CT reconstruction with priori MRI images through multi-group datasets expansion

Computed tomography (CT) reconstruction with a well-registered priori magnetic resonance imaging (MRI) image can improve reconstruction results with low-dose CT, because well-registered CT and MRI images have similar structures. However, in clinical settings, the CT image of patients does not always match the priori MRI image because of breathing and movement of patients during CT scanning. To improve the image quality in this case, multi-group datasets expansion is proposed in this paper. In our method, multi-group CT-MRI datasets are formed by expanding CT-MRI datasets. These expanded datasets can also be used by most existing CT-MRI algorithms and improve the reconstructed image quality when the CT image of a patient is not registered with the priori MRI image. In the experiments, we evaluate the performance of the algorithm by using multi-group CT-MRI datasets in several unregistered situations. Experiments show that when the CT and priori MRI images are not registered, the reconstruction results of using multi-group dataset expansion are better than those obtained without using the expansion.     

高速路网不停车收费车道优化布设方法

合理设置高速公路收费站ETC (Electronic Toll Collection)车道数量，对高速公路通行效率至关重要。针对目前路网中ETC与MTC (Manual Toll Collection)车辆混行的情况，考虑ETC的普及率，结合多用户路网均衡模型和排队论方法，建立基于双层规划模型的高速路网ETC车道优化布设方法。上层模型以车辆总通行时间最小为目标，优化设置进出收费站的ETC车道数量；下层模型为多用户路网均衡模型，反映ETC和MTC车辆的路径和收费车道选择行为。下层模型通过设计收费站的等价拓扑结构，表征收费站的车道使用规则及车辆的收费车道选择行为，并采用排队论方法估计ETC和MTC车道的收费排队时间。根据模型的特点设计了基于主动集的启发式算法，利用参数二进制与拉格朗日函数法确定迭代下降方向，解决了下降方向与步长难以计算的问题；通过内嵌优化函数的方式，保证在主动集转化过程中上层约束均不会失效，且避免了迭代过程中的模型解退化问题。基于上海市绕城高速进行实证分析，结果表明：随着ETC普及率的提升，收费排队时长按照负指数趋势下降；与按比例布设ETC车道的方法相比，所提方法最高可降低57.4%的收费排队时间，且该方法可以避免ETC车道布设过多对于MTC车道通行能力挤压造成的负面效果。研究成果可以有效指导高速路网ETC车道的布设，提高路网通行效率。     

Reliability Modeling and Maintenance Policy Optimization for Deteriorating System Under Random Shock

Performance degradation and random shock are commonly regarded as two dependent competing risks for system failures. One method based on effective service age is proposed to jointly model the cumulative effect of random shock and system degradation, and the reliability model of degradation system under Nonhomogeneous Poisson processes (NHPP) shocks is derived. Under the assumption that preventive maintenance (PM) is imperfective and the corrective maintenance (CM) is minimal repair, one maintenance policy which combines PM and CM is presented. Moreover, the two decision variables, PM interval and the number of PMs before replacement, are determined by a multi-objective maintenance optimization method which simultaneously maximizes the system availability and minimizes the system long-run expect cost rate. Finally, the performance of the proposed maintenance optimization policy is demonstrated via a numerical example.     

关于构建海上医疗救助制度的探讨

文中通过分析海上医疗救助与海上人命救助的区别,指出建立海上医疗救助制度的意义,并对建立此制度的途径进行了有益的探讨。     

Novel experimental strategy for high resolution AFM imaging of membrane-associated bacterial toxins

Bacterial pore-forming toxins （PFTs） are essential virulence factors of many human pathogens. Knowl- edge of their structure within the membrane is critical for an understanding of their function in pathogenesis and for the development of useful therapy. Atomic force microscopy （AFM） has often been employed to structurally interrogate many membrane proteins, including PFTs, owing to its ability to produce sub-nanometer resolution images of samples under aqueous solution. However, an absolute prerequisite for AFM studies is that the samples are single-layered and closely-packed, which is frequently challenging with PFTs. Here, using the prototypical member of the cholesterol-dependent cytolysin family of PFTs, perfringolysin O （PFO）, as a test sample, we have developed a simple, highly robust method that routinely produces clean, closely-packed samples across the entire specimen surface. In this approach, we first use a small Teflon well to prepare the supported lipid bilayer, remove the sample from the well, and then directly apply the proteins to the bilayer. For reasons that are not clear, bilayer preparation in the Teflon well is essential. We anticipate that this simple method will prove widely useful for the preparation of similar samples, and thereby enable AFM imaging of the greatest range of bacterial PFTs to the highest possible resolution.     

小直径盾构施工中管片纵向应力监测研究

为了探索小直径盾构法隧道在施工过程中管片纵向应力的变化规律,对北京槐房再生水厂污水隧道管片纵向应力进行了现场监测:将第976环、第1 054环管片分别设为第1和第2监测断面,2监测断面各预埋5个纵向应力计,各监测断面从本监测断面管片安装后即开始监测,当盾构掘进至第1 129环时停止监测。研究表明:1)在管片离开盾尾50环后,其纵向应力波动值小于管片拼装期间应力值的5%。2)在盾构掘进期间,管片距离盾构越远,其纵向压应力值越小。3)在管片拼装期间,管片距离盾构越远,其纵向压应力经历了先增大后减小的过程。4)管片距离盾构108环后,该管片纵向压应力趋近于0.2~0.3 MPa。5)随着盾构推进,管片纵向应力经历了4个阶段的变化过程,即周期性剧烈波动阶段—动态稳定阶段—逐渐衰减阶段—趋于稳定阶段。     

乙醇汽油对车辆颗粒物排放的影响

在符合国Ⅰ、国Ⅲ、国Ⅴ标准的3辆试验车上,分别燃用国Ⅴ汽油、低芳烃E10、低烯烃E10 3种燃料,进行了NEDC和WLTC工况下的常温冷起动排放试验,重点对颗粒物(PM)排放量和粒子数量(PN)进行分析。结果表明:在两种工况下,燃用乙醇汽油相比普通汽油能大幅降低车辆的PM排放,低芳烃E10对国Ⅰ和国Ⅲ车辆PM降低效果最明显,分别下降19%和35%,低烯烃E10对国Ⅴ车辆PM降低效果最好,下降46%;在WLTC工况下燃用乙醇汽油能大幅降低车辆PN排放,其中低芳烃E10平均降低43%,低烯烃E10平均降低32%。     

混凝土箱梁温度作用的参数分析

根据非稳态导热偏微分方程,施加合适的边界条件,用有限元法进行了混凝土箱梁温度场的参数分析,并确定了影响混凝土箱梁温度场的主要因素。研究表明,混凝土箱梁的截面尺寸、所用混凝土的热物理性质以及气温对混凝土箱梁的竖向最大温度的影响均不大,对混凝土箱梁竖向温度梯度影响最大的是太阳辐射强度。     

关于公交停靠站影响区范围的研究

随着城市公共交通系统的发展,公交停靠站对道路交通流的影响已逐渐引起人们的注意。分析公交停靠站的影响首先应该对停靠站的影响区范围进行界定。在分析前人研究成果的基础上,基于交通波理论,按考虑超车与否,分析公交停靠站的影响区范围长度,得到不同交通流密度条件下公交停靠站影响区长度的计算公式。     

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国家体育场作为北京奥运会的主会场成功地承担了开闭幕式和田径赛事任务。本文研究了其停车场车辆的交通疏散问题,制定了疏散方案。首先,分析了国家体育场停车场和泊位布局及车辆疏散的具体条件。其次,通过给定环境的场景和参数设定,对具体的奥运场馆停车场车辆的疏散方案进行了仿真和评价。最后,利用奥运会开幕式的车辆疏散实测数据进行了对比分析,在仿真中要员和贵宾车辆的总疏散时间为26min,而奥运会开幕式车辆疏散实测结果表明,全部要员、贵宾疏散完毕,共用时27min,从而验证了车辆疏散方案的准确性和实用性。