CNG发动机工作过程的一维数值模拟

内燃机模拟计算是一种现代化的计算方法,可以减少试验次数及时间,从而节约内燃机开发和研究工作的人力、物力和财力.采用AVL BOO ST软件建立了某CNG发动机的整机模型,宏观上描述整个发动机的热力学过程,通过全负荷下的速度特性试验验证该模型的可靠性.并在此基础上,对影响CNG发动机性能指标的主要参数进行对比分析,提出改进措施.     

Dynamic Obstacle Avoidance for Application of Human-Robot Cooperative Dispensing Medicines

For safety reasons,in the automated dispensing medicines process,robots and humans cooperate to accomplish the task of drug sorting and distribution.In this dynamic unstructured environment,such as a human-robot collaboration scenario,the safety of human,robot,and equipment in the environment is paramount.In this work,a practical and effective robot motion planning method is proposed for dynamic unstructured environments.To figure out the problems of blind zones of single depth sensor and dynamic obstacle avoidance,we first propose a method for establishing offline mapping and online fusion of multi-sensor depth images and 3D grids of the robot workspace,which is used to determine the occupation states of the 3D grids occluded by robots and obstacles and to conduct real-time estimation of the minimum distance between the robot and obstacles.Then,based on the reactive control method,the attractive and repulsive forces are calculated and transformed into robot joint velocities to avoid obstacles in real time.Finally,the robot's dynamic obstacle avoidance ability is evaluated on an experimental platform with a UR5 robot and two KinectV2 RGB-D sensors,and the effectiveness of the proposed method is verified.     

基于红外路径识别的智能车控制系统设计

介绍一种基于模拟式红外光电传感器路径识别的智能车控制系统,使用飞思卡尔公司16位单片机MC9S12DG128为核心控制单元,采集红外传感器信号智能分析导引线路径信息,自动控制舵机转向,并对智能车的直流驱动电机实现PID调速控制。     

EFFECTS OF OUABAIN AND DIGOXIN ON THE GENE EXPRESSION OFSODIUM PUMP α-SUBUNIT ISOFORM IN AORTIC SMOOTH MUSCLE OF RATS

Accumulating evidence indicates that endoge-nous ligands of the digitalis receptor may exist inthe mammalian body, which has recently been de-scribed to be indistinguishable from ouabainL1'2j.Endogenous ouabain (EO) might induce many cy-tobiological changes and play an important role inregulating water and sodium metabolism and vas-cular tone in the body["'J. Many studies haveshowed that EO content in both hypertensive pa-tients and hypertensive animals is much more thanthose of normal subje…     

Surface reconstruction of scanned human body using radial basis functions and adaptive partition of unity

It is important to reconstruct a continuous surface representation of the point cloud scanned from a human body. In this paper a new implicit surface method is proposed to reconstruct the human body surface from the points based on the combination of radial basis functions (RBFs) and adaptive partition of unity (PoU). The whole 3D domain of the scanned human body is firstly subdivided into a set of overlapping subdomains based on the improved octrees. The smooth local surfaces are then computed in the subdomains based on RBFs. And finally the global human body surface is reconstructed by blending the local surfaces with the adaptive PoU functions. This method is robust for the surface reconstruction of the scanned human body even with large or non-uniform point cloud which has a sharp density variation. Foundation item: the National Natural Science Foundation of China (No. 50575139) and the Shanghai Special Fund of Informatization (No. 088)     

Protective effect of glutamine pretreatment on ischemia-reperfusion injury of spinal cord in rabbits

Objective To investigate the effect of glutamine (Gln) on the content of reduced glutathione hormone (GSH) and aminoglutaminic acid (Glu) of spinal cord following ischemia-reperfusion injury. Methods Totally 40 healthy adult male rabbits were randomly divided into five groups: sham-operation group (S group), ischemia-reperfusion injury group (I/R group), low-dose glutamine group (L Gln group), median-dose glutamine group (M Gln group) and high-dose glutamine group (H Gln group). After glutamine preconditioning, the model of spinal cord ischemia-reporfasion injury was established according to Zivin's method. The general status of animals was observed and the changes of Jacobs scoring were recorded in each group. Malondialdehydes (MDA), GSH, Glu and superoxide dismutase (SOD) activity in lumbar spinal cord tissues were determined using chemical colorimetry. The neuron number and deviation rate in spinal cord anterior horn were observed histopathologically. Results There was no significant difference between L Gin group and I/R group in behavior scoring, SOD activity, content of MDA and Glu, neuron number and deviation rate of spinal cord (P>0.05); however, there was a significant difference in GSH content of spinal cord (P<0.05). M Gln group and I/R group differed significantly (P<0.05) in behavior scoring, SOD activity, content of MDA, Glu, GSH, neuron number and deviation rate of spinal cord. Between H Gln group and M Gln group, there was no significant difference in behavior scoring, content of MDA and Glu, SOD activity, neuron number and aberration rate in spinal cord (P>0.05), whereas there was a significant difference in SOD activity and Giu content (P<0.05). Conclusion Pretreatment with medium-dose glutamine has a protective effect on spinal cord ischemia-reporfasion injury in rabbits, which may be related to the maintenance of GSH content, increase of SOD activity and reduction of MDA.     

苦参碱对人卵巢癌细胞增殖的影响及其机制

目的 研究苦参碱(matrine)体外培养的人卵巢癌细胞OV2008增殖的影响及相关机制.方法 采用四甲基偶氮唑蓝(MTT)比色法检测不同浓度(0、0.125、0.25、0.5、1.0,2.0、4.0 mg/mL)的苦参碱在不同的时间点(24、48、72 h)对OV2008细胞增殖的影响;采用流式细胞术(FCM)检测不同浓度的苦参碱作用于OV2008细胞48 h后细胞周期分布、凋亡率及Fas、Bcl-2蛋白的表达水平.结果 苦参碱对OV2008细胞的增殖具有明显的抑制作用,与对照组相比具有显著性差异(P<0.05或P<0.01),并呈现时间和剂量依赖性;细胞周期分析显示,随着苦参碱浓度的增高,G0/G1期细胞比例逐渐增加,S期细胞比例减小,G2/M期细胞比例无明显变化;苦参碱能够诱导细胞凋亡,且凋亡率随着苦参碱浓度的增高而升高(P<0.01);苦参碱能够上调Fas蛋白的表达(P<0.05或P<0.01),下调Bcl-2蛋白的表达(P<0.01).结论 苦参碱可显著抑制OV2008细胞的增殖,且抑制作用晕剂量和时间依赖性.苦参碱对OV2008细胞的增殖抑制作用可能与其诱导细胞周期阻滞及凋亡有关,而苦参碱诱导凋亡可能与其上调Fas蛋白表达、下调Bcl-2蛋白表达有关.     

同相牵引供电系统平衡补偿的最优模型

为消除同相牵引供电系统中的三相不平衡、滤除谐波、补偿无功,讨论了平衡变换的两种最优补偿模型:以波形质量最优为目标的波形畸变最小模型和以获得最佳负载为目标的最佳负载模型.通过仿真分析了系统电压畸变时两种补偿模型的补偿效果.结果表明,波形畸变最小模型使系统只提供负载所需要的基波有功电流,最佳负载模型将不对称的单相负载变成三相(或两相或四相)对称纯阻性负载.在三相系统电压对称无谐波时,两者补偿特性一致;当三相系统电压不对称有谐波时,两者补偿特性有区别.     

CASE-CONTROL STUDY FOR HOSPITAL INFECTIONS CAUSED BY GRAM-NEGATIVE BACILLI IN EMERGENCY INTENSIVE CARE UNIT

Objective To evaluate the potential patient factors associated with hospital infections caused by gram-negative bacilli in Emergency Intensive Care Unit(EICU).Methods A total of 146 patients with hospital infections were investigated.The method of retrospective case-control study and multivariable logistic regression analysis were adopted.Results Univariate analysis revealed relationship among numerous patient factors,and multivariate analysis revealed four factors to be associated independently with hospital infections caused by gram-negative bacilli:mechanical ventilation,corticoid use, length of stay,and coma.Conclusion The comprehensive preventive measures should be taken to deal with the risk factor of hospital infections in EICU.     

瑞芬太尼复合丙泊酚靶控输注在门诊隆乳术中的应用

目的探讨胸部美容手术行非气管插管全身麻醉中,不同浓度瑞芬太尼复合丙泊酚靶控输注的量效关系。方法选择ASAI-Ⅱ级行乳晕切口假体植入隆乳术女性患者,根据诱导期瑞芬太尼效应室靶浓度(0、1.0、1.5ng/mL)分为3组(n=20):C组(单纯丙泊酚组);REF1组(丙泊酚复合1.0ng/mL瑞芬太尼组);REF2组(丙泊酚复合1.5ng/mL瑞芬太尼组)。观察并记录患者不同时间点的血压、心率、脉搏氧饱和度及丙泊酚、瑞芬太尼的效应室浓度以及诱导期和维持期丙泊酚、瑞芬太尼用量和麻醉过程呼吸抑制、体动等不良反应,术后随访患者对麻醉的满意度。结果各组患者在不同时间点的血压、心率、脉搏氧饱和度、麻醉期间不良反应发生率的差异均无统计学意义(P>0.05),患者对麻醉满意率为100%;达到口头反应消失时,C组丙泊酚效应室浓度和诱导时间明显高于其余两组(P<0.05),且REF1和REF2组间比较无统计学意义(P>0.05)。结论小剂量(1.0～1.5ng/mL)瑞芬太尼复合丙泊酚靶控输注可满足胸部美容手术非气管插管全身麻醉需求,并且没有剂量依赖性效应。