鸡胚提取物的营养成分及其抗氧化作用

目的分析鸡胚提取物的营养价值,探讨其对小鼠的补硒抗氧化作用。方法营养成分按国标方法测定;抗氧化试验采用硒营养不良模型动物法。100只小鼠分为3个剂量组和2个对照组,前4周,各剂量组和低硒对照组均喂饲低硒饲料,基础对照喂饲基础饲料。第5周起至第8周末,3个剂量组饲料中分别加入高、中、低剂量的鸡胚提取物,并用鸡蛋白粉调整各组饲料的蛋白质水平。结果每100 g鸡胚提取物中含蛋白质56.4 g,含K、Fe、Se分别为819 mg1、8.4 mg、139.0μg,维生素A、D、B2分别为1 679μg、21.25μg、2.61 mg等。第8周末,各剂量组小鼠全血硒水平恢复至基础对照组水平(P<0.05);高剂量组脑硒水平基本恢复(P<0.05);全血、脑、肾、肝组织中谷胱甘肽过氧化物酶活性随着处理剂量的增加而增强(P<0.05),全血、肾、肝组织中丙二醛(MDA)降低(P<0.05)。结论鸡胚提取物是一种优质蛋白质,含有丰富的矿物元素和维生素;鸡胚提取物能改善小鼠的硒营养不良状态,具有抗氧化作用。     

铅对大鼠海马神经细胞凋亡及Bcl-2、Bax基因表达的影响

目的　观察铅对大鼠学习记忆行为、海马神经元细胞凋亡及Bcl 2、Bax基因表达的影响 ,探讨铅对大鼠学习记忆行为及神经毒性损伤的可能机制。方法　 32只SD大鼠随机分为对照组和低、中、高铅剂量组 ,采用自由饮水染毒90d后建立动物模型。用TUNEL法测定海马神经元细胞凋亡状况 ;SP免疫组织化学技术观察Bcl 2、Bax蛋白表达。结果　TUNEL染色结果显示 :海马CA1、CA3、DG区各染铅组与对照组间神经元细胞凋亡指数 (AI)有非常显著性差异 (P <0 .0 1)。免疫组化染色结果显示 ,在海马CA1、CA3、DG区 ,Bcl 2蛋白表达阳性神经细胞均随染铅剂量增大而减少 ,各染铅组与对照组间有非常显著性差异 (P <0 .0 1) ;Bax蛋白表达阳性神经元细胞随染铅剂量增大而逐渐增多 ,各染铅组与对照组间比较有非常显著性差异 (P <0 .0 1)。结论　铅引起海马神经元细胞凋亡可能是铅损害学习记忆的重要机制之一 ,而铅可能通过影响凋亡调控基因Bcl 2、Bax诱导海马神经元细胞凋亡。     

Fault Diagnosis and Reliability Analysis Using Fuzzy Logic Method

A new fuzzy logic fault diagnosis method is proposed. In this method, fuzzy equations are employed to estimate the component state of a system based on the measured system performance and the relationship between component state and system performance which is called as “performance-parameter” knowledge base and constructed by expert. Compared with the traditional fault diagnosis method, this fuzzy logic method can use human＇s intuitive knowledge and dose not need a precise mapping between system performance and component state. Simulation proves its effectiveness in fault diagnosis. Then, the reliability analysis is performed based on the fuzzy logic method.     

强横风环境下棚车侧壁外形气动性能

强横风引起的气动横向力和气动升力是造成列车被吹翻事故的主要原因。空棚车由于其侧壁迎风面积大且质量轻,很容易在强横风作用下发生倾覆事故。采用流场数值计算方法,对垂直侧壁、弧形侧壁和外折形侧壁3种棚车外形方案,研究了横风作用下的棚车空气动力特性:气动横向力、升力和气动倾覆力矩。研究结果表明:车体受到的气动倾覆力矩主要是由气动横向力产生的;弧形侧壁和折形侧壁可以有效地改善车辆横向气动性能,降低车辆的气动倾覆力矩,提高车辆的稳定性;与垂直侧壁棚车相比,当车体宽度为3.2 m时,弧形侧壁和外折形侧壁棚车的气动倾覆力矩均可以下降21%左右,空载棚车倾覆临界风速可以提高2.7 m2.s-1。     

苏通大桥主塔桩基工程进度计划控制

苏通大桥主塔桩基是一超大型深水钻孔灌注桩基础,是苏通大桥项目关键控制性工程,受工程规模、气候、环境等因素影响,其计划工期安排存在不确定因素较多,进度控制困难。本文从工期安排、资源配备、施工条件等方面详细介绍了苏通大桥主塔桩基计划安排、施工进度控制、工效分析等。     

基于路径的行程时间可靠度评价方法研究

平均行程时间是交通运行评价工作及信息发布中经常使用的参数,但计算过程中由于采用算术平均而往往丢失了很多有用信息,其中就包括可靠度情况.因为现实中对于同一路径不同日期的相同时刻行程时间也是不一样的,人们为了准时到达目的地,出行前往往需要根据过去若干天的经验预估可能的异常情况影响,而这恰好是当前平均速度等交通指标所不能表示的.文章针对能准确反映这种不确定性对出行者产生影响的行程时间可靠度指标,进行分析及实证研究.     

Symptom monitoring in treatment of cancer patients

Objective To examine self-reported symptoms by the patients receiving cancer therapy, and find out the symptoms that should be coped with and managed during the treatment. Methods A pilot study was conducted on self-reported symptoms on 185 patients receiving chemotherapy and/or radiotherapy for different cancers. The Therapy-Related Symptoms Checklist (TRSC) was used. Results Severe symptoms on the TRSC subscales: loss of appetite,feeling sluggish, weight loss, nausea and hair loss, were reported by the patients. The frequently reported symptoms by those on chemotherapy were nausea, feeling sluggish, weight loss, vomiting, and taste change. The frequently reported symptoms by those on radiotherapy were feeling sluggish, weight loss, loss of appetite, difficult sleeping, and changing taste. The symptoms of loss of appetite, feeling sluggish, weight loss, hair loss, and nausea were both frequently reported by those on radiotherapy and those on chemotherapy. Conclusion Symptom monitoring may be facilitated by TRSC, based on the severity and frequency of reported symptoms, more patients and caregivers could know which symptoms should be preferential interventions.     

石林至锁龙寺高速公路弥勒采空区方案设计

根据工程地质勘探资料,采用全充填压力注浆法及抗变形桩的综合治理方案对采空区进行治理,可为类似工程项目提供参考和借鉴。     

提高大型金属结构疲劳寿命的措施

为提高大型金属结构疲劳寿命,采用了应力幅值理论。介绍了焊接结构件的结构细节、结构形式、焊接形式和结构工艺,论证了焊接接头细部构造类型对焊接结构件疲劳强度的影响,提出若干改进措施。实施后在新造大型金属结构件中焊缝和整体构件呈现出良好抗疲劳性能,获得很好效果。     

温福线无线通信系统集成的问题思考

简要介绍温福线无线通信系统集成实施过程中遇到的问题,并提出解决方案。