Protective effect of glutamine pretreatment on ischemia-reperfusion injury of spinal cord in rabbits

Objective To investigate the effect of glutamine (Gln) on the content of reduced glutathione hormone (GSH) and aminoglutaminic acid (Glu) of spinal cord following ischemia-reperfusion injury. Methods Totally 40 healthy adult male rabbits were randomly divided into five groups: sham-operation group (S group), ischemia-reperfusion injury group (I/R group), low-dose glutamine group (L Gln group), median-dose glutamine group (M Gln group) and high-dose glutamine group (H Gln group). After glutamine preconditioning, the model of spinal cord ischemia-reporfasion injury was established according to Zivin's method. The general status of animals was observed and the changes of Jacobs scoring were recorded in each group. Malondialdehydes (MDA), GSH, Glu and superoxide dismutase (SOD) activity in lumbar spinal cord tissues were determined using chemical colorimetry. The neuron number and deviation rate in spinal cord anterior horn were observed histopathologically. Results There was no significant difference between L Gin group and I/R group in behavior scoring, SOD activity, content of MDA and Glu, neuron number and deviation rate of spinal cord (P>0.05); however, there was a significant difference in GSH content of spinal cord (P<0.05). M Gln group and I/R group differed significantly (P<0.05) in behavior scoring, SOD activity, content of MDA, Glu, GSH, neuron number and deviation rate of spinal cord. Between H Gln group and M Gln group, there was no significant difference in behavior scoring, content of MDA and Glu, SOD activity, neuron number and aberration rate in spinal cord (P>0.05), whereas there was a significant difference in SOD activity and Giu content (P<0.05). Conclusion Pretreatment with medium-dose glutamine has a protective effect on spinal cord ischemia-reporfasion injury in rabbits, which may be related to the maintenance of GSH content, increase of SOD activity and reduction of MDA.     

长寿命路面应力吸收层有限元分析

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解乏操

开车时间长一些,是否觉得腰背僵硬,偶尔还会酸疼?高速路上行车,是否有时会觉得昏昏欲睡,困倦难耐?这些症状经常出现在驾车族的身上,有时候还不得不继续开车赶路,怎么办呢?偶然间,一位资深车友李智教了我一套"解乏操",抱着试试看的态度做了几节,还真挺管用,顿觉神清气爽,疲乏顿消。     

基于关键帧的开环-闭环混合FGS编码框架

为提高FGS的编码效率,提出了一种基于关键参考帧的开环-闭环混合FGS编码框架.对非关键帧采用单预测环路的开环结构,以提高编码效率;周期性地插入一些使用双预测环路闭环结构的关键帧,以控制开环结构导致的预测漂移.此外,为更好地利用带宽,提出了一种相应的码流截取方式,将码率优先分配给对序列整体质量贡献更大的关键帧.实验结果表明,较之JVT SVC中的AR-FGS,混合FGS编码框架在极宽的码率范围内提高了编码效率,PSNR值平均提高了1～2 dB.     

施工过程中筏板基础应力和沉降变化规律

针对国内还没有具体文献详细分析模拟施工过程对筏板基础响应的影响,本文建立上部结构、筏板基础与地基共同作用的模型,利用ANSYS有限元软件自身的单元生死技术,计算分析了施工过程对筏板基础响应的影响.数值分析的结果表明,施工过程只在开始几层施工时对筏板影响较大,随着层数的增加,影响会越来越小.     

＂马太效应＂对科技奖励的影响

科技奖励中的＂马太效应＂具有双重作用,是现代科学技术发展过程中难以避免的客观现象,它既有促进科技进步,形成优势积累等积极作用,又有加剧科学共同体等级分化、阻碍科技新人发现成长及催生学术腐败等消极影响。本文系统分析了科技奖励中的＂马太效应＂的积极作用与消极影响,并提出了相应对策,从而为采取措施,趋利避害,促进科学技术稳定发展提供理论基础。     

水位升降对岩质路基边坡稳定性的影响分析

在沿江、河、湖畔道路及湖泊道路建设中,由于水的作用,地质灾害频繁发生,甚至毁坏道路并造成重大人员伤亡及经济损失.由于道路具有跨区域广及评价面积小的特点,故寻求合理有效的分析理论与方法成为有效控制灾害发生的关键.     

矿渣粉稳定黄土的作用效应与测定方法

结合矿渣粉本身具有的火山灰和超细颗粒性能特点,分析矿渣粉稳定黄土及矿渣粉提高稳定黄土强度的三种作用效应,即火山灰胶凝效应、微集料增强效应和复合效应;结合比强度法,介绍三种效应的试验测定方法,最后提出提高稳定黄土强度的措施。     

天山公路K1018段边坡稳定性数值模拟分析

通过对天山公路K1018＋200-＋800段边坡实地勘察研究．利用数值模拟DDA块体系统的非连续变形分析系统数值分析软件,对边坡不同工况条件下的破坏模式与块体运动特征．进行了稳定性分析。结果表明：诸多不安全因素会影响边坡的稳定,应及时采取措施予以治理。     

安全保护排排坐如何安装儿童安全座椅（之二）

儿童安全座椅对儿童身体各部位都要起到很好的保护作用,所以座椅各部件的调节可直接影响儿童安全座椅安全性的高低。