A carbon footprint-based closed-loop supply chain model under uncertainty with risk analysis: A case study

The management of products’ end-of-life and the recovery of used products has gained significant importance in recent years. In this paper, we address the carbon footprint-based problem that arises in a closed-loop supply chain where returned products are collected from customers. These returned products can either be disposed of or be remanufactured to be resold as new ones. Given this environment, an optimization model for a closed-loop supply chain (CLSC) in which carbon emission is expressed in terms of environmental constraints, i.e., carbon emission constraints, is developed. These constraints aim to limit the carbon emission per unit of product supplied with different transportation modes. Here, we design a closed-loop network where capacity limits, single-item management and uncertainty on product demands and returns are considered. First, fuzzy mathematical programming is introduced for uncertain modeling. Then, the statistical approach to the possibility to synthesize fuzzy information is utilized. Therefore, using a defined possibilistic mean and variance, we transform the proposed fuzzy mathematical model into a crisp form to facilitate efficient computation and analysis. Finally, the risk caused by violating the estimated resource constraints is analyzed so that decision makers (DMs) can trade off between the expected cost savings and the expected risk. We utilize data from a company located in Iran.     

主动铰接盾构在连续小半径曲线中风化泥岩的掘进控制技术

武汉市轨道交通11号线东段工程光谷四路站—光谷五路站区间为"S"型连续曲线,最小平曲线半径为350 m,采用盾构法施工。通过对主动铰接盾构机掘进控制的难点分析,从土压力、千斤顶推力、千斤顶行程差、水平铰接角度和前盾水平趋向等方面采取有针对性的技术控制措施,使成型隧道轴线、管片错台控制在规范允许范围之内,成功解决了连续小半径曲线隧道盾构施工轴线难以控制、管片容易错台等大问题。     

中国TBM施工技术进展、挑战及对策

总结我国近30年来TBM设计与施工技术的发展历程,可归纳为以下5个阶段:1)研发探索和试用阶段;2)以国外施工承包商为主体,采用国外设计制造TBM施工我国隧道工程阶段;3)独立进行TBM招标采购和选型设计,并建立起自主的TBM施工队伍阶段;4)与国外厂家联合设计制造TBM,工程应用和自主施工快速发展阶段;5)实现TBM国产化,面向国内外TBM工程市场自主施工阶段。通过我国不同时期TBM施工的典型工程,介绍我国在复杂地质、大坡度、高海拔、不同直径、不同机型、超长隧洞TBM施工方面取得的经验、技术积累和业绩,展示我国TBM在穿越断层破碎带、软弱变形、岩爆、涌水等不良地质洞段取得的一系列施工新技术,以及最高月进尺1 868 m、平均月进尺超过600 m和掘进作业利用率超过40%的掘进技术水平。分析TBM在极硬岩、大断层破碎带、软弱大变形围岩、强岩爆围岩、涌水突泥洞段、高地热隧洞和超长隧洞工程中施工面临的风险和挑战,并提出一些相应的技术措施和对策,期望这些措施和对策在未来大量实际工程中进一步得到实践验证、优化和改进,不断积累和创新TBM设计与施工新技术。     

汕头苏埃隧道方案设计关键技术研究

根据汕头苏埃隧道的建设条件,对工程方案设计中的几个技术难点进行研究,并提出解决方案。通过采用"多级分流"理念,实现隧道与北岸4条城市主干道的交通衔接;选择"抛石+排水板"方案解决海域深厚淤泥地层中的围堰设计;8度高烈度震区选择合理的抗震减震措施解决隧道结构抗震;采取双道密封垫和加大密封垫断面的防水设计,满足地震时管片接缝张开量大的防水要求;针对复杂地层,对盾构选型和配置提出建议;对海底凸起进入隧道内的硬岩进行爆破预处理,以降低盾构施工风险。     

拱架式预切槽施工机械在黄土隧道施工中的应用

隧道预切槽施工技术在国外应用比较广泛,但在我国应用还较少。针对黄土地质专项研制了国内首台拱架式预切槽机,并在黄土隧道进行了施工试验。通过施工试验,掌握设备定位、分区切灌、设备行走、施工作业组织等关键技术,并提出应用改进及优化措施。试验结果表明切槽系统工作状态和设备切削、喷灌功能满足设计及施工试验要求,为预切槽同步切削喷灌一体化研究提供了数据支撑和研究方向。     

对农村金融的差异需求与分层供给行为选择的模型分析——基于机制设计理论的视角

文章基于机制设计理论的思想和框架,建立了农村金融市场上差异需求与分层供给行为选择的相关约束机制模型,分析了相关约束机制变量对农村金融供求行为选择的影响,从而提出了通过进一步改进和完善农村金融市场相关机制变量,促进我国农村金融供求者的匹配性行为选择,改善农村金融市场效率,加强金融对“三农”支持力度的政策建议。     

哈绕城高速公路东北段松花江大桥主桥设计方案研究

该松花江大桥为绕城高速公路东北段跨越松花江的一座特大桥,本文介绍了该桥三个桥型方案,并从结构受力、施工难易程度、耐久性、工程经济等方面进行比选提出推荐方案。     

Study on T lymphocyte subsets and NK cells in patients with Graves＇ disease combined with type 2 diabetes

Objective To investigate changes in T lymphocyte subsets and NK cells in patients with simple Graves' disease (GD)and Graves' disease combined with type 2 diabetes mellitus (GD/T2DM). Methods Fifteen cases of GD/ T2DM were selected from our hospital from November 2001 to November 2004. Before and after therapy thyroid function, thyroglobulin antibody (TGA), thyroid microsomal antibody (TMA) and blood glucose level were measured, and T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and NK cells (CD56) were measured by immunofluorescence double labeling monoclonal antibody and flow cytometry, respectively. At the same time, comparison was made with simple GD (15 cases), T2DM (15 cases) and healthy control (20 cases). Results Before therapy, CD4/CD8, CD4 and NK cells in GD/T2DM were less than normal, and there was no significant difference in comparison with simple GD (P<0.05). In T2DM group, only CD4/CD8 and CD4 were less than those of healthy controls (P<0.05). When thyroid function recovered after 1 to 3 months of methimazole treatment in both GD/T2DM and simple GD groups, various indexes recovered, which were more obvious in simple GD. Conclusion Immune hypofunction of GD may be the key to the immune abnormality of GD/T2DM, which is more significant than that of simple GD or T2DM. The recovery of thyroid function and immune abnormality is not consistent, and the recovery of GD is more significant than that of GD/T2DM.     

2型糖尿病患者一级亲属正常糖代谢人群胰岛素抵抗分析

目的探讨2型糖尿病(T2DM)患者糖耐量正常的一级亲属胰岛β细胞功能及胰岛素抵抗情况,并分析胰岛素抵抗的相关因素。方法选取T2DM患者糖耐量正常的一级亲属63例,根据胰岛素抵抗指数分为胰岛素抵抗组及非抵抗组;选取30例健康体检者作为正常对照组。对所选的93例对象进行血压、血糖、胰岛素、血脂的测定,并计算稳态模型胰岛素抵抗指数(HOMA-IR)及胰岛β细胞功能指数(HOMA-β)。结果①糖尿病患者一级亲属组与对照组相比,胰岛素水平、HOMA-IR、HOMA-β明显升高(P<0.05);②胰岛素抵抗组体质指数、舒张压、甘油三酯、餐后血糖、HOMA-β明显高于胰岛素非抵抗组(P<0.05);③相关分析示胰岛素抵抗与体质指数、舒张压、甘油三酯、餐后胰岛素呈正相关(P<0.01,P<0.05),与空腹血糖、餐后血糖、空腹胰岛素、收缩压、胆固醇无显著相关性(P>0.05)。结论T2DM患者一级亲属存在胰岛β细胞代偿性的高分泌,早期已经出现胰岛素敏感性的下降和胰岛素抵抗。胰岛素抵抗与体重增加、舒张压升高及甘油三酯的升高有关。提示对糖尿病患者一级亲属应严格控制体重、血压及血脂,对减少T2DM具有积极意义。