厂区道路路面养护方案选择方法研究

以宝钢厂区道路养护管理为背景,针对厂区道路在路面养护方案选择中存在的问题,对厂区道路路面养护工程进行分类和定义,并结合路面管理系统提出养护方案选择的流程与方法,以实现科学制定养护方案和合理分配有限资源的目的.     

市域城市轨道交通及其主要技术特征

介绍了日本、德国、法国等国外典型市域快速线概况及我国市域线概况.分析了市域线的主要功能定位和起源.阐述了市域线对城市形态的影响,以及市域线与一般轨道交通主要技术特征的比较.结合上海市轨道交通线网规划和9号线等工程实际情况,对市域线的主要技术标准进行了探讨.     

水中悬浮隧道管段接头的力学特性分析

文章通过解析方法和数值方法对悬浮隧道管段接头的力学特性进行了分析,旨在探讨影响管段接头力学特性的因素和规律,同时对两种方法进行了分析和比较.     

高烈度地震区公路隧道洞口段地震响应分析

根据隧道地震安全性评价报告和地勘资料,建立了三维数值计算模型并采用一致粘弹性人工边界模拟动力边界,对高烈度地震区公路隧道洞口段进行了瞬态动力计算。计算结果表明:在三向地震荷载激励下,洞口段衬砌的地震响应具有明显滞后性,衬砌以水平横向振动为主、轴向振动次之、竖向振动最弱;洞口段衬砌的拱腰部位将承受极大拉应力和剪应力,可设减震层吸收地震能量。通过对衬砌相对位移的分析得出,衬砌横向和轴向变形都很小,衬砌稳定性尚好。     

浅埋铁路隧道松动土体力学行为分析

采用有限差分软件,对不同围岩、不同埋深的单线和双线电化铁路隧道进行了数值模拟,对围岩松动土体的力学行为进行研究,得出松动土体的破坏范围,并与理论解进行比较.得出结论:朗肯解与规范解分别反映单线和双线电化铁路隧道松动土体的破裂角;破裂角规范解对围岩参数的变化不敏感;隧道跨度对松动土体的破坏范围有重大影响.     

Improvement of the second order approximation of the smoothed particle hydrodynamics

The smoothed particle hydrodynamics (SPH), as a fully Lagrangian particle method, has been successfully applied to astrophysical problems and extended to elastic dynamics and computational fluid dynamics.High order derivatives have to be approximated when elastic dynamics problems are modeled. However, the approximation errors in SPH could lead to computational failure in the case that the order of derivative is high.A novel method was proposed in order to improve the accuracy of SPH method, which shows the relationship between the selected functions and their SPH approximations. The entire involved system was represented by a finite number of particles that carry individual mass and occupy individual space, and the integral interpolation was approximated by a summation interpolation. In addition, error comparison was made between SPH method with and without the present improvement.     

Energy-aware load-balaning fault-tolerant routing scheme for ad hoc sensor networks

Most routing protocols for sensor networks try to extend network lifetime by minimizing the energy consumption, but have not taken the network reliability into account. An energy-aware, load-balancing and fault-tolerant routing scheme, termed as ELFR was propsed to adapt to the harsh environment. First a network robustness model was presented. Based on this model, the route discovery phase was designed to make the sensors to construct into a hop-leveled network which is mesh structure. A cross-layer design was adopted to measure the transmission delay so as to detect the failed nodes. The routing scheme works with acknowledge （ACK） feedback mechanism to transfer control messages to avoid producing extra control overhead messages. When nodes fail, the new healthy paths will be selected locally without rerouting. Simulation results show that our scheme is much robust, and it achieves better energy efficiency, load balancing and maintains good end-to-end delay.     

高职公共英语教学中学生信息素质培养

信息素质是人才综合素质的重要内容之一,因此学生信息素质的培养是当前教育部门必须承担的重要任务和社会责任。以培养应用型人才为目标的高等职业院校责无旁贷。本文通过信息素质这一概念的引入,介绍信息素质培养的主要内容,调查和分析了高等职业院校学生信息素质的现状,从公共英语教学这一特定角度探讨了学生信息素质培养的方法及途径。     

AQP4在COPD支气管黏膜的表达及其与患者肺功能、气道黏膜炎症的相关性

目的通过免疫组化法检测支气管黏膜中水通道蛋白-4(aquaporin-4,AQP4)的表达,观察正常组和慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)组支气管黏膜中AQP4表达与气道黏膜炎症及肺功能的关系,明确AQP4在COPD发生、发展中的作用,为COPD的防治开辟新途径。方法选择正常人和COPD患者各30例,测试肺功能,并行支气管镜检查,取得支气管黏膜标本,用免疫组化法检测AQP4表达,HE染色观察支气管黏膜炎症细胞浸润程度。结果COPD组较对照组AQP4表达减弱有极显著差异(P<0.001)。AQP4表达和FEV1/FVC、FEV1/pred%呈正相关(P<0.001),与支气管黏膜炎症严重程度呈负相关(P<0.001)。结论COPD患者AQP4表达减少可能是其肺功能下降及气道炎症加重的原因之一。临床上可以通过改善AQP4治疗COPD。     

多房棘球绦虫重组Bb-Em14-3-3疫苗的构建及其表达效率

目的构建多房棘球绦虫(Em)重组双歧杆菌(Bb)-Em14-3-3疫苗,并研究Em14-3-3分子在大肠埃希菌BL21(DE3)中的表达效率。方法通过PCR扩增Em14-3-3抗原编码基因;将该基因定向克隆于含有谷胱甘肽-S-转移酶(GST)基因的大肠埃希菌-双歧杆菌穿梭表达载体pGEX-1λT,构建重组质粒pGEX-Em14-3-3;用电穿孔法将该质粒导入Bb,构建多房棘球绦虫重组Bb-Em14-3-3疫苗。经PCR和酶切鉴定后以IPTG诱导表达Em14-3-3/GST融合蛋白;SDS-PAGE及Western blot对表达产物进行鉴定。结果PCR成功扩增出530 bp的Em14-3-3基因;双酶切证实Em14-3-3基因插入pGEX-1λT中;PCR证实重组Bb-Em14-3-3疫苗构建成功;SDS-PAGE及Western blot分析显示重组质粒转化宿主菌在IPTG诱导下高效表达了Em14-3-3/GST融合蛋白,表达效率为23%。结论成功构建了多房棘球绦虫重组Bb-Em14-3-3疫苗,重组质粒pGEX-Em14-3-3在大肠杆菌中获得了高效表达,Western blot结果提示表达出的Em14-3-3重组蛋白具有特异抗原性。