肾康注射液对高血压肾损害大鼠血压及相关指标的影响

目的探讨肾康注射液对高血压肾损伤大鼠血压及相关指标的影响。方法将32只高血压肾损伤模型大鼠随机分为4组:模型对照组(即SHR组)、阳性对照组、肾康注射液大剂量组、肾康注射液小剂量组;WKY大鼠作为阴性对照组。阳性对照组腹腔注射给予福辛普利钠1.6mg/kg,肾康注射液大小剂量组分别腹腔注射肾康注射液,相当于生药剂量为4.8、2.4g/kg,阴性对照组和模型组腹腔分别注射等体积生理盐水,每天1次,连续给药30d。末次给药后检测高血压肾损伤大鼠的血压、心脏病变以及NO、Ang-Ⅱ、C反应蛋白、TGF-β1等指标。结果给药前后各组间大鼠体质量无明显差异(P>0.05);给药后肾康注射液组的血压值明显低于模型对照组,差异具有统计学意义(P<0.05或P<0.01);与模型对照组比较,肾康注射液组的NO活性明显增高,肾脏皮质中的Ang-Ⅱ明显降低,C反应蛋白明显降低,差异有统计学意义(P<0.05);但血清中的Ang-Ⅱ、血清转化因子TGF-β1无显著性差异(P>0.05)。结论肾康注射液能降低高血压肾损伤大鼠血压、提高肾组织的NO活性、降低Ang-Ⅱ及C反应蛋白的含量。     

钢筋混凝土偏压构件抗力的时变规律

现有钢筋混凝土构件的抗力时变模型,多是关于仅受弯的梁式构件,对偏压构件的考虑较少.针对此不足,首先分析了影响偏压构件抗力的各因素的时变模型.在此基础上,计算了不同参数情形下偏压构件抗力退化的若干数值特征,得出钢筋锈蚀后偏心距较大时抗力均值的下降程度会大一些,同时整个服役期内偏压构件的破坏模式可能会发生改变的结论.最后采...     

PC斜拉桥辅助墩摆索拉力支座恢复加固施工控制分析

以某PC斜拉桥维修工程为背景,用GQJS软件进行斜拉桥加固维修施工控制的模拟计算分析,其中包括根据全桥拉索索力、桥面线形、塔位、主梁混凝土应力和支座工作状态等结构参数的监测结果模拟结构的实际状态,根据桥梁结构的病害状况对结构参数进行修正.介绍了摆索拉力支座恢复的施工方法,以及结构在摆索拉力支座恢复过程中的结构力学性能变...     

Multi-state control strategy of starting for a wet friction clutch via a fuzzy logic algorithm

Wet multi-plate friction clutches are used in automotive drivelines to transfer torque, change gears, and prevent motion by locking-up components in the transmission. The control strategy of starting is a crucial technology for the application of a wet multi-plate friction clutch in the automotive industry. In this paper, a multi-state fuzzy control strategy for starting is presented and applied to a continuously variably transmission (CVT) powertrain for the validation of this strategy. The operation of the clutch was divided into four states: parking, starting, riding and emergency. The starting state was investigated in detail. A fuzzy algorithm was employed to control the pressure of the hydraulic cylinder acting on the clutch. A distinguishing feature is that the pressure does not increase but decreases to implement smooth starting during the initial period of starting. The rapid-control prototype (RCP) of the wet friction clutch was developed to validate the new control strategy onboard a test vehicle. Based on the experimental results, the multi-state control strategy for a wet friction clutch is a viable candidate for engineering applications.     

Model referenced adaptive control to compensate slip-stick transition during clutch engagement

Clutches are widely used in various vehicle powertrains. The engagement process of a friction clutch has three phases, i.e., open, slipping, and sticking. Transitions between different phases introduce a discontinuity to the powertrain dynamics, which has been neglected in previous research. A model referenced adaptive controller (MRAC), based on Popov hyper-stability criterion, is designed to compensate the discontinuity. MRAC adjusts the frictional torque along with the errors of the state variables compared with those of a referenced model. The designed MRAC is applied to a clutch in a bus. Simulation and experimental results under fast and slow startup cases show that MRAC can simultaneously reduce vehicle jerk and frictional dissipation when compared with the conventional controller.     

正面碰撞试验后排女性假人伤害研究

通过实车碰撞试验,对假人伤害数据进行分析,对比研究后排假人伤害的特点,并讨论造成前后排假人伤害差异的原因,对于促进和提高车辆被动安全性能具有十分重要的意义。     

磁浮轨道定子线圈限界监测系统设计

磁浮轨道定子线圈限界监测系统能进一步保障磁浮列车的行车安全。通过对磁浮轨道定子线圈结构特点的研究,选择符合需求目标的检测原理和实现方法,并详细描述系统构成、软件硬件系统及辅助系统等关键问题,实际使用证明其原理正确,方法可行,能达到预期的设计目标。     

基于ANSYS的小半径陡坡路段混凝土面板受力分析

山区农村公路具有半径小、纵坡大的特点,如何避免山区农村公路水泥混凝土路面提前破坏,确保其达到设计使用寿命,减少养护维修费用,已成为目前山区农村公路水泥混凝土路面修建面临的重要课题。采用三维动态有限元,分析计算小半径与陡坡组合路段路面板底最大拉应力、最大剪应力,并与直线路段和平坡路段下的相应状态进行比较,得到陡坡急弯路段路面力学响应的特点。     

一级公路双侧辅道沥青路面质量监控

详细阐述第三方质量监控的必要性、内容和工作重点,结合广州省某一级公路双侧辅道沥青路面质量监控工程,对施工过程中应重点监控的指标进行应用举例,并分析监控过程中遇到的一些问题。     

伊辛模型实现量子态存储和调节

考虑利用腔QED理论模拟伊辛模型,双原子在腔中演化之后,可以实现特定量子态的稳定存储,调节相互作用时间和外驱动场的频率可以实现最大纠缠态的制备.