Fine Mapping of a Deafness Mutation hml on Mouse Chromosome 10

Objective To map a mouse deafness gene.identify the underlying mutation and develop a mouse model for human deafncss.Methods Genetic lindage cross and genome scan wer used to map a novel mutation named hypoplasia of the membranous labyrinth (hml),which causes hearing loss in mutant mice.Results ① hml was mapped on mouse Chr 10 (～43 cM from the centromere) suggests that the homologous human gene is on 12q22--q24, which was defined on the basis of known mouse-human homologies (OMIM,2004). ② This study has generated 25 polymorphic microsateUite markers, placed 3 known human genes in the correct order in a high-resolution mouse map and narrowed the hml candidate gene region to a 500 kb area.     

康明斯涡轮增压技术系统迎来在华发展新高潮

2008年6月11日,随着无锡康明斯涡轮增压技术公司(原无锡霍尔塞特)二期新厂房正式落成、无锡范尼韦尔工程公司开业投产以及康明斯涡轮增压技术系统新技术中心正式揭牌,康明斯涡轮增压技术系统(康明斯公司全资子公司)在华本地生产和研发能力得到新的提升.     

LEISHMANIA PROMASTIGOTES EVADE INTERLEUKIN 12 INDUCTION BY MACROPHAGES AND STIMULATE A BROAD RANGE OF CYTOKINES FROM CD_（4）~（＋

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REGULATION OF PRODUCTION OF PARATHYROID HORMONE－RELATED PEPTIDE （PTHrP） AND EXPRESSION OF ITS mRNA IN A HUMANLIVER－DERIVED CE

ＲＥＧＵＬＡＴＩＯＮＯＦＰＲＯＤＵＣＴＩＯＮＯＦＰＡＲＡＴＨＹＲＯＩＤＨＯＲＭＯＮＥ－ＲＥＬＡＴＥＤＰＥＰＴＩＤＥ（ＰＴＨｒＰ）ＡＮＤＥＸＰＲＥＳＳＩＯＮＯＦＩＴＳｍＲＮＡＩＮＡＨＵＭＡＮＬＩＶＥＲ－ＤＥＲＩＶＥＤＣＥＬＬＬＩＮＥＬｉＨｕｓｏｎｇ；Ｐ...     

TRANSCRIPTION ACTIVATION BY HBV PRE SI PROTEIN

ＴＲＡＮＳＣＲＩＰＴＩＯＮＡＣＴＩＶＡＴＩＯＮＢＹＨＢＶＰＲＥＳＩＰＲＯＴＥＩＮＸｉａｏＳｈｅｎｇｘｉａｎｇ；Ｔ．Ｓ．Ｂ．Ｙｅｎ（ＬａｂｏｒａｔｏｒｙｏｆＭｏｌｅｃｕｌａｒＰａｔｈｏｌｏｇｙ，ＤｅｐａｒｔｍｅｎｔｏｆＰａｔｈｏｌｏｇｙ，Ｕｎｉｖ．ｏｆ...     

台北公共交通月及无车日活动回顾与展望

台北国际无车日自2002年起举办了5次,由最早的骑自行车活动扩大至包含“走路上学日”与“公共交通月”丰富多彩的系列活动,渐渐获得民众认同。无车日活动的目标是通过活动的倡导和社会参与来改变民众使用交通工具的行为,潜移默化的效应可促使形成可持续交通政策,当可持续交通政策与基础设施建设落实后又可具体改变交通环境,形成良性的循环机制。首先说明了“无车日”的由来,并回顾台北都会区过去5年来举行无车日系列活动的内容与经验,同时基于活动的发展与成果归纳出无车日活动的成功要素,最后提出未来活动将扩大举办的内容、方式与展望,以期能为其他城市作参考。     

RECENT DEVELOPMENT OF PROCESS SIMULATION AND ITS APPLICATIONS TO MANUFACTURING PROCESSES

l.IntroductionThemostboortantdrivingforceinmanufacturillistoPrOduCeabetterPrOductatalowercost.GenerallyeffecthemethodsinchideshOrtenintheleadtiminthedesigncyCle,andredUcinthetoolingcostandmaChinedOWnmeatProductionst4e.AllOfthemrewtabettertmderstandingofhO…