棘果油、籽油及Solcoseryl-Jelly组的创面愈合时间明显缩短。光学显微镜观察结果显示,沙棘果油、籽油及Solcoseryl-Jelly组的皮肤损伤明显减轻,炎症反应亦明显减轻,创面修复明显。电子显微镜观察结果显示,阴性对照组的超微结构明显受损,而沙棘果油、籽油及Solcoseryl-Jelly组的损伤明显减轻。结论沙棘果油及沙棘籽油对大鼠放射性皮肤损伤有明显的治疗作用。     

Modeling research on manufacturing execution system based on large-scale system cybernetics

A cybernetics model of manufacturing execution system(MES CM) was proposed and studied from the viewpoint of cybernetics.Combining with the features of manufacturing system, the MES CM was modeled by"generalized modeling"method that is discussed in large-scale system theory.The mathematical model of MES CM was constructed by the generalized operator model, and the main characteristics of MES CM were analyzed.     

爆破碎石填筑路堤压实控制的试验研究

形成优良的爆破碎石路基结构的关键在于有效的压实.结合锦州市黑山地区村通油路修建的工程实例,总结了爆破碎石路基压实质量控制的经验.     

综合重症监护病房患者呼吸机相关性肺炎的病原学和耐药性分析

目的探讨病原菌在综合重症监护病房(ICU)患者呼吸机相关性肺炎(VAP)中的分布及对常用抗生素的耐药情况。方法对我院2004-2006年综合ICU患者VAP病原菌的分布及耐药性进行回顾性统计分析。结果从302例综合ICU VAP患者下呼吸道深部分泌物标本中分离出347株病原菌,主要病原菌是铜绿假单胞菌(32.3%)、鲍曼不动杆菌(31.1%)、金黄色葡萄球菌(16.7%)、克雷伯菌(7.5%)与凝固酶阴性葡萄球菌(6.1%)。革兰阴性杆菌(G-杆菌)对哌拉西林、头孢噻肟耐药率最高,对碳青霉烯类及加酶抑制剂抗生素耐药率最低;革兰阳性球菌(G 球菌)对青霉素类、克林霉素及红霉素耐药率高,对万古霉素、喹诺酮类抗生素耐药率低。结论G-杆菌是综合ICU患者VAP最主要的病原菌,多重耐药性高;耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林凝固酶阴性葡萄球菌(MR-SCNS)的分离率高且耐药严重。临床医师应根据病原菌学及抗菌药物敏感性资料,及时选择合理的抗生素控制感染,延缓耐药菌株的产生。     

Study on T lymphocyte subsets and NK cells in patients with Graves＇ disease combined with type 2 diabetes

Objective To investigate changes in T lymphocyte subsets and NK cells in patients with simple Graves' disease (GD)and Graves' disease combined with type 2 diabetes mellitus (GD/T2DM). Methods Fifteen cases of GD/ T2DM were selected from our hospital from November 2001 to November 2004. Before and after therapy thyroid function, thyroglobulin antibody (TGA), thyroid microsomal antibody (TMA) and blood glucose level were measured, and T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and NK cells (CD56) were measured by immunofluorescence double labeling monoclonal antibody and flow cytometry, respectively. At the same time, comparison was made with simple GD (15 cases), T2DM (15 cases) and healthy control (20 cases). Results Before therapy, CD4/CD8, CD4 and NK cells in GD/T2DM were less than normal, and there was no significant difference in comparison with simple GD (P<0.05). In T2DM group, only CD4/CD8 and CD4 were less than those of healthy controls (P<0.05). When thyroid function recovered after 1 to 3 months of methimazole treatment in both GD/T2DM and simple GD groups, various indexes recovered, which were more obvious in simple GD. Conclusion Immune hypofunction of GD may be the key to the immune abnormality of GD/T2DM, which is more significant than that of simple GD or T2DM. The recovery of thyroid function and immune abnormality is not consistent, and the recovery of GD is more significant than that of GD/T2DM.     

某高速公路桥梁拓宽后伸缩缝锚固区混凝土破坏原因分析

结合九乡河大桥扩建工程,探讨了桥台处伸缩缝锚固区混凝土的有限元建模方法,着重研究了桥台处伸缩缝锚固区混凝土的破坏成因。分析表明,伸缩缝锚固区开裂的主要原因是新旧桥台的不均匀沉降,采用文中提供的建模方法,可以正确地模拟伸缩缝处混凝土的破坏,从而明确破坏机理,并为此类旧桥加宽工程的设计和施工提供借鉴。     

论稀浆封层、改性稀浆封层、微表处之异同

随着我国大量高速公路进入维修养护期,稀浆封层、改性稀浆封层、微表处等路面预防性养护技术受到了前所未有的关注。从定义、技术要求、应用范围等多方面出发,分析这三项预防性养护技术的异同,有助于公路工程者以科学的态、度,从实际情况出发,因地制宜,进行严格的甄选。     

Simulation and analysis of vehicle stability based on ADAMS/CAR differential brake

To improve the braking safety of automobiles, the author studied the effect of differential brake on the stabilities. To analyze the mechanical characteristics of differential brake, automotive subsystem models were built by applying ADAMS/CAR, and automotive mechanics simulation model was built by setting the main subsystems such as body, engine and brake. The simulation model studied the distribution mode of three kinds of differential brake, and beeline braking stability and turning braking stability were simulated. It shows that differential brake can amend turning shortage of automobile brake and improve its braking stability, but the effect of automobile mass on its braking stability is great. So the distribution mode of braking force and the effect of mass change should be considered while differential brake is applied.     

智能交通系统中信息情报板优化设计

信息情报板是智能交通系统中信息发布的主要手段之一,对其进行合理的结构设计,是保证信息发布效果的重要技术措施。在分析驾驶员从发现信息板到采取行动的全过程的基础上,提出的一种信息情报板结构优化模型．可用于信息情报板结构优化的实践当中。     

船舶在港时间及其管理与控制

船舶在港时间有较强的可压缩性,协调好船方、货主、码头作业和相关部门及单位的工作,是提高船舶在港作业效率,节省船舶在港时间的重要途径．