克服试验误差

新型高选择性药品的出现推动更大更复杂试验的趋势。日益增长的治疗复杂性激发西欧和北美的研究者寻找方法来实现临床增长的要求。     

机构法结合遗传算法优化拱桥设计

对结构工程师来说,设计优化正变得日益重要。该文描述了一种结合机构法和遗传算法进行整体化设计优化的方法。前种方法是当前英国交通部采用的一种主要的计算拱的工具;后者是强有力的数值函数优化方法。文中显示了英国肯特Teston桥和一系列其它样本设计优化的试算结果及相关的算法有效性数据。建议本方法为涉及现存桥梁的评估、维护和修理及新拱桥设计的结构工程师的设计辅助工具。     

Effect of drowsiness on driving performance variables of commercial vehicle drivers

Driver drowsiness is a major safety concern, especially among commercial vehicle drivers, and is responsible for thousands of accidents and numerous fatalities every year. The design of a drowsiness detection system is based on identifying suitable driver-related and/or vehicle-related variables that are correlated to the driver’s level of drowsiness. Among different candidates, vehicle control variables seem to be more promising since they are unobtrusive, easy to implement, and cost effective. This paper focuses on in-depth analysis of different driver-vehicle control variables, e.g., steering angle, lane keeping, etc. that are correlated with the level of drowsiness. The goal is to find relationships and to characterize the effect of a driver’s drowsiness on measurable vehicle or driving variables and set up a framework for developing a drowsiness detection system. Several commercial drivers were tested in a simulated environment and different variables were recorded. This study shows that drowsiness has a major impact on lane keeping and steering control behavior. The correlation of the number and type of accidents with the level of drowsiness was also examined. Significant patterns in lateral position variations and steering corrections were observed, and two phases of drowsiness-related degradation in steering control were identified. The two steering degradation phases examined are suitable features for use in drowsiness detection systems.     

Constrained Optimal Control of Semi-Active Suspension Systems with Preview

Controllers for semi-active suspensions have to account for constraints on damper range, tire force and suspension travel. Two approaches to incorporate these constraints in the design of controllers to minimize peak values in the chassis acceleration are considered. It is assumed that information on the oncoming road elevations (preview) is available. In the soft constraint approach, the constraints on tire force and suspension travel are included in a quadratic performance index. Two clipped optimal control laws, which deal with preview in a different way, are presented. Simulation results with a 2-DOF vehicle model on some rounded pulses show that these laws do not work satisfactorily with respect to the constraints. Therefore, the control problem is reformulated as a constrained optimization problem with hard constraints on tire force and suspension travel. Simulations with the same model on the same rounded pulses show that the hard constraint approach handles the constraints more properly.     

Simulation and Visualisation of the Dynamic Behaviour of an Overhead Power System with Contact Breaking

For high speed rail traffic it is necessary to design overhead power systems which minimize the contact loss between pantograph head and contact wire. To predict how different design solutions will behave it is favourable to model and simulate the dynamic behaviour. In this paper a model of an overhead power system is specified and used in simulation. The model is suitable for simulation with contact loss since it includes specifications of impact conditions between pantograph head and contact wire. Two sets of equations of motion are specified, one for the contact case and one for the non-contact case. The model also includes lateral movement of the wire due to the zigzag span and friction between the pantograph head and the contact wire. It is shown how to make animations of the system behaviour using a MCAE-system. The animations are made using a geometrical model of the system together with results from numerical simulations.

Through the examples provided, use of the mathematical model and the geometrical model is presented. The response is visualised as time histories and phase plane diagrams of different coordinates and as animations of the total system response. The different types of visualisations make an excellent combination when studying the system behaviour of different design solutions.

In one example, simulation using the linearised set of equations gives the same results as simulation using the set of fully nonlinear equations, due to periodic response and the simple alternation of contact conditions. It is shown that the situation when any of the parameters vary suddenly is possible to simulate using the fully nonlinear equations of motion.     

Force Control in Electrohydraulic Active Suspensjons

For a simple vehicle active suspension system complete optimality and zero steady state body displacements may be achieved if the axle and body accelerations, and other easily measured quantities, are included in the performance index. Apart from not requiring an observer, this also allows the optimal feedback gains to be determined for an arbitrary body spring rate. In a theoretical example, model parameters matching those of an experimental test rig are employed. The results of computer simulations, with and without an electrohydraulic servovalve and actuator, are compared to demonstrate the effects of inner loop gain on force control. Aspects of the system behaviour including lockup are commented upon.     

Hydro-pneumatic Slow-active Suspension with Preview Control

In this work, the preview control problem is considered for fully active and hydro-pneumatic slow-active systems. Based on the quarter car model, linear optimal control theory is used to derive the control laws. The Pade approximation technique is used to represent the preview time resulting from a preview sensor mounted at the front bumper to measure the road irregularities ahead of the front wheels. The results for the slow-active system with preview showed that there is 15% improvement in ride comfort compared to slow-active without preview and 28.5% improvement over passive system at similar root mean square (r.m.s) dynamic tyre load and suspension working space. The performance gains are, however, lower by about 15% than those obtainable with the theoretically ideal, fully active system with preview. The power results for slow active with and without preview showed that a 2kW fixed displacement hydraulic pump is enough for full vehicle requirements.     

The Influence of In-Plane Tyre Dynamics on ABS Braking of a Quarter Vehicle Model

For efficient analysis it is important to choose the proper model that fits the problem that needs to be solved. This paper discusses three pragmatic simulation models for longitudinal behaviour of a passenger car tyre (Steady State, Transient and Rigid Ring) that may be used in e.g. an ABS simulation. The characteristics of the simulation models are evaluated using some simple simulations. Simulations with a quarter vehicle model that includes load transfer effects are carried out to determine the deviation in results between the mentioned tyre models for an ABS application. The results show that the Steady State model may only be used below 10 Hz and that the Transient model is valid up to about 30 Hz. The results from the ABS simulation with the Rigid Ring model are most reliable and are clearly different from the Steady State and Transient model, which indicates that ABS simulations should be carried out with the Rigid Ring model. Additionally it is demonstrated that for tyre behaviour on uneven roads the influence of the tyre belt cannot be neglected.     

The Propagation of Waves in a Semi-Infinite Chain of Material Points and Springs Representing a Long Train

The dynamical behaviour of the longitudinal motion of a long train on which tractive or braking forces apply, often is investigated by representing the train by a model consisting of a continuous bar in which longitudinal vibrations can occur. In the present publication a model consisting of a chain of material points and springs is proposed. It can be investigated by means of difference equation methods and of Laplace transformations. In certain respects the discrepancies of the results with those obtained for a continuous model, are considerable and it may be concluded that a more complete investigation of the discrete model is necessary.     

Dynasim 3: A Computer Program for Simulation Of Vehicle Riding Motions

The purpose of this paper is to present analytical techniques for evaluating the dynamic riding behaviour of a vehicle. These techniques have been applied to a fairly sophisticated model of a bus, where a three-dimensional structure, elastic frame and non-linear shock-absorbers have been considered.

A computer simulation program (DYNASIM 3) has been set up, which is actually used at FIAT corporation for evaluating vehicle riding qualities and improving the design process.