Effect of ulinastatin on hepatic ischemia-reperfusion injury in rats

Objective To investigate the effect of ulinastatin (UTI) on hepatic ischemia-reperfusion injury in rats. Methods Totally 24 adult Sprague-Dawley rats were randomly divided into 3 groups: sham-operated control group (SO group), ischemia-reperfusion group (I/R group) and ulinastatin group (UTI group). Liver in I/R group underwent 1 h of reperfasion after 30 min of ischemia. In UTI group, UTI (2×104 U/kg) was administered to rats 30 min before modeling. The levels of alanine aminotransferase, aspartate aminotransferase and tumor necrosis factor-alpha (TNF-α) in serum were measured and the levels of nitric oxide and malondialdehyde in liver were determined. The histological changes of liver were observed. Results The levels of alanine aminotransferase, aspartate aminotransferase and TNF-α in serum were significantly increased in I/R group compared with those in UTI group (P<0.05). The levels of nitric oxide and malondialdehyde in liver were significantly higher in I/R group than in UTI group (P<0.05).Histological examination of liver indicated that the damages were more severe in I/R group than in UTI group.Conclusion UTI has the ability to inhibit the production of TNF-α and oxyradical, and ameliorate microcirculatory dysfunction in rats with hepatic ischemia-reperfasion injury.     

混凝土连续梁箱形输水桥日照温度应力分析

根据混凝土箱形输水桥的温度边界特点,给出了箱形输水桥日照温差二次曲线分布形式;针对该日照温度梯度模式,按照温度自约束应力的平衡特点和等效线性化的原则,导出了混凝土箱形输水桥的温度应力计算公式和等效线性化后的特征参数计算公式.对某水库输水桥的计算表明:日照作用下混凝土连续梁箱形输水桥中跨截面下缘将产生较大的拉应力,会降低截面抗裂性,应加强纵向预应力钢筋,提高其抗裂能力.     

旧水泥混凝土路面加铺沥青路面的施工技术

反射裂缝是旧水泥混凝土路面上加铺沥青路面的关键问题。在补强处理后旧水泥混凝土路面上加铺玻璃纤维格栅是防止反射裂缝的有效措施。从玻璃纤维格栅的基本性能出发,分析了玻璃纤维格栅防止反射裂缝的机理。对施工中旧路病害调查与评定、路面病害处理、浇洒透层油、铺设玻璃格栅、沥青路面摊铺与碾压等施工工艺进行了详细介绍。     

七里河大桥主墩承台大体积混凝土的施工控制

七里河大桥主墩承台承受着主跨全部的荷载，其安全性和耐久性非常重要。因此，为保证主墩承台的施工质量，必须采用科学的施工方法，进行严密的施工控制，尽量降低混凝土的水化热，减轻或者避免温度裂缝。     

254例糖尿病患者的死因分析

目的分析糖尿病(DM)死亡原因,为防治提供依据。方法回顾性分析西安交通大学医学院第一、二附属医院自1991年1月1日至2003年12月31日期间住院的DM死亡病例。结果13年两院DM死亡254例,占住院总死亡人数3.2%;死因依次为:慢性并发症42.5%(心脑血管病28.3%,肾病14.2%),肿瘤20.1%,感染11.4%,急性并发症6.7%,肝硬化6.3%;慢性并发症死因中合并高血压66.7%(72/108)。结论慢性并发症已成为DM的主要死因,其中心脑血管病变是最重要的,高血压是增加其死亡率的主要危险因素。因此,严格控制血糖和血压,对降低DM心脑血管病变的病死率有重要意义。     

智能化技术在汽车振动控制中的应用现状与发展

智能控制在性能上优于传统控制,目前得到了广泛的应用。本文综述了智能控制在汽车振动控制中的应用,讨论了汽车振动智能控制的未来发展方向。     

空中目标威胁估计的模糊聚类方法研究

依据雷达工作特点和空中目标的具体情况,建立了描述空中目标威胁特性的共性指标体系,应用模糊聚类分析理论,提出了一种基于模糊动态聚类图来判别空中目标威胁程度的方法,并给出实例分析,以验证方法的可行性和有效性.结果表明,案例分析结论与实际情况吻合.     

Survey on arteriovenous fistula in maintenance hemodialysis patients with type 2 diabetic nephropathy

This paper summed up the characteristics of native arteriovenous fistulas (AVFs) in maintenance hemodialysis patients with type 2 diabetic nephropathy (DN) in Chinese hemodialysis centers. A survey was conducted on AVF in maintenance hemodialysis patients with type 2 DN. A total of 224 cases of maintenance hemodialysis patients were included in this study, among which, 65 cases in DN group, 33 cases in diabetes mellitus (DM) group and 126 cases in non-diabetic control (C) group. Hemoglobin, albumin, blood urea nitrogen, parathyroid hormone and calcium-phosphate product of the three groups of patients were not significantly different. Glycated hemoglobin A1c of DN group and DM group was not significant different. AVF life of (28.7 ± 10.0) months in DN group was significantly shorter than that of (36.5 ± 19.4) months in C group (statistic probability P <0.01), and AVF life of (32.5 ± 10.1) months in DM group (P <0.05) was also shorter than that in C group, while there was no significant difference in AVF life between DN group and DM group. Proportion of upper arm fistula in DN patients (11/65) was significantly higher than that in C group (6/123, P < 0.01). Life of AVF in patients with DN was relatively short, with more times of angioplasty and greater possibility of selecting upper arm internal fistula.     

通省隧道云母片岩大变形控制施工技术

通省隧道隧址区主要穿越武当山群地层,岩层结构主要是以含云母为主矿物成份的片岩.在施工过程中隧道围岩岩性与结构多变,强烈的初期支护变形破坏,隧道净空侵限,给施工带来很大的困难,严重制约了工程进度.针对通省隧道地质特点,介绍了在施工过程中对云母片岩大变形的施工防控措施,实现了类似围岩的安全快速施工.     

近40年来中日海上交流研究综述与展望——以跨国人物为主线

中国的日本研究在明代、近代、现代出现过三次高潮,近40年来经过学习、追赶、创新的多个阶段,在局部的“点”甚至特定的“面”上,实现对日本的超越。中日文化交流史是一门新兴的交叉学科,不仅内涵丰富而且外延宽广,但文化的创造、传承、流播、接受、模仿、改良、创新诸环节,均离不开“人”的主导作用。基于此,本文以“跨国人物”为线,从“赴日中国人研究”“来华日本人研究”两个层面,概述近40年来中日海上交流领域所取得的研究成就,突出中国学者的创新点与前沿性,同时指出存在的问题与努力的方向。