REGULATION OF PRODUCTION OF PARATHYROID HORMONE－RELATED PEPTIDE （PTHrP） AND EXPRESSION OF ITS mRNA IN A HUMANLIVER－DERIVED CE

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Roll Dynamics of Commercial Vehicles

An analytical model is developed here for studying the roll dynamics of commercial vehicles. Large displacements and rotations are accounted for in this nonlinear model so that it can be used for the study of roll dynamics well beyond the limits of wheel lift-off. The model is used to illustrate some of the dynamic phenomena in vehicle rollover, especially the interactive coupling between the roll and the vertical modes of motion. The influence of suspension backlash on rollover resistance is demonstrated, and the phenomenon of roll motion resonance is illustrated to suggest new means for evaluating vehicle rollover sensitivity.     

The dynamic relationships between paper petroleum refining and physical trade of crude oil into the United States

This article examines the relationship between refinery margins traded on paper using petroleum futures (the paper refinery) and the physical trade of crude oil into the US. Computations of a 3:2:1 crack spread were constructed using daily observations of second- and third-nearby unleaded gasoline and heating oil futures contracts traded on the New York Mercantile Exchange (NY MEX) and spot Brent crude oil prices. The crack spread represents the margin between the cost of crude oil feed stock today and the value of the products produced by a refinery in the future. Unit root tests on each of the time series found crack spreads to be stationary while crude oil imports were found to be non-stationary. A s the two series were found to be integrated of different order, cointegration analysis of the two series was not deemed appropriate. Instead, linear relationships between crack spreads and imports were examined using causality tests. It was found that the 2-month 3:2:1 crack spread Granger-causes crude oil imports and that this causality is unidirectional. The significance of these findings lies in the fact that other industries like tanker shipping derive their demand from the demand for, and trade in, petroleum. Crack spreads, therefore, can provide a leading indicator for short term developments in tanker demand. For a chartering manager who has ships on the spot market, crack spreads can help him/her anticipate demand developments and influence vessel deployment and chartering decisions.     

Driver fatigue: a vision-based approach to automatic diagnosis

In this paper, we describe a system that locates and tracks the eyes of a driver. The purpose of such a system is to perform detection of driver fatigue. By mounting a small camera inside the car, we can monitor the face of the driver and look for eye movements which indicate that the driver is no longer in condition to drive. In such a case, a warning signal should be issued. This paper describes how to find and track the eyes. We also describe a method that can determine if the eyes are open or closed. The primary criterion for this system is that it must be highly non-intrusive. The system must also operate regardless of the texture and the color of the face. It must also be able to handle changing conditions such as changes in light, shadows, reflections, etc. Initial experimental results are very promising even when the driver moves his/her head in a way such that the camera does not have a frontal view of the driver’s face.     

The Demise of a Tropical Coastal Lagoon as Breeding Habitat for Ground-Nesting Waterbirds: Unintended,but Anticipated Consequences of Development

Laguna Cuyutlán (Colima, Mexico), an Important Bird Area, used to provide breeding habitat for ground-nesting waterbirds. During 2014 and 2015, nesting efforts of laughing gull, black skimmer, and royal, gull-billed and Forster's terns failed almost completely due to inundation, while least terns and snowy plovers fared the same during 2014. No anomalies in rainfall, tidal level, or coseismic subsidence explained such failure. Rather, the inundations were due to the enlarging of Canal Tepalcates that connects the lagoon with the sea, which was widened from 100 to 300 m and dredged to 17-m deep. Before this, the hydrodynamics were regulated by evaporation and runoff. Now, increased seawater volumes dominate the basin's hydrodynamics. The failure of Laguna Cuyutlán as a breeding habitat for these birds is an important threat for these species, as this lagoon held one of the < 20 colonies known for several of these species along the western coast of North and Central America. Documenting this demise of Laguna Cuyutlán for ground-nesting waterbirds transcends the regional scale as it emphasizes the little consideration still given to biodiversity vs. economic development, and is a warning for coastal projects in other developing areas of the world.     

Estimating travel time functions for urban roads: options and issues

Travel time functions specify the relationship between the travel time on a road and the volume of traffic on the road. Until recently, the parameters of travel time functions were rarely estimated in practice; however, a compelling case can be made for the empirical examination of these functions. This paper reviews, and qualitatively evaluates, a range of options for developing a set of travel time functions. A hierarchy of travel time functions is defined based on four levels of network detail: area, corridor, route and link. This hierarchy is illustrated by considering the development of travel time functions for Adelaide. Alternative sources of data for estimating travel time functions are identified.

In general, the costs and benefits increase as the travel time functions are estimated at finer levels of network detail. The costs of developing travel time functions include data acquisition costs and analysis costs. The benefits include the potential for reducing prediction errors, the degree of application flexibility and the policy sensitivity of the travel time functions.