The effect of prostaglandin E1 on recovery of early renal graft functions after transplantation

Objective To investigate the effect of prostaglandin E: (PGE1) on recovery of early renal graft functions after transplantation. Methods One hundred and seven patients after renal transplantation were allocated in the treated group, and treated by conventional treatment with injection of 10 μg prostaglandin E1 additionally twice a day for 14 days. And eighty-eight patients who received conventional treatment alone after renal transplantation at the corresponding period were allocated in the control group. Indexes of the two groups, including incidence of delayed graft function and acute rejection reaction, volume of urine, serum certaintie (SCr), endogenous certainties clearance rate (CCr), the blood flow resistance in graft as well as blood viscosity (BV), and platelet aggregation rate (PAR), were determined. Results The urinary volume and endogenous certainties clearance rate of the treated group were significantly higher, but the level of SCr, incidence of renal function recovery retardation, BV, PAR and blood flow resistance in graft were significantly lower than these of the control group (P<0.05). The difference of incidence of acute rejection reaction between the two groups was insignificant (P>0.05). Conclusion Prostaglandin E1 can improve blood microcirculation and decrease the incidence of renal function recovery retardation. These effects are helpful for recovery of renal function after renal transplantation.     

Construction and identification of recombination expression vector Ksp-Cadherin-Gpx1-Kik1

Objective To construct and identify the Gpx1-Klk1 vector which contains kidney-specific promoter (Ksp-cadherin). Methods Through PCR amplification, the human Gpx1, Klk1, and Ksp-cadherin eDNA were obtained by taking Gpx1 cDNA, Klk1 eDNA, and Ksp-cadherin BAC as templates. After being testified, the PCR products were inserted into the expressive vector pIRES-EGFP step-by-step to produce a recombinant vector Ksp-cadherin-Gpx1-Klk1. This vector was examined by restriction enzyme digestion and sequence analysis. Results The recombinant expressive vector Ksp-cadherin-Gpx1-Klk1 was successfully constructed. Conclusion The construction of the recombinant vector Ksp-cadherin-Gpx1-Kik1 laid foundations for investigations in establishing transgenic animal models, the over-expression of Gpx1 and Kikl in mammal kidney, and gene therapy for ischemia-reperfnsion injury during kidney transplantation.     

无偏灰色预测在列车自动驾驶系统中的应用

列车自动驾驶系统是列车控制系统研究中的一部分,可以按照目标速度自动完成运输任务,并且最大程度地节约能源、提高旅行速度。无偏GM（1,1）模型克服传统灰色预测模型存在灰色偏差与抗干扰能力弱的局限性,提高速度预测值的精度。通过算例表明,该方法具有可靠的预测结果,能有效地指导列车自动驾驶。     

老港区改造的土地一级开发商业模式研究

在老港区城市化开发改造中,适当的土地一级开发模式能够有效地保证港口企业国有资产的利益最大化.分析沿海港口企业参与老港区土地一级开发的必要性和关键环节,对典型的土地一级开发模式进行比较.建议沿海港口企业应通过设计符合自身情况的土地一级开发模式,积极参与老港区的城市化开发改造.     

基于MARPOL公约的船舶防污染策略浅析

针对MARPOL公约新要求，结合船舶防污染形势，从立法、航运企业、海事机构、港口码头、设备制造商、航海院校等不同角度分析讨论，提出防污染策略和建议。     

灰色GM（1，1）模型预测沉降的局限性分析

考虑现场沉降监测数据的不等时间间隔性及数据的不断更新性,建立了不等时距等维新息GM(1,1)沉降预测模型并研发了相应的预测程序RIID,将其应用于实际工程的沉降预测,验证了预测模型合理性和程序的可行性。分析了实测数据时间间隔和预测步数对GM(1,1)模型预测精度的影响。结果表明:数据时间间隔相差太大,将导致模型失真;GM(1,1)模型只能进行短期预测,若要预测未来较长时间内的沉降,必须有新增数据,这就使得该模型在实际工程中的应用受到限制。     

DJ1型机车充电器的国产化改造

针对DJ1型电力机车原充电器的缺陷,设计了基于UC3854的Boost PFC电路和基于电流控制型PWM控制芯片UC2846的大功率DC/DC变换器的实用电路,并生产了DJ1型电力机车国产化充电器。实验结果证明,该充电器具有较好的负载特性和稳定性。     

纯电动车热管理系统构建研究

现在国内专业领域针对电动车热管理多集中在电池热管理方向,探讨电机、电池、空调系统整合的整车热管理参考文献不多;主要介绍了纯电动汽车电机、电控等散热需求零件的热管系统构建和电池温控系统发展技术综述与技术趋势。希望通过本文的介绍,对后续热管理系统的发展,推动相关热管理零部件产业化发展提供参考(如通断式电子水阀、流量比例调节的电子水阀、高功率水泵、新型材料的冷却管路等);同时也对控制策略、控制阀值、零部件作动方式进行较为详细的介绍,有一定的参考意义。     

提速道岔1DQJ电路混线实例分析及改进

对提速道岔1DQJ电路中存在的问题进行分析，并提出相应的改进建议。     

基于NiosⅡ的数据采集系统设计与实现

介绍主要以EP1C6Q240C8与TLC548为硬件平台的数据采集系统的设计与实现方案,重点阐述了嵌入式系统NiosⅡ系统的构成及配置,以及硬件平台设计与实现。最后测试证明此数据采集系统能够很好地实现8路AD数据采集及与上位机通信,达到较高的精度和较高的稳定性。