Insulin-3基因敲除鼠生殖系统LGR8蛋白的表达

目的 Insulin-3(Insl3)和其唯一配体富含亮氨酸的G蛋白受体[LGR8(aka RXFP2)]系统在睾丸下降过程中起重要作用。本研究拟利用Insl3基因敲除鼠探讨Insl3与LGR8相互关系及其在生殖系统的表达情况。方法使用免疫共沉淀、Western blot及免疫组化法检测雄性野生型小鼠和Insl3基因敲除雄性小鼠各生殖器官LGR8蛋白的表达并比较分析。结果 LGR8蛋白在野生型小鼠睾丸、睾丸引带、附睾及输精管等多个雄性生殖器官均有表达。其表达程度在不同生殖器官不同,野生型小鼠睾丸LGR8的表达强于Insl3基因敲除鼠(P<0.05)。结论 LGR8蛋白在多个雄性生殖器官均有表达,Insl3-LGR8系统可能在男性多种生殖发育疾病中起作用。     

G108线（太原段）勘察设计中地质灾害的应对

近年来自然灾害对公路运营的影响趋于频繁,究其原因既有客观因素,也有主观因素。公路勘察不细、设计周期不足、施工方案不当等都是造成公路地质灾害的主要因素。在公路勘察、设计时,应针对地质灾害采取合理措施进行应对。     

运用灰色理论与人工神经网络预测公路沉降

介绍了灰色理论中的G（1,1）模型、BP人工神经网络模型和灰色BP神经网络模型;根据岳阳城陵矶进港道路管桩处理后的路基沉降实测资料,分别运用这三种模型进行沉降预测,并对预测结果进行了分析,比较了这三种方法预测沉降的效果。     

Efficient peer-to-peer file sharing in 3G networks

In 3G networks upgraded with high speed packet access (HSPA) technology, the high access bandwidth and advanced mobile devices make it applicable to share large files among mobile users by peer-to-peer applications. To receive files as quickly as possible is essential for mobile users in file sharing applications, since they are subject to unstable signal strength and battery failures. While many researches present peer-to-peer file sharing architectures in mobile environments, few works focus on decreasing the time spent in disseminating files among users. In this paper, we present an efficient peer-to-peer file sharing design for HSPA networks called efficient file sharing (EFS) for 3G networks. EFS can decrease the dissemination time by efficiently utilizing the upstream-bandwidth of mobile nodes. It uses an adaptive rearrangement of a node’s concurrent uploading transfers, which causes the count of the node’s concurrent uploading transfers to lower while ensuring that the node’s upstream-bandwidth can be efficiently utilized. Our simulations show that, EFS achieves much less dissemination time than other protocols including Bullet Prime and a direct implementation of BitTorrent for mobile environments.     

基于EASY5的船舶舵机电液伺服系统建模与仿真

电液伺服系统在船舶液压控制中有着极其重要的地位。采用目前先进的MSC EASY5软件对某船舶舵机电液伺服系统进行建模并仿真,仿真结果与实际运行情况基本吻合,这对分析舵机液压系统的静、动态特性,优化系统有着重要的意义。     

A Multi-homed VPN Architecture Based on Extended SOCKS＋TLS Protocols

IntroductionThe security and performance of corporatenetwork system (end system) is becoming increas-ingly important, so VPN systems are often de-ployed to enhance the security of end systems.AVPN is provisioned over public or a third networkinfrastructure through different security protocols,to provide dedicated connectivity to a closed groupof users. The current tunneled VPNs are morelightweight but without over-provisioning by thenetwork provider give no assured quality of serviceand th…     

五楞冲击压路机冲击破碎旧水泥路面板的力学效果分析

该文针对冲击碾压破碎技术在旧水泥混凝土路面修复中的应用,采用三维有限元方法研究了五楞冲击压路机冲击破碎施工时旧路面结构及土基的受力、变形特征。分析了冲击压实荷载位于路面板不同位置对板体破裂、基层受力及土基受压效果的影响,探讨了冲击压实荷载在板下路基中的传递规律及作用深度等问题。研究成果可为冲击压实改建旧混凝土路面施工技术提供理论参考和指导。     

5U北美岩沥青改性沥青路用性能试验研究

5U北美岩沥青是一种天然沥青改性剂,为评价其路用性能,采用流变学方法对5U北美岩沥青改性沥青胶浆性能进行了动态温度扫描,对改性后沥青混合料的高温性能与抗水损坏性能进行了室内评价。研究结果表明:经5U北美岩沥青改性后的沥青胶浆车辙因子明显提高,弹性增加;沥青混合料抗车辙能力和抗水损害能力明显改善。     

基于公共网络的高速铁路无线远动调试技术研究

鉴于新建铁路电力牵引供电系统的远动系统调试与有线光纤通道敷设的缓慢滞后存在矛盾,提出一种新型铁路电力无线远动通道和无线远动后台调试系统,分析了现有通信技术,并结合接入模式设计无线传输方案;通过3个阶段的方案具体实施,并将测试结果与指标进行比较,验证了方案的可行性.该通道可根据站点的数量进行扩展,亦可作为应急远动通道使用...     

Impact of climate change on pavement structural performance in the United States

This study uses climate projections from multiple models and for different climate regions to investigate how climate change may impact the transportation infrastructure in the United States. Climate data from both an ensemble of 19 different climate models at both RCP8.5 and RCP4.5 as well as three individual prediction models at the same Representative Concentration Pathways (RCP) levels is used. These models are integrated into the AASHTOWare Pavement ME software to predict the pavement performance. Comparisons are made between the predicted performance with respect to typical pavement distresses using both historical climate data as well as climate projection data. Though there is substantial variation for different prediction models in terms of the magnitude of the impact, the consistency in results suggest that projected climate changes are highly likely to result in greater distresses and/or earlier failure of the pavement. This finding is consistent across all the climate zones studied, but varies in magnitude of 2–9% for fatigue cracking and 9–40% for AC rutting at the end of 20 years depending on the climate region of the pavement section and prediction model used. This study also compares the impacts incorporating temperature only projections with temperature and precipitation projections. In this respect, the sections considered in this study do not show any substantial difference in the pavement performance when the precipitation data from the climate predictions are also considered in the climate inputs into AASHTOWare Pavement ME software.