60-12号道岔直股开通铺设方案

主要介绍在预留车站内,铺设无砟60-12号道岔(道岔图号:SYC0501A)先开通直股,预留侧股的2种方案,对2种方案的优缺点进行了比较,并介绍了2种方案的铺设流程以及道岔直股开通铺设重点及难点。     

参芪注射液对小鼠60Co射线放疗的增效和减毒作用

目的研究参芪注射液(SQI)对小鼠60 Co射线放疗的增效和减毒作用。方法建立小鼠体内移植性肝癌模型。放疗组小鼠经60 Co射线照射,联合组在照射基础上分别腹腔注射不同剂量的SQI,连续给药7d。计算各组的抑瘤率;测定白细胞计数、脏器指数、血清丙二醛(malonyl dialdehyde,MDA)含量及超氧化物歧化酶(superoxide dismutase,SOD)活性。结果 3个剂量组SQI与60 Co射线合用可发挥协同作用;各剂量SQI联合组均可提高小鼠白细胞计数及脾脏指数(P<0.01和P<0.05),同时对60 Co照射后引起的MDA含量升高和SOD活性降低有一定的逆转作用,且不存在剂量依赖性,而胸腺指数各组之间无差异。结论 SQI对小鼠60 Co射线放疗具有增效和减毒作用。     

基于MS-Fortran Powerstation V4.0的有限元分析系统BNAP

介绍新一代Fortran语言编译器 (MS FortranPowerstationV4 0 )的主要特点及其进行有限元分析系统开发的相关步骤 ,最后给出具体的应用示例 .     

KF60H型自翻车新型倾翻机构设计

针对KF60H侧门全开角度较晚,倾卸性能不佳,甚至出现整车倾翻事故的现象,设计出一种新型倾翻机构。通过对新机构基本原理阐述、动作可行性分析以及倾翻系数的计算,得出该机构是较为优良且可行的机构型式。     

汽车气压制动系反应时间测量系统的实现

反应时间是衡量制动系统一眭能的关键参数之一。文中针对汽车气压制动系,利用MC9S08AW60微处理器和虚拟仪器设计软件LabVIEW实现了一种新型反应时间测量系统。实际应用表明,该测量系统自动化程度高。操作简单,响应速度快。     

外倾式部分斜拉桥重庆嘉悦大桥锚固结构试验及受力分析

介绍了重庆嘉悦大桥的主梁结构特点,以及该桥的主梁节段空间应力仿真分析结果,并介绍了为验证计算结果所做的主梁一节段1∶3缩尺模型试验的研究情况。从理论和实践上探讨了PC主梁部分斜拉桥采用特殊索梁锚固结构的可行性,以及锚固结构在超大索力作用下的安全性,得到了一些对设计、施工有益的结论和建议。     

机车DC600V电源负载试验台微机测控系统设计

机车DC600 V电源负载试验台是保证机车直供电系统正常工作的试验设备,文章根据试验台的具体要求,分别设计了采用PLC的负载控制系统和采用工控机的试验数据测量系统。给出了测控系统的硬件电路和测控软件框图。该系统实现了负载的自动调节和电压、电流、纹波等参数的自动检测,实现了试验数据的自动处理和报表的自动生成。     

DS6-60型计算机联锁系统的研究

DS6-60系统是满足"故障-安全"、采用二乘二取二冗余结构设计的计算机联锁系统。介绍DS6-60型计算机联锁系统的基本架构,详细阐述系统的主要设计原理。     

EFFECTS OF ANTISENSE OLIGODEOXYNUCLEOTIDES ON EXPRESSION OF CASPASE-3 IN Γ-RADIATION INDUCED APOPTOTIC HL-60 CELLS

Objective To study the inhibitory effects of caspase-3 mRNA antisense oligodeoxynucleotides (ASODN) on expressions of caspase-3 and it's mRNA in γ-radiation induced apoptotic HL-60 cells, and screen the effective ASODN. Methods ASODN-1 and ASODN-2 targeting 5′-noncoding region and initial translation region of caspase-3 mRNA were respectively designed, synthesized and introduced into HL-60 cells by means of liposome-mediated transfection followed by 10Gy γ-radiation exposures. TUNEL assay was conducted to investigate the morphologic change and apoptotic percentage of HL-60 cells 18 h later. Immunocytochemical staining and one step RT-PCR were respectively performed to detect the expressions of caspase-3 and it's mRNA. Mismatched oligodeoxynucleotide (MODN) transfected and un-transfected HL-60 cells were taken as control. Results TUNEL assay found that the apoptotic percentages in ASODN-1 and ASODN-2 groups were significantly reduced compared with the control groups (P<0.01) when the final concentration of both ASODNs was ≥3μmol/L. Immunocytochemistry showed that caspase-3 positive cell percentages were reduced but the average gray values increased significantly compared with the control groups (P<0.01). RT-PCR showed expressions of caspase-3 mRNA was decreased after ASODN transfection. Furthermore, ASODN-1 proved more effective in inhibiting HL-60 cell apoptosis than ASODN-2 (P<0.01). Conclusion Caspase-3 mRNA ASODNs can prevent HL-60 cells from apoptosis induced by γ-radiation and reduce expression of caspase-3 and its mRNA. These effects are dose dependent in a certain range.     

840D货车车轮CL60钢在300℃下的低周疲劳特性

以货车车轮CL60钢为研究对象,进行了300℃下的高温低周疲劳实验．研究发现：在循环初期,试样承受的拉压应力幅基本对称;循环末期,拉应力急剧降低,试样产生了失稳断裂;终了时的循环应力。应变曲线反映出了典型的瞬断特征．因此,有必要从断口处进一步研究其微观断裂机理．