兔心房室隔过渡细胞的传导性及其电生理基础

目的　探索过渡细胞电生理特性与形态特征间的内在联系。方法　选 10只家兔做房室隔水平面及矢状面连续切片 ,HE染色观察。另 2 0只家兔采用标准玻璃微电极技术测定房室隔区正向传导速度。结果　房室结后方有两束过渡纤维分别延续至冠状窦口及其下方 ,分别为右后房结束和右下房结束 ,传导速度分别为 (0 .0 5 9± 0 .0 18)m·s-1和(0 .0 5 8± 0 .0 15 )m·s-1(P >0 .0 5 )。界嵴下段普通房肌传导速度为 (0 .2 0 3± 0 .0 4 0 )m·s-1。与前两者间均有显著性差异 (P <0 .0 1)。另外 ,过渡细胞动作电位有 4期自动除极 ,最大舒张电位 (- 6 3± 6 )mV ,普通房肌细胞无 4期自动除极 ,静息电位 (- 72± 4 )mV ,两者有显著性差异 (P <0 .0 5 )。结论　过渡细胞属慢反应自律细胞 ,传导速度比普通房肌慢。     

妊娠大鼠对急性心肌缺血损伤的反应及其机制

目的探讨妊娠鼠是否比正常生理状态能更好地耐受心肌缺血损伤以及发生的可能机制。方法雌性SD大鼠20只,早孕SD大鼠10只,分为正常对照组、未孕心梗组及早孕心梗组,于造模后3周使用Image 1.31软件,测量心肌梗死范围。使用powerLAB 4.12系统进行血流动力学测量,并应用TUNEL法检测细胞凋亡,Massion染色观察心肌胶元。结果早孕心梗组梗死范围为28.86%,未孕心梗组为36.8%。早孕心梗组心肌梗死范围较未孕心梗组明显减小;心梗3周后早孕心梗组左室收缩末压下降及左室舒张末压升高均较未孕心梗组为轻。两组凋亡指数比较早孕心梗组凋亡指数明显高于未孕心梗组。Massion染色显示:早孕心梗组心肌胶元含量明显较未孕心梗组少。结论妊娠对大鼠急性心肌缺血损伤有保护作用。     

基于Smart Client的工程管理信息系统框架分析

随着中国基础建设高峰到来,工程项目管理信息系统(PM IS)必将是大型基建工程项目管理的重要手段。阐述了基于Smart C lient模式PM IS的优点,并着重分析系统基本框架,提出了一般性设计原则,为PM IS开辟一条全新的研发思路。     

犬心房室隔内细胞形态学特征

目的　通过观察犬心房室隔内细胞形态学特征 ,探讨其可能的功能意义。方法　利用光学显微镜 ,通过HE和Masson染色对犬心房室隔标本的细胞形态、排列方式、直径和染色深浅进行细致观察 ,通过透射电镜观察证实光镜所见细胞特征。结果　①心房扩展部可见到四条过渡细胞束与房室结相连 :Ⅰ径自冠状窦壁沿锥形间隙或室间隔肌与右房肌之间向前至房室结后端 ;Ⅱ径自冠状窦口周围沿右房心内膜下至房室结浅层 ;Ⅲ径经三尖瓣隔侧瓣与冠状窦口之间向前经心内膜下至房室结右后端并至房室结的浅层 ;Ⅳ径自左侧心房肌向右下沿室间隔肌上缘至房室结左后端。低倍镜下纤维排列较疏松 ,纤细 ,直径约 9.5 μm ,染色浅淡。高倍镜下细胞呈长形 ,核长圆形与细胞长轴方向一致 ,细胞质染色淡。电镜下细胞特征符合过渡细胞特点。②冠状窦周围见到大量T细胞和少量P细胞及浦肯野细胞。结论　犬心房室隔内有过渡细胞构成的新传导径路 ;冠状窦可能是一个重要的潜在起搏点     

多智能体理论在车辆底盘集成控制中的应用

针对目前车辆底盘各子系统协调控制的不足,提出了一种基于多智能体(Multi-Agent)理论的底盘集成控制技术.针对半主动悬架、电动助力转向、轮胎、故障诊断等智能体的属性和特点,利用分层递阶控制方法结合多智能体理论,建立了集成系统协调求解机制,解决了半主动悬架和电动助力转向的匹配和协调控制问题,为车辆底盘系统的集成控制提供了一种新的理论方法和途径.     

交通工程项目目标管理探讨

为了准确、准时地完成考核指标,进一步提高部门及工程项目的管理质量,需要研究交通工程项目目标管理并在实践中提升其水平.根据交通工程项目目标管理的特点,采用链接分解目标,观察目标完成进展情况,进行信息评估和反馈处理,确保各项考核指标顺利完成.实践表明,目标管理方法可行,实用性强,能有效降低管理成本.     

简析轨道交通车载CCTV技术

简要介绍轨道交通车载CCTV系统的基本原理和功能,并给出相关的设备配置和无线图像传输技术的基本应用,为车载安防系统的应用提供参考。     

基于模具设计与制造专业“双证书”课程的研究与实践

双证融通是职业教育的本质要求,本文通过模具设计与制造专业工作过程分析与职业资格证书标准分析,将职业标准融入课程标准之中,在此基础上,提出模具设计与制造专业双证融通专业培养方案的框架体系。     

High-frequency random vibration analysis of a high-speed vehicle–track system with the frequency-dependent dynamic properties of rail pads using a hybrid SEM–SM method

A hybrid Spectral Element Method (SEM)–Symplectic Method(SM) method for high-efficiency computation of the high-frequency random vibrations of a high-speed vehicle–track system with the frequency-dependent dynamic properties of rail pads is presented. First, the Williams-Landel-Ferry (WLF) formula and Fractional Derivative Zener (FDZ) model were, respectively, applied for prediction and representation of the frequency-dependent dynamic properties of Vossloh 300 rail pads frequently used in China's high-speed railway. Then, the proposed hybrid SEM–SM method was used to investigate the influence of the frequency-dependent dynamic performance of Vossloh 300 rail pads on the high-frequency random vibrations of high-speed vehicle–track systems at various train speeds or different levels of rail surface roughness. The experimental results indicate that the storage stiffness and loss factors of Vossloh 300 rail pad increase with the decrease in dynamic loads or the increase in preloads within 0.1–10,000?Hz at 20°C, and basically linearly increase with frequency in a logarithmic coordinate system. The results computed by the hybrid SEM–SM method demonstrate that the frequency-dependent viscous damping of Vossloh 300 rail pads, compared with its constant viscous damping and frequency-dependent stiffness, has a much more conspicuous influence on the medium-frequency (i.e. 20–63?Hz) random vibrations of car bodies and rail fasteners, and on the mid- (i.e. 20–63?Hz) and high-frequency (i.e. 630–1250?Hz) random vibrations of bogies, wheels and rails, especially with the increase in train speeds or the deterioration of rail surface roughness. The two sensitive frequency bands can also be validated by frequency response function (FRF) analysis of the proposed infinite rail–fastener model. The mid and high frequencies influenced by the frequency-dependent viscous damping of rail pads are exactly the dominant frequencies of ground vibration acceleration and wheel rolling noise caused by high-speed railways, respectively. Even though the existing time-domain (or frequency-domain) finite track models associated with the time-domain (or frequency-domain) fractional derivative viscoelastic (FDV) models of rail pads can also be used to reach the same conclusions, the hybrid SEM–SM method in which only one element is required to compute the high-order vibration modes of infinite rail is more appropriate for high-efficiency analysis of the high-frequency random vibrations of high-speed vehicle–track systems.     

国内外摩托车ABS制动系统测试方法介绍(1)

随着摩托车行业的发展,人们越来越注重摩托车的安全性能,摩托车制动系统作为衡量摩托车安全性能的关键指标,成为各大摩托车企业关注和科研投入的重点课题,ABS防抱制动系统作为高级制动系统,已经逐渐应用在了中高端摩托车上,随着新系统的应用,世界各国和地区的检测标准也在不断更新,本文重点介绍国内外摩托车ABS制动标准的主要内容和差异,以供大家参考.