野三河大桥主墩底座高强大体积混凝土防裂施工技术

野三河大桥主墩底座为高强大体积混凝土结构,为防止出现裂缝,施工中采取了双掺技术优化混凝土配合比、合理设置后浇段以及采用冷却水管内散外蓄和选择有利浇筑时间降低混凝土最高温度等裂缝控制措施,以有效地控制混凝土的最高温度和内表温差.施工后的主墩底座混凝土内实外美,未产生任何裂缝,这表明上述技术对于防裂行之有效.     

缺锌儿童血清维生素A含量和5＇核苷酸酶活性观察

观察缺锌儿童血清维生素Ａ（ＶｉｔＡ）含量和５＇核苷酸酶（５＇－ＮＴ）活性的变化。结果表明，缺锌儿童血清ＶｉｔＡ含量和５＇－ＮＴ活性显著低于健康对照者（Ｐ＜０．００１）。锌剂治疗两月后，随着血清锌水平的提高，ＶｉｔＡ含量和５＇－ＮＴ活性明显升高。提示缺锌可影响小儿体内ＶｉｔＡ和核酸代谢。     

小儿铁缺乏症血清促甲状腺素含量及尿17—酮类固醇排量的研究

作者观察了47名铁缺乏症儿童血清促甲状腺素含量及64名尿17—酮类固醇排量在肌注右旋糖酐铁治疗前后的动态变化,并分别与32名及28名正常对照组者作了比较。结果显示:铁缺乏症各期儿童上述两项指标均值均高于对照组者,治疗后恢复正常,治疗前后数值统计学上有显著差异;各期间改变程度无差异。结果说明,铁缺乏时出现促甲状腺素及肾上腺皮质激素的代谢紊乱,这种紊乱与缺铁本身有关,与因缺铁而引起的贫血无关。     

大体积混凝土施工水化热温控措施及结果分析

结合实际工程承台混凝土浇筑实例,提出相应的水化热控制措施,通过MIDAS有限元仿真模拟,对施工阶段承台大体积混凝土浇筑进行试算研究。     

5000t级重载列车制动试验研究

本文通过制动定试验台试验及研究。分析了ＧＫ阀占绝大多数的情况下，普遍开行５０００ｔ级重载列车制动方面的问题，讨论了长大列车初充气、再充气性能与机车供风量的关系，提出了在列车纵向动力学计算中制动缸缓解特性的公式；针对ＧＫ型三通阀在长大编组中缓解次序紊乱，首先提出用阶图分析列车缓解时间特性的方法，对缓解波速解释提出了一些新的概念。     

Wave Number Method for Three-Dimensional Steady-State Acoustic Problems

Based on the indirect Trefftz approach, a wave number method (WNM) is proposed to deal with three-dimensional steady-state acoustic problems. In the WNM, the dynamic pressure response variable is approximated by a set of wave functions, which exactly satisfy the Helmholtz equation. The set of wave functions comprise the exact solutions of the homogeneous part of the governing equations and some particular solution functions. The unknown coefficients of the wave functions can be obtained by enforcing the pressure approximation to satisfy the boundary conditions. Compared with the boundary element method (BEM), the WNM have a smaller system matrix, and is applicable to the radiation problems since the wave functions are independent of the domain size. A 3D acoustic cavity is exemplified to show the properties of the method. The results show that the wave number method is more efficient than the BEM, and it is fairly accurate.     

白细胞介素-2对小鼠神经病理性痛的镇痛作用

目的探讨白细胞介素-2(IL-2)对神经病理性痛的镇痛作用及其可能的机制,为临床治疗神经病理性痛筛选新的镇痛药物奠定基础。方法通过结扎雄性C57BL/6小鼠单侧L5/L6脊神经建立神经病理性痛模型,然后利用机械刺激和冷刺激诱发的痛觉超敏实验分别观察腹腔注射不同剂量(1.0×106、2.5×106、5.0×106u/kg)IL-2对疼痛模型小鼠患侧脚掌痛阈的影响;同时,通过5.0×106u/kg IL-2注射前30 min腹腔注射纳洛酮(1 mg/kg)以观察阿片受体拮抗剂对IL-2镇痛作用的影响。结果腹腔注射IL-2可产生剂量依赖性镇痛作用,其中5.0×106u/kg和2.5×106u/kg IL-2均可显著提高模型小鼠患侧脚掌的50%缩足阈值(P<0.01)和降低5 min抬足次数(P<0.05),镇痛效应分别维持30 min和15 min,而1.0×106u/kg IL-2无明显的镇痛作用。IL-2产生的镇痛效应不能被纳洛酮阻断。结论IL-2对小鼠神经病理性痛具有镇痛作用,其镇痛效应除受阿片受体介导外还可能有其他分子参与。     

KCR—27型窗式空调器制冷系统模拟与优化

针对ＫＣＲ－２７型窗式空调器制冷系统，建立数学和物理模型，进行计算机模拟，并以能效比最大和空调器年总费用最低为目标，采用序贯有约束极小化方法中的混合罚函数法，运用计算机技术，地ＫＣＲ－２７型空调器进行优化并提出改进设计方案。     

碘对神经细胞生长分化蛋白NSE、NGF和IGFR表达的影响

目的　研究碘对体外神经细胞生长发育的直接影响及可能的作用机制。方法　采用体外新生大鼠皮层神经细胞培养法观察微量元素碘对神经细胞表达NSE、NGF和IGFR蛋白的影响。结果　①高浓度碘能增加体外培养的神经细胞表达NSE蛋白 ;②碘在培养的 5、6、7d时NGF蛋白的表达较对照组明显增强 ;③中、高浓度的碘能显著增强体外培养的大鼠皮层神经细胞IGFR蛋白的表达。结论　碘可能是通过促进、增强NSE、NGF和IGFR蛋白的表达 ,进而直接作用于体外培养的神经细胞 ,促进神经细胞的生长、发育与分化     

Calculation of 3D sensitivity matrix for electromagnetic tomography system using boundary elements and the perturbative approach

Electromagnetic tomography （EMT） is a non-invasive imaging technique capable of mapping the conductivity and permeability of an object. In EMT, eddy currents are induced in the object by the activation coils, and the receiving coils can measure the EMT voltages. When the activation frequency is significantly large, we can treat the metallic targets as electrically perfect conductors （EPCs）. In this situation, a thin skin approximation is reasonable and this type of scattering problem can be effectively treated by the boundary element method （BEM） formulated through integration equations. In this study, we compute three-dimensional （3D） sensitivity matrix between the sensors due to an EPC perturbation. Efficiency improvement is achieved through the utility of scalar magnetic potential. Two EPC objects, one sphere and one cube shaped, are simulated. The results agree well with the H dot H formula. Overall, we conclude that BEM can be used to calculate the 3D sensitivity matrix of an EMT system efficiently. This method is a general one for any shaped objects while the H dot H solution is only capable of producing the response for a small ball.