基于IMC理论的十堰城市营销与品牌提升策略

结合整合营销传播的相关理论,分析了十堰城市形象定位与产品设计,提出了十堰城市营销与品牌提升的构想和实施策略。     

电针联合扶正理气合剂对大鼠肝癌生长及转移的影响及相关机制

目的观察电针联合扶正理气合剂对大鼠肝癌生长及转移的影响并探讨其作用机制。方法雄性Wistar大鼠200只,随机分为5组。以二乙基亚硝胺(DEN)灌胃诱导大鼠肝癌模型,电针组造模同时给予电针足三里、关元、内关、三阴交、肝俞穴治疗,扶正理气合剂组给予扶正理气合剂灌胃,针药联合组则予上述电针和扶正理气合剂治疗,共16周。造模16周后处死大鼠取肝脏组织标本,肉眼及光镜下观察肿瘤生长和转移情况;免疫组化法测定肝组织NF-κB活性及微血管密度(MVD),RT-PCR法检测肝组织中转化生长因子β1(TGF-β1)mRNA及血管内皮生长因子(VEGF)mRNA表达,放射免疫法测定肝组织活性氧(ROS)、抗氧化能力(T-AOC)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)活性、脂质过氧化产物(LPO)含量。结果与正常对照组比较,模型组大鼠的肿瘤生长和转移参数、ROS、LPO含量、NF-κB活性、TGF-β1 mRNA、VEGF mRNA、MVD表达显著增加(P<0.01),而T-AOC、SOD、GSH-Px、CAT活性明显下降(P<0.01);与模型组比较,各治疗组大鼠的肿瘤生长和转移参数、ROS、LPO含量、NF-κB活性、TGF-β1mRNA、VEGF mRNA及MVD表达显著下降,而T-AOC、SOD、GSH-Px、CAT活性明显上升(P<0.01),联合治疗组上述指标优于其他治疗组(P<0.05)。NF-κB活性与TGF-β1mRNA及VEGF mRNA呈正相关关系(r1=0.554,P<0.05;r2=0.572,P<0.05)。结论电针和扶正理气合剂均能显著降低实验性肝癌大鼠的NF-κB活性、TGF-β1mRNA及VEGF mRNA及MVD表达,从而降低肿瘤生长和转移参数,这与其清除自由基有密切关系。     

大型活动中心交通需求管理策略研究

在对大型活动中心交通供需特性分析的基础之上．论证了大型活动中心需要采取交通需求管理的可行性和必要性,并分别从活动中心活动参与者以及过境出行者两个不同群体的角度提出了大型活动中心实施交通需求管理的具体目标和关键问题。并以上海市浦东三林体育中心为研究对象,对处于城市中心区的大型活动中心实施交通需求管理的策略进行了实例分析。     

从营销理念谈欠发达地区高校人才招聘

欠发达地区高校资金、人力资源相对贫乏,要保持可持续发展,其竞争优势来源于高校的核心能力,人力资源是构建高校核心能力的基础。人才招聘是需要进行营销策划,并始终加以贯彻执行的。     

大鼠海马神经元自发放电对皮下注射福尔马林的反应

采用玻璃微电极细胞外记录法，观察了清醒完整大鼠海马神经元自发放电对皮下注射福尔马林的反应。结呆显示，在海马CA2／CA3区可记录到痛兴奋、痛抑制和非痛敏三种神经元。同侧前爪皮下注射福尔马林后，痛兴奋神经元的自发放电显著增多，而痛抑制神经元的自发放电显著减少，这种变化在给予福尔马林后30min左右达到最大值，在60min左右恢复到对照水平；但在给予福尔马林后，非痛敏神经元的自发放电无明显变化。以上实验结果提供了在福尔马林痛模型中，海马在痛感受或痛反应过程中发挥一定作用的电生理证据。     

汽车概念营销策略分析

随着汽车市场竞争的加剧,概念营销开始受到汔车厂商的重视,并得到了广泛的应用。本文对汽车厂商在概念营销过程中所遇到的问题进行了初步的探讨。     

Women’s mode and trip structure choices in daily activity-travel: a developing country perspective

ABSTRACT

In this paper, we analyze the travel patterns of Iranian women, where typical patriarchal views and specific social and cultural norms may differ from the patterns of those in western societies. In addition to inherent psycho-physical gender differences, women in Iran can face special constraints forcing them not to be involved in all activity-travel patterns that people in developed countries usually undertake. We pay special attention to the role of marital and employment status on women’s activity-travel patterns. To this end, we develop a joint mode and daily activity pattern (DAP) discrete choice model, which is a two-level mixed nested Logit. The upper nest of the proposed model embodies women’s DAP choices, and the lower nest belongs to the mode choices. In this paper, we try to show how different factors in a patriarchal Muslim society like Iran affect or restrict women’s type and structure of activity-travel patterns.     

某客运专线新站楼盖天桥人行激励下的振动舒适度计算

采用三维有限元法,对某客运专线新站站房人行天桥进行人行荷载激励作用下的振动时程响应分析,得到该人行天桥的自振特性以及横竖向加速度和位移响应.与已有的国内外规范和传统的桥梁振动舒适度评价标准进行对比分析,对该天桥在随机人行荷载激励作用下的行走舒适度进行评估.     

谈IT企业的品牌策略

从品牌营销的定义入手,通过广告营销、价格营销的对比阐述了品牌营销的特点,并对IT企业内品牌营销特点进行了分析。     

Analysis of telecommuting behavior and impacts on travel demand and the environment

The discussion of whether, and to what extent, telecommuting can curb congestion in urban areas has spanned more than three decades. This study develops an integrated framework to provide the empirical evidence of the potential impacts of home-based telecommuting on travel behavior, network congestion, and air quality. In the first step, we estimate a telecommuting adoption model using a zero-inflated hierarchical ordered probit model to determine the factors associated with workers’ propensity to adopt telecommuting. Second, we implement the estimated model in the POLARIS activity-based framework to simulate the potential changes in workers’ activity-travel patterns and network congestion. Third, the MOVES mobile source emission simulator and Autonomie vehicle energy simulator are used to estimate the potential changes in vehicular emissions and fuel use in the network as a result of this policy. Different policy adoption scenarios are then tested in the proposed integrated platform. We found that compared to the current baseline situation where almost 12% of workers in Chicago region have flexible working time schedule, in the case when 50% of workers have flexible working time, telecommuting can reduce total daily vehicle miles traveled (VMT) and vehicle hours traveled (VHT) up to 0.69% and 2.09%, respectively. Considering the same comparison settings, this policy has the potential to reduce greenhouse gas and particulate matter emissions by up to 0.71% and 1.14%, respectively. In summary, our results endorse the fact that telecommuting policy has the potential to reduce network congestion and vehicular emissions specifically during rush hours.