弹性构架对车辆系统振动响应的影响

为了研究弹性构架对车辆系统振动响应的影响,结合FE软件ANSYS和MBS软件SIMPACK,通过在SIMPACK前处理程序FEMBS中生成弹性构架的标准输入文件,在SIMPACK中建立刚柔耦合的车辆系统动力学模型,并把转向架构架考虑为弹性体.通过仿真计算,获得了车辆系统的位移、加速度、振动频率等振动响应特性.对比分析结果表明,弹性构架对系统的振动响应强于刚性构架,且加宽了系统的振动频率范围.     

基于回流电感应电源的研究与应用

利用电气化铁路架空回流线与大地间的电位差研制的高压感应电源,有效地解决了铁路沿线尤其是隧道内对交流电源的需要,使一些智能监控设备得以在铁路沿线安装使用。介绍回流电感应电源的工作原理、技术参数、性能特点。     

偏振轴非平行的平行波导耦合系数分析

根据耦合模理论推导出适用于纤芯为任意截面形状、两根保偏光纤的偏振轴非平行保偏光纤耦合器的耦合系数计算公式，形式简单、应用方便。     

车辆脱轨的耦合动力学分析

本文应用车辆－轨道系统耦合动力学理论，对车辆经过一段由缓－圆－缓组成的线路进行了车辆的脱轨稳定性分析。通过对车辆在耦合动力学模型与传统车辆动力学模型下脱轨道稳定性之分析比较，指出了进行车辆脱轨的耦合动力学分析必要性。     

非扩张映象的Ishikawa迭代与最佳逼近元

在严格凸Banach空间中研究了非扩张映象T的耦合不动点集F(T)的闭凸性,获得了当F(T)是Hilbert空间中的闭线性子空间时,Ishikawa迭代的极限元与其初始元的最佳逼近元之间的关系.     

无人驾驶技术探秘

现代高利技与汽车技术相结合，已经能够制成多种用途的无人驾驶汽车，供不同行业使用。无人驾驶汽车曾经历了概念研究、模型试验、样车研制、设计定型，小批量生产供货等若干个阶段的发展，方步入实用化的。     

天文星占在北宋皇权政治中的作用

天星占在中国古代皇权政治中起着极为特殊的作用，历代统治往往把其作为一种重要的统治手段来运作。本探讨了天星占在北宋皇权政治中所发挥的作用，认为它是维护皇权正统形象的有效手段，是约束皇权的有力武器，也是左右朝臣进退的重要工具。     

空重车混编对列车稳定性的影响

为了考察空重车混编列车的稳定性,建立了混编列车动力学模型,利用循环变量法解决了列车的"自由度爆炸"难题,利用模块化建模法解决了列车混合编组的建模难题,而且充分考虑了列车纵向、横向和垂向性能之间的耦合关系.利用新型的列车动力学模型,分析了空重罐车各种不同的编组形式对列车稳定性的影响.发现空罐车编组在列车尾部和头部时的稳定性较差,而编组在列车中部时的稳定性较好,因此在空重罐车混和编组时,为了提高列车稳定性,尽量把空罐车编组在列车的中部.     

THE HUMORAL AND CELLULAR IMMUNE RESPONSES INDUCED BY HPV18L1-E6/E7 DNA VACCINES IN MICE

Objective To construct eukaryutic expression vector of HPV18 L1- E6, E7 chimeric gene and examine the humorul and cellular immune responses induced by this DNA vaccines in mice. Methods The C-terminal of major rapsid protein L1 gene and mutant zinc finger domains of early E6/7 oncogenes in HPV18 were integrated and inserted into eukaryotic expression vector pVAX1 to generate vaccines pVAX1-L1E6Mxx, ETMxx. CHO cells were transiently transfected with the individual construct. Target protein expressions in the lysate of the transfected cells were measured by ELISA and immunocytochemistry After BALB/c mice were vaccinated with various recombinant plusmids（pVAX1- L1-E6M3 or pVAX1-L1-E7M3 ） and immunie adjuvants （pLXHDmB7-2 or LTB） through different administration routes （intramuscular or intranasal） , the great cellular immune responses were produced us revealed by delayed-type hypersensitivity （DTH） and lymphocyte proliferation, and the expression of IL-4 and IFN- 7 cells in CD4^＋ and CD8^＋ subpopulations. Results The highly efficient expression of pVAX1-L1E6Mxx, E7Mxx vector in host eukaryotic cells were demonstrated both by ELISA and immunocytochemistry. The level of specific serum IgG against HPV in experiment groups mice was much higher than that of control group, and intranuscular immunization group had the highest antibody level. Intramuscular immunization groups were superior to intranasal immunization groups in DTH response, splenocyte proliferation and CD8^＋ IFN-γ^＋ cells number, but CD4^＋ IL4^＋ cell number was higher in intranasul immunization groups. The immunization groups using pLXHDmB7.-2 as adjuvant were superior to other groups in immunorespouse. Conclusion These DNA vaccines produce remarkable cellular and humorul immune responses in the mouse and may provide us prophylatic and therapeutic candidates for HPV induced cancer treatment.     

零电压谐振型100kHz开关电源的研制

将软开关技术有效地运用到开关电源中，可以减小开关器件的开关损耗，提高开关电源的工作频率和效率，减小设备的体积和重量。文中阐述了该电路的基本原理和设计零电压谐振型开关电源的几个关键问题，最后给出了实测波形。