Are millennials more multimodal? A latent-class cluster analysis with attitudes and preferences among millennial and Generation X commuters in California

Transportation - Millennials tend to use a variety of travel modes more often than older birth cohorts. Two potential explanations for this phenomenon prevail in the literature. According to the...     

The role of intention as mediator between latent effects and behavior: application of a hybrid choice model to study departure time choices

Transportation - An increasing number of papers are focusing on integrating psychological aspects into the typical discrete choice models. The majority of these studies account for several latent...     

磨粒的三维测量与重构

在铁谱分析中引入计算机三维测量与重构技术,通过使用改进拉普拉斯算子对在普通光学显微镜下拍摄到的磨粒连续图像序列进行清晰度分析来测量磨粒表面高度,重构磨粒三维图像.在普通光学显微镜下快速、方便地获取磨粒表面三维图,使铁谱分析技术不再仅限于对磨粒图像的二维分析.     

Improvement of efficiency and flexibility in multi-slice helical CT

One of the main aspects in computed tomography (CT) development is to make CT rapidly scan a large longitudinal volume with high z-axis resolution. The combination of helical scanning with multi-slice CT is a promising approach. Image reconstruction in multi-slice CT becomes, therefore, the major challenge. Known algorithms need to derive the complementary data or work only for certain range of pitches. A reconstruction algorithm was presented that works with the direct data as well as arbitrary pitches. Filter interpolation based on the proposed method was implemented easy. The results of computer simulations under kinds of conditions for four-slice CT were presented. The proposed method can obtain higher efficiency than the conventional method.     

Energy-saving reputation method for wireless sensor networks

Reputation mechanism has been recently introduced into wireless sensor networks (WSNs) to overcome the deficiencies incurred by cryptography alone. Unlike most current reputation mechanisms that are based on binomial distribution and to some extent, do not give due attention to the aspect of energy constraint of WSNs, this research deduces and proves the feasibility that negative binomial distribution can well be used in the reputation update with distinctive energy-saving features. Comparison tests with respect to the energy consumption in terms of reputation computing frequencies are done between the traditional reputation method and the one in this study. Results show that our method can save more energy for the reputation update and thus can better meet the power constraints of WSNs.     

Fine Mapping of a Deafness Mutation hml on Mouse Chromosome 10

Objective To map a mouse deafness gene.identify the underlying mutation and develop a mouse model for human deafncss.Methods Genetic lindage cross and genome scan wer used to map a novel mutation named hypoplasia of the membranous labyrinth (hml),which causes hearing loss in mutant mice.Results ① hml was mapped on mouse Chr 10 (～43 cM from the centromere) suggests that the homologous human gene is on 12q22--q24, which was defined on the basis of known mouse-human homologies (OMIM,2004). ② This study has generated 25 polymorphic microsateUite markers, placed 3 known human genes in the correct order in a high-resolution mouse map and narrowed the hml candidate gene region to a 500 kb area.     

EFFECTS OF OUABAIN AND DIGOXIN ON THE GENE EXPRESSION OFSODIUM PUMP α-SUBUNIT ISOFORM IN AORTIC SMOOTH MUSCLE OF RATS

Accumulating evidence indicates that endoge-nous ligands of the digitalis receptor may exist inthe mammalian body, which has recently been de-scribed to be indistinguishable from ouabainL1'2j.Endogenous ouabain (EO) might induce many cy-tobiological changes and play an important role inregulating water and sodium metabolism and vas-cular tone in the body["'J. Many studies haveshowed that EO content in both hypertensive pa-tients and hypertensive animals is much more thanthose of normal subje…     

肿瘤免疫研究的回顾与展望

20多年来,本校免疫病理研究室一直从事肿瘤免疫的研究,从研究肿瘤浸润淋巴细胞的活化和肿瘤逃逸的机制开始,到探索诱导浸润淋巴细胞(tumor infiltrating lymphocytes, TIL)活化的最佳条件,并将这些研究结果转化为肿瘤免疫治疗和免疫预防的实践,从一个侧面反映了人类在征服肿瘤道路上的艰苦历程。     

异丙酚对兔肝缺血再灌注损伤时内皮素-1和一氧化氮的影响

目的探讨异丙酚对兔在体肝缺血再灌注损伤时内皮素-1(ET-1)和一氧化氮(NO)的影响。方法40只家兔随机分为4组,每组10只,分别为缺血再灌注组(A组)、缺血再灌注加生理盐水2 mL/(kg.h)组(B组)、缺血再灌注加异丙酚8mg/(kg.h)组(C组)和假手术对照组(D组)。各组于再灌注后306、0 min测定肝组织和血浆中ET-1与NO水平以及血清谷丙转氨酶(ALT)、谷草转氨酶(AST)的水平,并进行肝组织形态学观察。结果与D组比较,A、B、C组于再灌注后30 min及60 min时,肝组织和血浆中ET-1均呈上升,但C组的上升程度明显低于同时间点的A、B两组(P<0.01);同时肝组织和血清中NO呈下降,但C组的下降程度明显低于同时间点的A、B两组(P<0.01);血清ALT、AST均升高,但C组的升高程度明显低于同时间点的A、B两组(P<0.01);肝细胞形态学发生异常改变,C组的肝脏淤血明显较A、B两组轻,肝细胞变性坏死不明显。结论异丙酚通过保护肝窦内皮,降低机体内ET-1水平,提高NO水平,改善肝脏微循环障碍,对HIRI有保护作用。     

基于频域法的结构疲劳寿命预测方法研究

以Didik方法的雨流循环计数应力范围概率密度函数为依据，考虑长寿命区的S-N曲线，利用不完全Γ函数建立了一种宽带随机载荷谱下结构疲劳寿命计算的解析解法，为用频域法计算结构在宽带随机载荷谱下疲劳寿命提供了一种快捷方法。