5-羟色胺转运体基因多态性和抑郁症的发病、性别、严重程度及自杀行为的相关性

目的探讨中国汉族人群5-羟色胺转运体启动区(5-HTTLPR)基因多态性和抑郁症的发病、性别、严重程度及自杀是否相关。方法应用聚合酶链式反应(PCR)扩增技术测定150例抑郁症患者和150例正常对照者的5-HT-TLPR基因型和等位基因,分别验证各种基因型与中、重度抑郁症发病、性别及自杀行为的相关性。结果病例组SS、LS基因型及S等位基因频率均高于对照组(26.0% vs.20.0%;52.7% vs.46.0%;52.3% vs.43.0%;P均<0.05);两组性别分层比较,女性S等位基因频率高于对照组(55.3% vs.43.6%,P<0.05);病例组严重程度分层比较差异无统计学意义(P>0.05);病例组有无自杀行为分层比较,有自杀行为患者SS基因型频率(37.3% vs.20.2%)及S等位基因频率(61.8% vs.47.5%)均高于无自杀行为患者(P<0.05);抑郁自杀组性别分层比较未显示显著性差异(P>0.05);抑郁自杀组病情程度分层比较,重度抑郁自杀者SS基因型频率(42.5% vs.18.2%)及S等位基因频率(68.7% vs.36.4%)均高于中度抑郁自杀者(P<0.05)。结论在中国汉族人群中,5-HTTLPR多态性和抑郁症相关。S等位基因可能是抑郁症的易感基因,特别是女性,SS型可能是抑郁症易感基因型;S等位基因可能是抑郁症患者自杀的危险基因,SS基因型人群可能是抑郁症患者自杀的危险人群,特别是携带S等位基因的重度抑郁症患者更易自杀。     

Singular perturbation composite control of a free-floating flexible dual-arm space robot

The Free-floating Flexible Dual-arm Space Robot is a highly nonlinear and coupled dynamics system. In this paper, the dynamic model is derived of a Free-floating Flexible Dual-arm Space Robot holding a rigid payload. Furthermore, according to the singular perturbation method, the system is separated into a slow subsystem representing rigid body motion of the robot and a fast subsystem representing the flexible link dynamics. For the slow subsystem, based on the second method of Lyapunov, using simple quantitative bounds on the model uncertainties, a robust tracking controller design is used during the trajectory tracking phase. The optimal control method is designed in the fast subsystem to guarantee the exponential stability. With the combination of the two above, the system can track the expected trajectory accurately, even though with uncertainty in model parameters, and its flexible vibration gets suppressed, too. Finally, some simulation tests have been conducted to verify the effectiveness of the proposed methods.     

科考船多波束导流罩线型CFD分析方法与试验验证

针对于科考船多波束导流罩设计和船体线型设计缺少关联分析的主要问题,介绍了一种科考船导流罩线型与船体线型一体化CFD分析方法,综合考虑实船航行过程中船体型线和导流罩型线之间的相互影响。根据这种分析方法,分别对导流罩和船体组合线型的阻力性能和防气泡性能进行了CFD预报,并进行了船模试验。两者吻合良好,验证了此种CFD分析方法的工程实用性。     

Marine accident analysis for collision and grounding in oil tanker using FTA method

In this study, collision and grounding data registered in GISIS (Global Integrated Shipping Information System) were investigated for oil tankers. The database includes the information of the collision and grounding accidents during the period between 1998 and 2010 in oil tankers. The risk assessments were carried out using fault tree analysis (FTA) programme for the incidents as collision and grounding occurred in oil tankers. In this study, we were able to investigate first the potential problems which cause the collision and grounding accidents have been determined, second, the occurrence of accidents has been shown with causal factors by the FTA method, and, finally, the significance degree of the initial events causing occurrence of accidents have been put forth. Collision in oil tanker resulted in economical loss (81%), pollution (6%) and death or injury (13%). Grounding in oil tanker resulted in economical loss (91%) and pollution (9%). According to the FTA results, the main reason for the accidents originating from human error is as follows: for collision accidents, Convention on the International Regulations for Preventing Collisions at Sea (COLREG) violation and the lack of communication between vessels; and for grounding accidents, the interpretation failure of the officer on watch and lack of communication in the bridge resource management.     

波浪作用下30万吨级油轮撞击能量研究

通过物理模型试验,研究不规则波作用下30万吨级油轮撞击能量,分析了主要影响因素HT、LB、TT0、D对撞击速度的影响规律。结果表明:撞击速度与HT成正比;与LB成幂次关系;与TT0也成正比,但TT0=1时船舶撞击码头与波浪产生共振,撞击速度出现极大值;压载时的撞击速度大于满载时的撞击速度,撞击速度与吃水成负相关。提出了30万吨级油轮撞击能量的计算公式,与青岛港原油码头三期工程和青岛益佳集团燃油码头工程的物理模型试验结果对比,具有较好的计算精度,可供工程设计参考。     

徐圩防波堤工程桶式基础结构设计

桶式基础结构是一种新型防波堤结构,目前尚没有成熟的设计标准和施工工艺。结合连云港徐圩防波堤工程,介绍此结构的设计荷载工况、结构模型试验、有限元分析方法、配筋方法。通过对比土体-结构相互作用模型和简化独立桶体模型,说明两种分析方法的优劣。以实例对比说明中国规范和美国混凝土学会ACI 318规范关于双向板裂缝宽度的计算方法。     

分布电容对舰船电力系统接地方式选择的影响

本文主要讨论分布电容对舰船电力系统接地方式选择的影响,分析了舰船电力系统在高电阻接地和谐振接地的方式下分布电容对系统的影响,发现在中压系统中大分布电容的情况下,采用高电阻接地会产生超过有关标准的故障电流。在谐振接地的情况下,需要合理的配置消弧线圈来产生感性电流来抵消系统对地电容产生的容性残流。同时依据具体数据,利用高斯定理对电缆电容进行了估算,与实际结果相吻合。     

低阻通风船体的远程控制测试平台开发（英文）

This paper addresses the development and testing of a remotely controlled boat platform with an innovative air-ventilated hull. The application of air cavities on the underside of ship hulls is a promising means for reducing hydrodynamic drag and pollutant emissions and increasing marine transportation efficiency. Despite this concept’s potential, design optimization and high-performance operation of novel air-cavity ships remain a challenging problem. Hull construction and sensor instrumentation of the model-scale air-cavity boat is described in the paper. The modular structure of the hull allows for easy modifications, and an electric propulsion unit enables self-propelled operation. The boat is controlled remotely via a radio transmission system. Results of initial tests are reported, including thrust, speed, and airflow rate in several loading conditions. The constructed platform can be used for optimizing air-cavity systems and testing other innovative hull designs. This system can be also developed into a high-performance unmanned boat.     

A havelock source panel method for near-surface submarines

A panel method is described for calculating potential flow around near-surface submarines. The method uses Havelock sources which automatically satisfy the linearized free-surface boundary condition. Outputs from the method include pressure field, pressure drag, wave resistance, vertical force, trim moment and wave pattern. Comparisons are made with model tests for wave resistance of Series 58 and DARPA SUBOFF hulls, as well as with wave resistance, lift force and trim moment of three length-to-diameter variants of the DSTO Joubert submarine hull. It is found that the Havelock source panel method is capable of determining with reasonable accuracy wave resistance, vertical force and trim moment for submarine hulls. Further experimental data are required in order to assess the accuracy of the method for pressure field and wave pattern prediction. The method is implemented in the computer code “HullWave” and offers potential advantages over RANS-CFD codes in terms of speed, simplicity and robustness.