排序方式: 共有67条查询结果,搜索用时 15 毫秒
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目的探讨白细胞介素13(IL-13)在几种常见病理类型的原发性肾小球肾炎(PGN)患者肾组织中的表达及其意义。方法采用免疫组织化学法检测81例PGN患者及10例对照组肾组织中IL-13的表达情况,并与各项临床指标进行相关性分析。结果PGN患者肾组织中IL-13表达均较对照组明显增强;IL-13在PGN患者肾组织中的表达与血尿素氮、肌酐水平、24h尿蛋白定量以及肾小球新月体形成呈正相关(r分别为0.325,0.275,0.291,0.231),而与肾小球滤过率(GFR)、血清白蛋白水平呈负相关(r分别为-0.448,-0.296)。结论IL-13参与PGN患者肾组织的炎症反应及肾小球新月体的形成过程,并与肾功能进展及尿蛋白严重程度密切相关。 相似文献
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2002年11月的“威望”号轮事故的发生促使国际海事组织(IMO)第50届特别海上环境保护委员会通过了对《73/78防污公约》附则Ⅰ的修正案,修订了淘汰单壳油船的时间表(第13G条),并增加了限制单壳油船载运重油的新规定(第13H条)。于2005年4月5日生效的该修正案对全球油船运输业产生了重大的影响。 相似文献
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Albert Lutz Bernhard Schick Henning Holzmann Michael Kochem Harald Meyer-Tuve Olav Lange 《Vehicle System Dynamics: International Journal of Vehicle Mechanics and Mobility》2017,55(10):1432-1497
ABSTRACTVehicle simulation has a long tradition in the automotive industry as a powerful supplement to physical vehicle testing. In the field of Electronic Stability Control (ESC) system, the simulation process has been well established to support the ESC development and application by suppliers and Original Equipment Manufacturers (OEMs). The latest regulation of the United Nations Economic Commission for Europe UN/ECE-R 13 allows also for simulation-based homologation. This extends the usage of simulation from ESC development to homologation. This paper gives an overview of simulation methods, as well as processes and tools used for the homologation of ESC in vehicle variants. The paper first describes the generic homologation process according to the European Regulation (UN/ECE-R 13H, UN/ECE-R 13/11) and U.S. Federal Motor Vehicle Safety Standard (FMVSS 126). Subsequently the ESC system is explained as well as the generic application and release process at the supplier and OEM side. Coming up with the simulation methods, the ESC development and application process needs to be adapted for the virtual vehicles. The simulation environment, consisting of vehicle model, ESC model and simulation platform, is explained in detail with some exemplary use-cases. In the final section, examples of simulation-based ESC homologation in vehicle variants are shown for passenger cars, light trucks, heavy trucks and trailers. This paper is targeted to give a state-of-the-art account of the simulation methods supporting the homologation of ESC systems in vehicle variants. However, the described approach and the lessons learned can be used as reference in future for an extended usage of simulation-supported releases of the ESC system up to the development and release of driver assistance systems.Abbreviations: ABS: Anti-lock braking system; ADR: Australian design rules; ALB: Automatic load-dependent brake force controller; AMEVSC: Alternative method to assess the electronic vehicle stability control system; APP: Application; BSC: Brake slip controller; CAE: Computer-aided engineering; CAN: Controller area network; CAT: Category; CoG: Centre of gravity; DIN: Deutsches Institut für Normung (German Institute for Standards); EB+: Trademark of Haldex; EBD: Electronic brake force distribution; EBS: Electronic brake system; ECU: Electronic control unit; ESC: Electronic stability control; ECVWTA: European Community Whole Vehicle Type Approval; FMVSS: Federal motor vehicle safety standards; GPS: Global positioning system; GRRF: Groupe de travail en matiere de roulement et de freinage (Working Party on Braking and Running Gear); HiL: Hardware-in-the-Loop; HSRI: Highway Safety Research Institute; K&C: Kinematic and compliant (KnC); MBS: Multibody systems; MPV: Multipurpose vehicle; NHTSA: National Highway Traffic Safety Administration; OEM: Original equipment manufacturer; SiL: Software-in-the-Loop; ST: Summer tyres; STM: Single track model; StVO: Straßenverkehrsordnung (Government Highway Regulations); SUV: Sports utility vehicle; SW: Software; SwD: Sine with dwell manoeuvre; TC: Threshold consumption value; TCS: Traction control system; TRIAS: Test Requirements and Instructions for Automobile Standards; UN/ECE: United Nations Economic Commission for Europe; VAF: Value-added function; VDC: Vehicle dynamics controller; VTC: Vehicle test catalogue; WT: Winter tyres 相似文献
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AR-AC13橡胶沥青混合料设计与施工 总被引:1,自引:0,他引:1
AR-ACl3橡胶沥青混合料在江苏省大规模应用尚属首次,结合相关科研成果,在室内目标配合比及生产配比设计试验的基础上,通过宁常(南京-常州)高速公路的大规模铺筑确定了混合料合理的施工工艺,为橡胶沥青混合料路面的推广应用积蕾了经验. 相似文献
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针对AK-13B抗水损害能力较差的缺点,在某城市旧路加铺改造的实际应用中,对AK-13B从配合比设计到施工均作了一定的调整和改进,取得了优良的路用性能。此经验可为同类工程提供借鉴。 相似文献
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