西康铁路增建第二线岩溶问题概述

西安安康铁路柞水以南分布石炭系、泥盆系和寒武--奥陶系灰岩,增建二线工程会遇到大量的岩溶问题.对沿线岩溶形成机理、发育特征进行了论述,结合西康二线平纵断面设计,对沿线岩溶发育强度进行了垂直和水平分带,并对岩溶危害程度最大的隧道工程提出了施工方法和安全施工要求的建议.     

股权分置改革对股利政策的影响预估

随着股权分置改革的推进，我国上市公司国有股股权比例会经由全流通而降低，通过对我国分红与不分红上市公司盈利能力、流通股东对分红公司的偏好以及上市公司股权结构与分红倾向三方面的实证，探讨股权结构的分散化将对我国上市公司股利政策产生的影响，提出了股权分置改革后，我国上市公司分红倾向很可能与广泛预期相反，呈下降态势。股权分置改革对股利政策的影响预估     

逆转录病毒介导CXCR4-siRNA对前列腺癌细胞体外侵袭能力的影响

目的设计构建趋化因子受体4(CXCR4)的RNA干扰逆转录病毒载体,探讨干扰CXCR4表达对前列腺癌细胞侵袭能力的影响。方法用PCR扩增CXCR4特异性小干扰RNA(smallinterferingRNA,siRNA),转入带有增强型绿色荧光蛋白(EGFP)和启动子U6的Pgensil-1质粒中,再将重组基因片段导入到逆转录病毒真核表达载体PLX-SN中,行限制性酶切及测序鉴定。重组逆转录病毒载体转染包装细胞PA317,获取病毒上清转染前列腺癌细胞,RT-PCR检测CXCR4mRNA表达。Transwell小室侵袭实验检测前列腺癌细胞体外侵袭能力的变化。结果通过酶切及测序鉴定,成功构建了PLXSN/EGFP-U6-siCXCR4。干扰质粒抑制CXCR4mRNA的表达,与空载体组比较,PC-3m、LNCaPsiRNA对CXCR4mRNA的抑制率分别为(84.26±10.20)%和(88.17±11.23)%。Transwell侵袭实验结果显示,干扰组微膜下孔细胞数PC-3m、LNCaP分别为(14.7±3.1)和(18.9±4.2)个,空载体组分别为(46.9±5.3)和(66.7±6.0)个,两者差异显著(P<0.05)。结论PLXSN/EGFP-U6-siCXCR4可以有效地抑制前列腺癌细胞CXCR4mRNA的表达,干扰CXCR4可以显著抑制前列腺癌细胞体外侵袭转移能力。     

“心肌荣”口服液对充血性心力衰竭患者的急性血液动力学效应

分组观察＂心肌荣＂口服液对３２例慢性充血性心力衰竭（ＣＨＦ）患者的急性血液动力学效应。结果表明：口服＂心肌荣＂４０、１００ｍｌ组，在服药后平均肺动脉压（ＭＰＡＰ）、肺楔压（ＰＷＰ）明显下降，而心脏指数（ＣＩ）明显上升（Ｐ＜０．０５），此作用维持４ｈ，提示口服＂心肌荣＂４０ｍｌ，每天３次，可治疗在性ＣＨＦ．     

板梁桥在特种车辆荷载作用下的结构检测与评估

通过对桥梁在特种车辆荷载作用下的结构响应监测和理论计算分析,发现特载对该板梁桥造成的主要损害是削弱了板梁间的联结强度。最后按照相关规范对该桥在经历特种荷载后的技术状况进行了评定。     

政府工程采购的发展情况及存在问题

政府采购机制是规范化我国政府投资建设项目管理的一个重要工作领域。文章针对我国政府采购和政府工程采购的基本发展情况进行了说明,并对政府工程采购发展过程中存在的主要问题进行了分析。     

空车调整最小费用的合理分摊

借助多人合作对策的思想建立了铁路空车调整问题中最小费用合理分摊的数学模型，给出了建立理想分摊向量和特征函数的一种方法，并提供了具体解法，比较有效地解决了空车调整中最小费用的合理分摊问题，为最优调运方案的实际实施提供了前提和保障。     

The speed control effect of highway tunnel sidewall markings based on color and temporal frequency

The low‐luminance monotonous environment in the middle section of highway tunnels offers few reference points and is prone to cause severe visual illusion. Thus, drivers tend to underestimate their driving speed, which can induce speeding behaviors that result in rear‐end collisions. Therefore, discovering low‐cost methods of traffic engineering that reduce this visual illusion and ensure a steady driving speed is an important challenge for current highway tunnel operations. This study analyzes the effects of sidewall markings in typical highway tunnels, specifically observing how their colors and temporal frequencies affect the driver's speed perception in a low‐luminance condition. A three‐dimensional model of the middle section of highway tunnels was built in a driving simulator. Psychophysical tests of speed perception were carried out by the method of limits. The precision of the simulation model was then checked by comparing the results to field test data. The simulation tests studied the stimulus of subjectively equal speed and reaction time in relation to sidewall markings in different colors (red–white combined, yellow–white combined, and blue–white combined). Furthermore, based on the optimal color, the effects of sidewall marking with different temporal frequencies (0.4, 0.8, 1.2, 2, 4, 8, 12, 16, and 32 Hz) on the speed perception of drivers were also analyzed. The test results reveal that the color and temporal frequency of sidewall marking have a significant impact on the driver's stimulus of subjectively equal speed and reaction time. The subjects have the highest speed overestimation and an easy speed judgment with the red–white combined sidewall marking. Within the temporal frequency range of 4.45–7.01 Hz, the subjects have a certain degree of speed overestimation (less than 20%), and the speed perception is sensitive to the temporal frequency changes. Copyright © 2016 John Wiley & Sons, Ltd.     

Design and power flow analysis for multi-speed automatic transmission with hybrid gear trains

A design approach for multi-speed automatic transmission with hybrid gear trains is proposed. The approach can be used to design automatic transmissions composed of planetary gear trains, fixed-axis gear trains or hybrid gear trains and the shifts follow the “one controlled part changing rule”. This approach consists of four parts: determining graphical configuration of the system using hypergraphs, analyzing power flow formulation, obtaining shifts configurations by shift searching algorithm, and determining physical configuration. A nine forward speed automatic transmission is analyzed to highlight the capacities of the proposed approach. The results have shown that the suggested approach is much clearer and less time consuming than the methods currently used.