IP_3R1在弥漫性轴索损伤后早期的表达及其意义

目的通过观察大鼠弥漫性轴索损伤(diffuse axonal injury,DAI)后I型1,4,5-三磷酸肌醇受体(inositol 1,4,5-trisphosphate receptor type I,IP3R1)表达随时间的变化,探讨其作用,为DAI后轴索的继发性损伤及断裂提供研究基础。方法 25只健康雄性成年SD大鼠,随机分为对照组和实验组(DAI组),采用Golgi镀银染色及SP免疫组织化学染色,观察其在不同时间(3~72h)的脑干组织病理变化及IP3R1的表达情况。结果 Golgi镀银染色证明大鼠DAI模型成功;免疫组织化学染色显示,对照组大鼠脑干中IP3R1有弱阳性表达,实验组阳性细胞较对照组明显增高,在DAI损伤后,大鼠脑干组织IP3R1表达3h时就开始升高,至24h高峰后开始下降,72h下降至低水平。结论IP3R1可能在DAI后轴索的继发性损伤及断裂中起重要作用。     

基于40Cr杆件的防腐涂层腐蚀试验研究

在保证抗拉强度的情况下,为降低40Cr杆件表面腐蚀并提高其表面硬度,本文设计了镍铬合金/金属陶瓷复合涂层及镍铬合金/含防污剂的微纳米Al2O3.TiO2复合涂层,并对WCCoCr、CrCCrNi、Al2O3.TiO2及氧化铬等陶瓷涂层进行了中性盐雾腐蚀、电偶腐蚀、实海腐蚀等试验,试验结果表明高速火焰+爆炸喷涂微纳米Al2O3.TiO2复合涂层综合性能良好,可有效提高杆件的耐腐蚀性能和表面硬度。     

深水起重铺管船A&R绞车系统设计研究

基于对深水起重铺管船作业系统设备的设计及应用研究,重点阐述AR绞车的系统组成、结构特点、设计选型及控制系统原理。通过详细分析系统中的牵引绞车、储缆绞车、导向滑轮、补偿装置及PLC控制系统,提出一整套设计思路与方法,解决工程师在系统设计中遇到的诸多问题。     

Can we reduce car use and, if so, how? A review of available evidence

Transport accounts for nearly a quarter of current energy-related carbon dioxide emissions with car travel constituting more than three quarters of all vehicle kilometres travelled. Interventions to change transport behaviour, and especially to reduce car use, could reduce CO₂ emissions from road transport more quickly than technological measures. It is unclear, however, which interventions are effective in reducing car use and what the likely impact of these interventions would be on CO₂ emissions. A two-stage systematic search was conducted focusing on reviews published since 2000 and primary intervention evaluations referenced therein. Sixty-nine reviews were considered and 47 primary evaluations found. These reported 77 intervention evaluations, including measures of car-use reduction. Evaluations of interventions varied widely in the methods they employed and the outcomes measures they reported. It was not possible to synthesise the findings using meta-analysis. Overall, the evidence base was found to be weak. Only 12 of the 77 evaluations were judged to be methodologically strong, and only half of these found that the intervention being evaluated reduced car use. A number of intervention approaches were identified as potentially effective but, given the small number of methodologically strong studies, it is difficult to draw robust conclusions from current evidence. More methodologically sound research is needed in this area.     

插值滤波器在单站外辐射源无源定位中的应用

把一种基于stirling内插公式的插值滤波器（DDF），应用于单站外辐射源无源定位中的非线性滤波问题。与传统扩展kalman滤波（EKF）相比，插值滤波器避免了非线性方程泰勒展开求解的过程，同时实现复杂性和计算量都很小。计算机仿真表明，一阶插值滤波（DD1）滤波精度相当EKF，而二阶插值滤波（DD2）滤波精度接近甚至略优于无轨迹kalman滤波（UKF）。     

基于目标和模式的软件体系结构设计

为了处理动态需求和实现需求到设计的映射,本文提出基于目标和模式的体系结构设计过程,实现了需求到设计的过渡,并提出目标层次和元素层次,实现了需求的可跟踪。最后针对缺陷和测试用例管理等方面的计算机辅助工具的设计给出了基于J2EE模式的体系结构设计的一个实例。     

纳米TiO_2光催化空气净化技术研究进展

本文对纳米TiO2光催化净化空气中挥发性有机化合物(VOCs)的技术原理、国内外研究现状和进展进行概述,简介部分使用光催化空气净化技术的商业产品,展望该技术的应用前景。     

京郑既有线CTCS2级信号系统方案研究

分析了京郑线信号系统既有低频信息的特殊性,提出了在京郑线提速200km/h,车载设备能够兼容其他提速200km/h线路的CTCS2解决方案,工程可实施性强。     

Evaluating transfer velocity-wind speed relationship using a long-term series of direct eddy correlation CO2 flux measurements

Long-term observations of the marine atmospheric boundary layer were performed by an eddy correlation system, which was set-up on a platform in the Baltic Sea. In this experiment the three-dimensional wind vector and the turbulent fluxes of momentum, sensible and latent heat and CO₂ were measured for one and a half years. Simultaneously the CO₂ partial pressure p_CO2 in surface water was measured by a submersible autonomous moored instrument for CO₂ at the platform in 7-m depth. The high-resolution eddy correlation measurements of the atmospheric CO₂ flux F_CO2, together with the measurements of the CO₂ partial pressure differences between air and sea Δp_CO2 led to a long-term data set which provided the possibility to investigate the parameterization of the CO₂ transfer velocity k as a function of 10-m wind speed u in a statistical manner. From half-hour mean CO₂ fluxes and CO₂ partial pressure differences, k was calculated using k = F_CO2 / (K₀Δp_CO2), with K₀ the CO₂ solubility. The half-hour mean data points, used for the determination of the k–u parameterization, show large scatter. However, assuming a linear, quadratic dependency the analysis yields: k₆₆₀ = 0.365u² + 0.46u (k at 20 °C and salinity 35 psu) with a correlation coefficient of r² = 0.81. The large scatter indicates that the kinetics of the air–sea CO₂ transfer velocity is not only a function of the wind speed alone, but might also be controlled by other environmental parameters and mechanisms, such as sea state and surface coverage with surfactants.     

推进GSM-R网络建设适应铁路跨越式发展

分析了国内外铁路GSM—R系统应用的发展，以及我国铁路工程建设跨越式发展对GSMR系统的迫切需要，阐明加快推进我国铁路GSM—R系统建设的必要性。针对我国铁路GSMR网络建设需要先期开展的核心网建设和互联互通测试等工作提出实施方案建议。