路网效益测算方法初探

针对铁路运输项目的系统性，介绍了利用O－D流计算新建铁路路网效益的方法，解决了在进行新建铁路项目经济评价中间接效益计算粗略的问题，并给出示例。     

南友路膨胀土路堤处治方法

分析总结了国内外膨胀土路堤的主要处治方法 ,针对南友路膨胀土的性质 ,进行了室内掺灰改性试验、模拟封闭条件下路基土的土性试验 ,由此提出了一套以封闭为主的膨胀土路堤处治方法。     

等间隔放样圆曲线的两种新方法

阐述了等间隔放样圆曲线的基本原理，介绍了放样要素采集的基本方法，叙述了弦角弦长法及坐标法放样圆曲线的过程。     

青岛港前湾港区软土地基处理方法及效果分析

采用强夯法处理上部回填土,塑料排水板法固结下部软土的联合施工工艺使软土土体强度得到提高。通过孔隙水压力及地表沉降观测监测软土地基固结过程,并计算固结度确定检测时间,评价最终的地基处理效果;通过分析强夯时孔隙水压力增量与深度关系曲线,确定强夯有效加固深度,反算出有效加固深度修正系数,它可以用于工程地质条件相似地区强夯设计的参考依据。     

小水线面双体船结构优化

本文对小水线面双体船结构优化设计方法进行了研究。以-570t外倾式小水线面双体船为结构优化对象,根据劳氏船级社特种船舶入级规范中的有关要求作为其约束条件,利用混合离散变量优化方法(MDOD法)对该船进行了结构优化设计。     

三角臂与车箱地板之间干涉的简单确定

T式举升机构自卸车在倾卸运动过程中，地板与三角臂之间的极限位置可通过画图的简单方法来确定。介绍了此种画图方法，并通过实践进行了检验。     

宁高新通道工程石臼湖特大桥主桥箱梁合龙段施工技术研究

宁高新通道石臼湖特大桥公路与轻轨并线架设,中间轻轨桥,两边公路桥,主桥位于秦淮河航道上,施工交叉作业多,施工组织难度大。文中对该桥主桥箱梁合龙段施工,由传统吊架施工工艺改变为直接利用挂篮进行合龙施工,并从施工控制,合龙顺序、体系转换、模板安装、混凝土浇筑等一系列工艺进行了详细的叙述,总结出一套完整的主桥箱梁合龙施工工艺,并且在项目中成功应用,最终完成了主桥桥箱梁合龙段施工。     

桥梁施工中桥墩倾斜原因及案例分析

鉴于桥梁施工中容易出现桥墩倾斜的问题,主要分析了桥梁施工中墩柱发生倾斜的原因,简要总结了相应的处理措施。通过实际案例分析了桥梁施工中桥墩倾斜发生、发展的过程,提出相应的加固方案,希望对以后的施工提供有用的借鉴。     

Effect of ABCA1-V771M polymorphism on plasma lipid levels and its relationship with coronary atherosclerotic heart disease

Objective To explore the risk association of ABCA1-V771M polymorphism with coronary heart disease (CHD) in Hart nationality in Northwest of China. Methods With case-control study, ABCA1-V771M polymorphism was detected in 204 unrelated Hart nationality people in Northwest of China, and all the subjects by coronary angiography were grouped into 106 cases and 98 controls. The genotypes and alleles frequency distribution of ABCA1-V771M polymorphisms were analyzed by PCR-RFLP analysis, and the clinical statistics of serum lipids were compared and its effects of ABCA1-V771M polymorphism on the plasma lipid levels and coronary atherosclerotic heart disease were analyzed. Results The genotypic frequencies of ABCA1-V771M polymorphism matched well under Hardy-Weinberg equilibrium (P>0.05), V and M allelic frequencies were 33.3% and 66.7%. In comparison with VV VM genotype carriers, MM genotypes carriers had much lower plasma levels of HDL-C (P<0. 001) and much higher plasma levels of TG (P<0. 05). M allelic frequency in CHD group was significantly higher than V allelic frequency (P<0. 05). M allele was related with more severity of atherosclerosis in the coronary artery than V allele (P<0.05). However, there was no obvious difference in the incidence of AMI among carriers with three genotypes of ABCA1-V771M polymorphism (P>0.05). Conclusion ABCA1-V771M polymorphism was not only associated with the plasma levels of HDL-C and TG, but also related to the susceptibility and severity of coronary atheroselerotic heart disease. Moreover, M771 allele appeared to be atherogenie among Han population in Northwest of China.