EZH2基因在宫颈癌中的表达及其意义

目的研究EZH2(enhancer of zeste homolog 2,EZH2)基因在宫颈癌组织中的表达及其意义。方法采用RT-PCR方法检测20例正常宫颈组织和60例宫颈癌组织中EZH2mRNA的表达情况,并结合临床资料分析其与宫颈癌各临床病理特征的相关性。结果 EZH2mRNA在宫颈癌组织中的表达高于正常宫颈组织(0.86±0.17 vs.0.06±0.02,P<0.01),EZH2mRNA表达与患者年龄及肿瘤大小无明显相关性(P>0.05),而与肿瘤细胞分化、临床分期、浸润深度及淋巴结转移密切相关(P<0.05)。结论 EZH2基因表达增强与宫颈癌恶性生长及不良预后有关。     

公路网抗灾应急救援系统的规划建设

近年来自然灾害的频频发生使相关地区的公路网遭受了不同程度的破坏,公路网抗灾应急救援系统的规划建设成为区域抗灾的紧迫任务.回顾了道路交通应急救援的研究现状;从组织体系、工作机制及救援机构的选址3方面探讨了公路网抗灾应急救援系统的规划内容;以杭州市公路网为例,对其公路网抗灾应急救援系统进行规划,实践验证了研究成果的可行性.     

新农村建设背景下农村公路网规划研究

通过对农村公路网基本概念和特点的分析,提出农村公路网规划要紧紧围绕新农村建设的中心任务和总体要求,坚持统筹规划、逐步实施、区别对待、因地制宜、思路清晰、方法实用、安全方便和节约环保等规划原则。探讨了农村公路网规划的基本方法,提出了农村公路网布局规划的基本思路,为新农村建设中农村公路网的规划提供一定的参考意见。     

基于多属性决策运输车编配方案研究

在信息化战争中,后勤运输保障举足轻重。根据部队运输需求,制定出科学合理的运输车编配结构对于提高部队公路运输保障能力具有重要的指导意义。分析了我军运输车编配存在的问题,介绍了基于最大离差化的多属性决策模型,为运输车编配方案评价提供了一种合理的研究方法。并以某摩步师直属汽车营为例,对运输车的备选方案进行了排序和选优,得到了...     

浅析如何提高汽车售后服务质量

文中从汽车售后服务的作用出发,对我国汽车售后服务方面存在的问题进行了简要分析,针对如何提高汽车售后服务质量提出了几点对策。     

负指数函数表征沥青路面单值指标性状分析

采用裂缝率、车辙、横向力系数和功能性破损率四个指标衡量沥青路面是否达到预防性养护标准。结合选取的锦阜、锦朝高速公路代表性路段检测数据分析评价,负指数函数y=a.e-bx能够很好地表征路面单值指标性能变化规律。通过分析预测,得到了锦阜、锦朝高速公路最佳的预防性养护年限。     

黄土路堤沉降特性与工后沉降预测模型分析

阐述了黄土的分布与性质,对黄土路堤沉降的机理及原因进行了分析.分析比较了基于实测资料预测黄土路堤工后沉降值的实用模型,包括指数模型,幂函数模型,双曲线模型.以指数模型为例,根据已建成某大坝实测数据,确定了预测模型的参数.     

Changing accessibility, dwelling price and the spatial distribution of socio-economic activities

In this paper we present an activities-location choice model with endogenous price which simulates, based on Expected Random Utility principle, the behaviour of several agents of the urban system (e.g. the workers distinguished by income, the firms by economic sector) to estimate the spatial distribution of socio-economic activities within the study area as well as the impact of differential changes in accessibility on the dwelling price. The study area for this research is the metropolitan area of Napoli (South Italy), for which we show the results of the model estimation and the results of a “backcasting” analysis.     

Hydroelastic code-to-code comparison for a tension leg spar-type floating wind turbine

The development of robust design tools for offshore wind turbines requires knowledge of both wave and wind load models and response analysis. Verification of the numerical codes is required by the use of experiments and code-to-code comparisons. This paper presents a hydroelastic code-to-code comparison between the HAWC2 and USFOS/vpOne codes for a tension leg spar (TLS) wind turbine with a single tether. This concept is hence based on the TLP and Spar concepts. The comparison is performed using coupled hydroelastic time domain simulations. Several aspects of modelling, such as wave simulation, hydrodynamic and structural modelling, are addressed for the TLS. Wave-induced motions of the support structure affect the power performance of a wind turbine. Furthermore, overload of the tension leg should be avoided. In this paper, the motion and tension responses are compared. The tension leg introduces nonlinear effects on the spar motion. These nonlinear effects include combined-frequency effect such as double, difference and sum of wave, as well as natural pitch and surge frequencies. Hydrodynamic loads are based on a combination of the Morison formula and the pressure integration method. A comparison indicates that the motion and tension responses obtained in the two codes are in good agreement.     

混合语言编程在船舶水动力计算中的应用

针对VC++具有面向对象特征和开发图形界面方面的强大功能以及FORTRAN语言在数值计算方面的优势,着重介绍了VC++和FORTRAN二种语言混合编程需要的技术要点和实现方法.对混合编程规则中的调用约定、命名约定、数据的交换与传递、多维数组的传递、DLL的调用方式以及DLL的调试进行了详细的阐述,并通过两者的混合编程实现了对船舶水动力的计算.该计算精确而便捷,对船舶操纵预报、安全评估等方面的研究有很大的应用价值.