α-干扰素对慢性粒细胞白血病来源的树突状细胞的免疫调节作用(Ⅰ)

目的　于慢性粒细胞白血病 (CML)来源的树突状细胞 (DCs)无血清培养基中 ,加入α 干扰素 (IFN α) ,以探讨IFN α对CML DCs表达共刺激分子及分泌IL 10、IL 12P70的影响。方法　在诱导CML DCs的培养基中 ,除加入SCF、GM CSF、TNF α及IL 4外 ,还加入不同浓度IFN α。培养 10～ 14d后 ,流式细胞仪检测细胞免疫表型 ;G显带法显示Ph1染色体 ;噻唑蓝 (MTT)法检测CML DCs刺激正常人外周血淋巴细胞增殖状况 ;ELISA法检测培养上清IL 10及IL 12P70含量。结果　IFN α(30 0U·mL-1)组较无IFN α组 ,CML DCs的CD4 0、CD83、CD86及MHC I类抗原的表达均升高一倍 ;异体混合淋巴细胞反应 (MLR)中OD值增加一倍 ;Ph1染色体阳性比例、IL 10及IL 12P70浓度均减低。结论　IFN α能够部分纠正CML DCs免疫表型及功能缺陷 ,同其解除了CML血清中IL 10对CML DCs分化的抑制有关     

地铁牵引供电框架保护及功能性改造

针对广州地铁1号线不能远程区分框架保护类型和不能远程复归的状况,结合西门子S5系列PLC技术、SINAUT技术、牵引供电技术,对框架保护进行功能性改造,大大减少了框架保护故障的处理时间.改造技术方案主要通过研究数据的传递方式、协议转换、控制逻辑关系,修改组态软件、监控程序、接口程序、PLC程序的方式来实现.     

STCW78/10公约对航海技术专业人才培养的影响及对策

在概述STCW78/10公约对航海技术专业人才培养产生较大影响的基础上,本文介绍了我国履约的准备情况,提出航海技术专业人才培养应从培养模式、培养途径、培养规格、课程体系和教学手段与方法五个方面进行调整和改革的措施,以应对公约修改对航海人才培养的影响.     

焊前预处理对AlSi10MgMn真空压铸件与铝型材MIG焊接气孔的影响

AlSi10MgMn真空压铸铝合金在MIG焊接存在气孔,其连接方式的选择一定程度上受限,通过对Al?Si10MgMn真空压铸铝合金和型材件进行焊前预处理(氧化皮打磨、酒精清洗、预热处理)后进行MIG焊接,分析了该方案对于焊接气孔的改善效果,结果发现焊前预处理对AlSi10MgMn真空压铸铝合金和型材件MIG焊接气孔改善效果明显,焊缝接头剖面平均气孔率由1.14%降低为0.73%,同时发现焊缝接头剖面中心区域显微硬度值最高,接头强度为180 MPa,接头效率为75%,焊前预处理对显微硬度和接头强度基本无影响。     

我国汽车产业循环经济模式的研究

在借鉴和总结国内外汽车产业在生态设计、减量化制造、废旧汽车回收再利用等方面的先进经验基础上,提出了汽车产业实施循环经济的"4R"原则,按产品生命周期的不同阶段分别探讨了实施循环经济的有效途径,并结合我国的实际特点,提出了相关的政策建议。     

密实型超薄沥青混合料的试验研究

选用SMA-10级配中值、中、上限均值和SAC-10中值3条级配曲线,研究了超薄沥青混合料的路用性能和使用性能.以空隙率4%为设计目标,建立了2.36 mm通过率与最佳沥青用量、宏观构造深度及摩擦系数之间的关系,并对3种级配的超薄沥青混合料做了简要的性能分析和经济评价,研究结论对超薄沥青混合料的设计具有参考价值.     

浅谈新沂10kV配电所微机保护改造施工

东陇海徐州至连云港电化改造时,我们利用此契机对东陇海新沂、邳州、东海10kV配电所及云台山35kV变配电所进行了改造,根据路局要求,改造时全所退出改造,但必须保证贯通、自闭线以及站馈线正常供电.以新沂配电室为例,叙述了如何进行10kV配电所微机保护改造施工.     

Spatial econometric analysis of automobile and motorcycle traffic on Indonesian national roads and its socio-economic determinants: Is it local or beyond city boundaries?

The purpose of this paper is to verify the justification provided for a centralized national road policyin Indonesia, namely, that trips on national roads are typically inter-urban, by measuring the spatialdimensions of automobile and motorcycle trips on national roads in Indonesia. The study finds thatmotorcycle trips are characteristically local; by contrast, automobile trips extend beyond city boundaries,although to a limited extent. The results suggest the decentralization of transportation policies for thedevelopment and maintenance of national roads by granting autonomy to local governments when nofiscal externality exists. The results also indicate that road capacity, gasoline prices, income, populationand worker density, city size, and the number of public buses are strong predictors of vehicle kilometerstraveled.     

Consistency in preferences for road safety: An analysis of precautionary and stated behavior

This study analyzes stated willingness to pay (WTP) for traffic safety, the use of traffic safety equipments, and the consistency between the two. Using data from a Swedish contingent valuation study we find that the estimated value of a statistical life (VSL) based on the respondents' rear-seatbelt usage is similar to the estimate found using the respondents' stated WTP. However, when estimating VSL based on the respondents' use of bicycle helmets we find a significantly higher VSL; the VSL from bicycle-helmet usage is 7 times higher than the estimate based on seatbelt usage. Moreover, we do not find any strong relationship between risk perception and usage, or individual stated WTP and usage. Hence, the main conclusion, based on our analysis, is that stated and observed WTP are not consistent.