β淀粉样肽1～42单克隆抗体的制备

目的　制备稳定分泌β -淀粉样肽 1～ 4 2 (Aβ1-42 )单克隆抗体的杂交瘤细胞 ,产生高效价抗体。方法　通过基因工程技术 ,将Aβ1-42 基因融合于乙肝核心抗原 (HBcAg)的主要免疫优势区 (MIR) ,制备Aβ和HBcAg的融合蛋白 ,免疫BALB/c小鼠 ,取脾细胞与SP2 / 0细胞融合 ,筛选能稳定分泌Aβ1-42 单克隆抗体的杂交瘤细胞。结果　得到两株能稳定分泌Aβ1-42 单克隆抗体的杂交瘤细胞 ,Aβ1-42 单克隆抗体的Ig亚类为IgG3 。结论　制备得到的Aβ1-42 单克隆抗体特异性强 ,效价高     

洛美沙星葡萄糖注射液的药效学研究

报道了洛美沙星葡萄糖注射液的体内、体外抗菌活性，并与其口服制剂及环丙沙星注射液进行了比较。结果表明：洛美沙星注射液是一种广谱、高效、作用迅速的抗菌药物，对革兰氏阳性茵的MIC为0．31～20mg／L，对革兰氏阴性菌的MIC为0．005～10mg／L。杀菌实验表明：对金葡菌、大肠杆菌、痢疾杆菌、肺炎杆菌及绿脓杆菌为杀菌作用。抗菌效果基本不受PH、接种菌量和血清蛋白结合的影响。体内效果（ED50）优于口服制剂。体内、外抗菌活性近似于环丙沙星。     

FEMUR SHAPE RECOVERY FROM VOLUMETRIC IMAGES USING 3-D DEFORMABLE MODELS

IntroductionThe rupture of the anterior cruciate ligament( ACL) has become the most common knee in-juries.In operation of ACL reconstruction,thesurgeons have to find the optimal attachmentpoints resulting in a low anisometry of the graft,while preventing impingement between the graftand the femoral notch.Markus Fleute andStéphane lavallée[1] proposed a real- time systemfor computer- assisted ACL surgery.A recentadvance in surgery is minimally invasive tech-nique that can avoid the large…     

AN EFFECTIVE HUMAN LEG MODELING METHOD

IntroductionFFD is a widely used technique in the field ofsolid modeling and computer animation.Seder-berg and Parry introduced the conceptof FFD[1] ,and Barr provided the basic deformation methodfor FFD[2 ] .Although there are several versionsof FFD in the related literature[3～ 6 ] ,they havethe same basic idea:1 Constructa lattice space.The space can be of any shape,not restricted toparallel- piped cube[5 ] .2 Embed the object intothe lattice space.In other words,impose a localcoordi…     

AN EFFICIENT FAST ENCODING ALGORITHM FOR VECTOR QUANTIZATION

IntroductionAs an effective technique for data compression,VQ[1,2 ] has been successfully used forvarious ap-plications involving VQ- based encoding and VQ-based recognition in both vocal and image pro-cessing.The k- dimensional,N- level vectorquantizer is defined as a mapping from a k- di-mensional Euclidean space Rkinto a certain finitesubset C={Ci,i=1 ,2 ,… ,N },which is called acodebook and whose elements Ci are called code-words.A distortion measure D( X,Ci) is a non-negative dissi…     

DESIGN OF A NEW INTERPOLATED CONTROLLER FOR STABILIZATION OF A SET OF INTERPOLATED PLANTS

IntroductionDynamics of almost all plants in reality variesaccording to the condition under which the plantis operated.An idea to describe the variation ofplant dynamics is interpolating a number of rep-resentative models defined at representative op-erating points.In Ref. [1 ] ,the plant was as-sumed to described as a linear interpolation ofproper stable coprime factorizations of transferfunctions of two representative models and thestabilization problems have been considered. InRef.[2 ] ,it…     

肺癌患者外周血T细胞亚群及免疫细胞活性的研究

采用 APAAP法和流式细胞仪研究 32例肺癌患者及 30例健康人外周血T细胞亚群及免疫细胞活性 ( NK- A)的变化。结果表明 :肺癌患者外周血 CD+3 、CD+4、CD+4/CD+8及 NK- A与正常人比较呈显著性降低 ( P <0 .0 5 ,P <0 .0 1 ) ;且肺癌伴癌转移者与未转移者上述各项指标亦有显著性差异 ( P <0 .0 5 )。说明肺癌患者存在细胞免疫功能降低 ;伴有癌转移的肺癌患者细胞免疫功能更低。提出积极调节肺癌患者细胞免疫功能 ,增强机体抗肿瘤能力十分重要。     

基于USB和FPGA的数据采集系统设计

文章从系统总体结构、硬件设计和软件设计三个方面阐述基于USB和FPGA的多通道同步数据采集与处理系统的设计方法。系统采用FPGA作为主控芯片,实现了A/D转换芯片的控制、数据在双SRAM中的乒乓缓冲控制以及和USB接口芯片CY7C68013A的通信控制。通过USB驱动程序,动态链接库和LabVIEW实现了上位机中数据的显示,处理与存储。该系统能够满足多通道同步数据采集的要求。     

用SPCE061A实现语音录放功能

SPCE061A不但具有单片机的基本功能,而且在语音识别和处理方面有其独到之处,开发环境简单,应用广泛.文中从硬件和软件两个方面介绍了实现语音录放功能的方法,经过调试,达到预期目标.     

电动四轮转向汽车电子差速问题研究

介绍了四轮转向技术和新兴的纯电子差速技术,讨论了四轮转向汽车差速问题的特殊性;建立了基于阿克曼原理的四轮转向低速差速模型;设计了基于TMS320LF2407A DSP的四轮转向及其转向差速电子控制系统,并进行软件编程初步实验,验证了四轮转向技术和电子差速技术的可行性。