济南铁路局“新一轮质量管理知识普及教育”工作点滴

在简要论述全面质量管理工作重要性的基础上,叙述根据济南铁路局的具体实际情况,开展新一轮质量管理知识普及教育的培训计划、培训思路、具体培训工作过程和培训取得的效果。     

Establishment of a uremic apolipoprotein E knockout mouse model to explore the mechanism of uremic atherosclerosis

Objective To establish a uremic apoE-/- mouse model to observe serum biochemical parameters and features of aortic root atherosclerosis (AS) in the model. Methods A uremic model was induced surgically in apoE-/- mice: electrocautery of the right kidney at 8 weeks of age and nephrectomy (NX) of the left one 2 weeks later. Control mice were sham-operated. Two weeks after NX, renal functions were detected in the uremic and control mice to evaluate the efficiency of the model. After 10 weeks of NX, blood samples were taken to determine serum biochemical parameters, and aortic root was collected for frozen sections to investigate the lesion features of AS. Results Two weeks after NX, renal functions declined significantly in the uremic mice compared with the control ones, and remained stable 8 weeks later either in males or in females. Ten weeks after NX, serum levels of TCH, TG and LDL-C were dramatically higher in the uremic mice than in the controls, whereas no differences in serum HDL-C or glucose concentration were found between the two groups. Aortic root plaque relative area increased significantly in the uremic mice compared with the controls either in males or in females; more-over, the lesion area was larger in female mice than in male ones. Conclusion We established a uremic apoE-/- mouse model successfully, and this model is characterized by accelerated atherogenesis which is associated with an increase in serum lipid profile. This experimental model can be a useful tool to study the pathogenesis and therapeutic strategies of uremic AS.     

建立船舶设计技术参数参照体系研究

节能减排的要求对船舶设计产生了重大影响,船舶设计理念发生了变化。通过建立船舶资料库,分析船舶设计关键技术参数影响因素,充分发挥业界专家技术把关作用建立船舶设计技术参数参照体系,目的在于对业界进行顶层技术引导,把握船舶设计发展趋势,为船型升级换代及船型开发提供参考。     

工科大学生工程素质养成训练及评价方法研究

探讨了工科大学生工程素质的内涵,分析了工程素质养成训练的规律及子过程间相互关系。通过Fuzzy数学综合评判模型建立了工科大学生的工程素质养成训练过程评价体系,并对其进行了验证。帮助工科大学生了解应具备的基本工程素质和培养工程素质的路径和方法。     

利用数字式求积仪测量汽车迎风面积的探讨

汽车迎风面积是指汽车在行驶方向的投影面积,是求解汽车空气阻力系数的必要参数。作者发现目前使用的迎风面积测量方法存在精度不高或者测量方法繁琐等缺点,文中借鉴数码照相法,结合数字式求积仪,为汽车迎风面积的测量提供一种新的思路与方法。     

随机码调相脉冲多普勒引信抗干扰分析

针对新型随机码调相脉冲多普勒引信的原理进行了分析,对随机码引信中的随机二相码的模糊函数进行了仿真分析,通过对该引信的抗干扰仿真,验证了该引信的具有强抗干扰能力。     

VMT自动导向系统在盾构法施工中的应用和研究

利用自动仿真技术,结合应用广泛的测量仪器,针对盾构法地铁施工,采用无线数据传输功能,方便、快捷地将盾构机掘进姿态以图形和文字的双重效果实时显示在计算机屏幕上,指导盾构机操作手调整盾构掘进参数,可真正实现操作可视化、同步化。     

Mechanical Performance Analysis and Optimization of the Torsion Bar Suspension System in an Articulated Tracked Carrier

采用有限元法对某铰接履带式运输车扭杆悬挂装置的力学性能进行了分析,计算该悬挂装置的强度和刚度.最后对平衡肘进行了拓扑优化,根据优化结果和设计经验提出了结构改进措施,重新分析的结果表明,缩减平衡肘35％材料是可行的.     

肺癌患者血浆中血小板GMP－140的测定

采用ＧＭＰ－１４０单抗ＳＺ－５１采用酶联免疫吸附试验检测了７４例肺癌患者ＧＭＰ－１４０含量并与４０例健康人作了对照，结果发现肺癌患者血浆ＧＭＰ－１４０均值高于正常人（Ｐ＜０．０１），尤其在肺癌伴转移患者更为明显，且亦高于肺癌未转移患者（Ｐ＜０．０５），为进一步探讨血小板在肿瘤增殖与转移中的作用及临床治疗提供了参考依据。     

一类矩阵方程的可解性及通解表示

给出了矩阵方程()有解的一个充分必要条件,在可解的条件下,给出了通解的显式表示,作为应用,还讨论了矩阵方程AX+YB=D,()的可解性问题.