均布荷载作用下双面组合梁的滑移效应分析

利用基本力学方法对钢．混凝土双面组合梁在均布荷载作用下的滑移效应进行分析，推导得到了负弯矩区上、下交界面滑移沿梁长方向的表达式，并通过算例比较了双面组合梁与传统单面连续组合梁的滑移特点。计算表明，与传统单面连续组合梁相比，钢-混凝土双面组合连续梁不仅在负弯矩区提高了截面承载力，也使截面刚度得到了提高。     

大跨径连续刚构桥施工监控技术

为了保障施工过程的安全,在文昌大桥的施工过程中,在主桥控制截面布设了应变计,对施工过程中结构的应力变化进行跟踪监测,为桥梁施工提供安全预警;为了保证成桥线形满足设计要求,对悬浇过程中的主梁挠度进行跟踪监测与控制,为施工提供立模标高,并通过合理设置预拱度来控制梁体线形。     

Correlation of expression of ER, PR and c-erbB-2 with ultrasonographic features in invasive ductal cancer of breast

Objective To analyze the relationship of the expression level of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2, c-erbB-2) of breast invasive ductal carcinoma (IDC) with ultrasonographic characteristics. Methods Totally 104 patients with IDCs confirmed pathologically were involved in this study. ER, PR and c-erbB-2 expression in the IDC specimens was determined by immunohistochemical staining technique. The correlation between the ultrasonographic features and the positive expression of ER, PR or c-erbB-2 was analyzed. Results The positive expression rate of ER and PR in the group with tumor spiculation sign and posterior acoustic attenuation was higher than that in the group without. The positive expression rate of ER differed significantly (P<0.05) while that of PR did not (P>0.05). The over-expression rate of c-erbB-2 in the group of microcalcification, sufficient blood flow and axillary lymph node metastasis was higher than that in the group of non-microcalcification, deficient blood flow or without axillary lymph node metastasis (P<0.05). The expression of ER, PR and c-erbB-2 was not related to the size of tumor (P>0.05). Conclusion The expression of ER and c-erbB-2 is closely related to the ultrasonographic characteristics of IDC, which may, to some extent, reflect the expression level of ER and c-erbB-2.     

编码表皮生长因子受体Ⅲ型突变体PEP-3表位的cDNA的克隆

目的克隆出针对表皮生长因子受体Ⅲ型突变体(EGFRvⅢ)PEP-3表位的cDNA片段,为高表达EGFRvⅢ肿瘤的免疫治疗奠定基础。方法根据PEP-3的碱基序列设计出有12对互补碱基的正负引物,正负引物互为模板进行PCR扩增,制备出两端含酶切位点的PEP-3 cDNA片段,再将扩增的PCR产物亚克隆于载体pGEM-T Easy构建重组质粒pGEM-T Easy/PEP-3。结果经限制性内切酶酶切鉴定和DNA测序证实,编码PEP-3的cDNA片段被成功扩增并亚克隆于载体pGEM-T Easy中。结论成功克隆了编码表皮生长因子受体Ⅲ型突变体PEP-3表位的cDNA片段。     

政府工程采购的发展情况及存在问题

政府采购机制是规范化我国政府投资建设项目管理的一个重要工作领域。文章针对我国政府采购和政府工程采购的基本发展情况进行了说明,并对政府工程采购发展过程中存在的主要问题进行了分析。     

柴油机不同工况的活塞应力场有限元计算分析

利用SUPER SAP对Sulzer 6RND68柴油机在不同工况下的活塞应力场进行有限元计算分析，发现柴油机燃烧状况对活塞的应力场有着较大影响，尤其在燃烧质量不佳及柴油机超负荷运转时，其表现为活塞顶部的温度星指数上升；活塞当量应力最大值是在第1点，其当量应力值为1404MPa，此项研究为柴油机活塞顶部裂纹和烧蚀以及第一道活塞环断裂的原因提供了理论依据，为轮机管理人员提供了借鉴与参考．     

高速公路沥青路面裂缝病害原因及处治

本文介绍了高速公路沥青路面裂缝这一早期病害现象,分析了其产生的原因及危害性,结合目前我省高速公路路面裂缝的实际情况和近几年的灌缝实地经验,简要介绍了我省沥青路面裂缝的处治措施。     

Stability Analysis of Uncertain Discrete Time-Delay Control Systems

Based on Lyapunov stability theory, a less conservative sufficient condilions for the stabih＇lies of uncertain discrete delayindependent and delay-dependent control systems are obtained by using the linear matrix inequality （LMI） approach. Judgement of the stability of time-delay systems is transformed to judgement of the feasible solution of an LMI, and hence is solved by use of MATLAB. Numerical simulations verify the validity of the proposed method.     

Target priority determination methods by interval-valued intuitionistic fuzzy sets with unknown attribute weights

The paper aims at the problem of multi-targets threat degree being hard to be evaluated accurately in complex air defense battlefield environments. Combined with multi-sensors information fusion and interval-valued intuitionistic fuzzy sets (IVIFS) theories, the target priority determination is studied. The score and accuracy functions of IVIFS are improved with thinking about the hesitating information in order to increase the rationality. Then, the influence factors of target priority and the nonlinear relationship between the influence factors and target priority are analyzed. Next, the algorithms for calculating the factor weights and sensor weights are given. Based on the theory of IVIFS and technique for order preference by similarity to an ideal solution (TOPSIS), two methods of target priority determination based on the IVIFS and TOPSIS are proposed. At last, an application example verifies the effectiveness and flexibility of the proposed algorithms.     

基于物元分析法的公路桥梁损伤等级评定研究

在构建桥梁损伤等级评定指标体系的基础上,采用 AHP确定了各指标的权重,运用物元分析的方法建立了桥梁损伤等级评定的数学模型,并利用模型评定结果,得到了某桥梁的损伤等级。