弥漫性轴索损伤后CD4~+/CD8~+ T细胞比值、IL-6、IL-10水平变化及预后相关危险因素的Logistic回归分析

目的研究弥漫性轴索损伤(DAI)后患者外周血CD4+/CD8+T细胞比值及炎症因子IL-6、IL-10水平的变化,探讨影响DAI患者预后的相关危险因素及可能的预测因子。方法收集115例DAI患者的相关临床资料及伤后至少6个月的随访结果,并将采集的患者外周血采用流式细胞仪检测CD4+、CD8+T细胞及其比值,ELISA法检测IL-6、IL-10水平,对免疫炎症指标及临床资料进行单因素和多因素分析,多因素分析采用Logistic回归分析。结果DAI后合并其他脑损伤、瞳孔改变、伤后昏迷时间及入院时GCS评分是影响患者预后的危险因素,而其他因素则与预后不相关。CD4+/CD8+T淋巴细胞比值降低是DAI后发生ARDS/ALI的危险因素,CD4+/CD8+T淋巴细胞比值与患者预后关系不大,而ARDS/ALI的发生则是影响DAI患者预后的重要危险因素。IL-6增加与DAI后ARDS/ALI密切相关,可作为ARDS/ALI发生的预测因子,其水平是患者预后的危险因素,而IL-10则在此过程中与ARDS/ALI不相关,且与患者预后无关。结论 CD4+/CD8+T淋巴细胞比值降低是DAI后发生ARDS/ALI的危险因素,IL-6可作为ARDS/ALI发生的预测因子。DAI后与患者预后相关的危险因素包括合并其他脑损伤、瞳孔改变、伤后昏迷时间、入院时GCS评分、IL-6水平及并发ARDS/ALI。     

喷雾干燥法制备LiFePO_4正极材料的最佳工艺参数

以合成的Fe PO4·2H2O为铁源和磷源,Li OH·H2O为锂源,柠檬酸﹑草酸为还原剂,采用喷雾干燥法制备球形Li Fe PO4正极材料.研究喷嘴内径﹑固含量﹑溶解时间﹑进风温度﹑蠕动泵转速对Li Fe PO4形貌的影响.X射线衍射(XRD)和扫描电镜(SEM)分析表明:在喷嘴内径为=0.5 mm,固含量为5%,完全溶解,进风温度160℃,蠕动泵转速750 m L/h时喷雾干燥法合成的Li Fe PO4晶型完整,颗粒均匀.     

半潜式航行器运动特性研究

论文研究了半潜式航行器的运动特性,建立了半潜式航行器的运动学模型,并从深度控制和回转航行两个方面对半潜式航行器的运动特性进行半实物仿真。半实物仿真结果表明：前水平舵是影响深度控制的主要因素,并得出前水平舵舵角和深度的对应关系;回转航行研究了航行器的垂直舵角、航速和回转半径的关系,得出了在一定航速下,不同垂直舵角下的回转半径。此研究准确把握了半潜式航行器的运动规律,为半潜式航行器的设计以及精确控制提供了理论基础。     

地铁列车逻辑控制电路安全服役技术应用研究

为克服传统地铁列车继电器控制电路高故障率和无记录功能等诸多缺陷,提出了基于新型二乘二取二技术的无触点逻辑控制方案.完成了系统架构设计包括热备冗余、网络通信、故障诊断、日志分析等功能.针对既有地铁列车进行了控制电路技术方案设计和施工改造,首先在分析原有控制回路原理的基础上,完成无触点逻辑控制单元替代继电器点位设计;然后综...     

军运保障中高原和山区对汽车性能的影响及对策

从高原和山区的海拔高度及地理环境等对汽车的动力和制动性的影响入手,分析了高原和山区汽车运输的特点,并根据部队的使用经验和试验结论,提出了改善发动机性能和改进汽车制动系的措施,为高原和山区的车辆装备综合管理及技术保障提供了科学的依据。     

基于数值模拟的钛合金锯齿状切屑研究

切削加工中切屑成形是一种典型的大变形问题,它涉及到材料非线性、几何非线性以及边界非线性等问题。本文利用DEFORM-2D对钛合金(Ti6Al4V)进行了锯齿状切屑形成过程的有限元模拟,分析了切削过程中的应力场、应变场及温度场,探讨了锯齿状切屑的形成机理,获得了切削参数对锯齿状切屑形态的影响规律,为优化切削参数、提高刀具寿命提供了参考。     

Innovative strategies for urban car-sharing systems and a simulator to assess their performance

In this paper, three innovative car-sharing systems for urban areas are proposed, based on fleets of individual intelligent vehicles with three service characteristics: instant access, open-ended reservations and one-way trips. These features provide high flexibility but create an uneven distribution of vehicles among stations. Therefore, relocation of vehicles must be performed. Three different system procedures are proposed: in the first system, relocations are performed by users; in the other two, vehicles relocate automatically, thanks to their automation. In the first two systems, vehicles are accessible only at stations, whereas in the third they are also accessible along roads. In order to provide transport managers with a tool to test systems in different realities, an object-oriented simulator is developed. The simulation provides outputs of system performance, in terms of user waiting times and system efficiency. The proposed systems are simulated for the city of Genoa, in Italy, and a comparative analysis is presented.     

The effect of crowding on public transit user travel behavior in a large-scale public transportation system through modeling daily variations

In this paper, the crowding effect in a transit vehicle is modeled in a time-expanded network that considers the daily variation in passenger flows. The study models the daily variation of in-vehicle crowding in a real large-scale transit system. A transit assignment for this real network is modeled and implemented by constructing a crowding cost function that follows the valuation of crowding and by using the reliable shortest path finding method. The direct application of the crowding model to a real network for the Utah Transit Authority indicates that crowd modeling with multi-user classes could influence public transportation system planning and affect the revenues of transit agencies. Moreover, the addition of the disutility factor, crowding, does not always appear to cause an increase in disutility for transit users.     

Instantaneous communication throughputs of vehicular ad hoc networks

Vehicular ad hoc networks (VANETs) formed by connected vehicles in a traffic stream could be applied to improve safety, mobility, and environmental impacts of a transportation system. In this paper, we present analytical models for the instantaneous communication throughputs of VANETs to measure the efficiency of information propagation under various traffic conditions at a time instant. In particular, we define broadcast and unicast communication throughputs by the wireless channel bandwith multiplied by the average probabilities that one vehicle is a successful receiver and sender in a VAENT, respectively. With a protocol communication model, we derive formulas to determine the probabilities for an equipped vehicle to be a successful broadcast receiver and a successful unicast receiver/sender, and obtain broadcast and unicast throughputs along discrete and continuous traffic streams. We further examine the impacts on communication throughputs of the transmission range and the interference range of dedicated short range communication devices as well as the market penetration rate of equipped vehicles and the percentage of senders. Finally, we investigate the influence of shock waves on communication throughputs.     

液化天然气(LNG)汽车日常检查方法及维护技术综述

天然气是一种优质的替代燃料,具有污染小、安全系数高、运行费用低等优点。天然气已经成为城市公共交通领域应用最为成功和广泛的车辆替代燃料技术,为推动交通运输行业的节能减排做出了显著的贡献。液化天然气汽车,作为天然气汽车的一种类型,与传统汽柴油车相比,液化天然气汽车安装了包括液化天然气气瓶、气管路及各种控制阀门和仪表在内的专用装置,在对液化天然气汽车进行日常检查时需要针对液化天然气汽车的专用装置进行重点检查。本文则针对液化天然气汽车的特点,对液化天然气汽车的正确使用方法、日常检查方法及维护技术要求、以及相关注意事项三个方面进行了解读,为指导液化天然气汽车进行日常检查与定期维护提供了技术参考。