THE SIGNIFICANCE OF DERMATOMAL SOMATOSENSORY EVOKED POTENTIALS IN THE DIAGNOSIS OF LUMBOSACRAL NERVE ROOT COMPRESSION

ＴＨＥＳＩＧＮＩＦＩＣＡＮＣＥＯＦＤＥＲＭＡＴＯＭＡＬＳＯＭＡＴＯＳＥＮＳＯＲＹＥＶＯＫＥＤＰＯＴＥＮＴＩＡＬＳＩＮＴＨＥＤＩＡＧＮＯＳＩＳＯＦＬＵＭＢＯＳＡＣＲＡＬＮＥＲＶＥＲＯＯＴＣＯＭＰＲＥＳＳＩＯＮ（李辉）（陈君长）（王坤正）（贺西京）（鱼全...     

大白鼠同神经与不同神经输入对脊髓背角神经元的会聚

实验用大白鼠。分级刺激腓肠神经和腓肠肌神经,对被激活的背角神经元进行观察,进而对皮肤、肌肉神经传入会聚神经元进行了分类,发现同一神经刺激被激活的背角神经元可分为A、A—C和C 3个类型,其中A—C型占多数(皮神经激活68%,肌神经激活50.4%)。实验中记录到125个皮,肌会聚神经元(CMCN),按对皮、肌A类和C类传入纤维的反应,分为A—A、A—AC、AC—A,AC—AC、C—C 5型,其中AC—AC和A—A型占多数(分别为46.27%和26.12%).结果提示,上述多种会聚形式,可能是皮、肌粗、细初级传入在脊髓水平对感觉传入(特别是痛觉)进行调制的基础,因此将在镇痛、痛过敏中起作用。     

CaMKⅡ在8-Br-cAMP诱发的脊髓背角LTP中的作用

目的　探讨钙钙调蛋白依赖性蛋白激酶Ⅱ(CaMKⅡ)在8 Br cAMP诱发的脊髓背角长时程增强(LTP)中的作用。方法　采用SD 大鼠, 常规细胞外记录技术记录脊髓背角腰膨大部位浅层C 纤维诱发电位。结果　①8 Br cAMP(1 mmol/L)诱发的脊髓背角LTP咬合(occlude)强直刺激诱导的LTP;②CaMKⅡ选择性抑制剂KN 93 (100μmol/L)或AIP(200μmol/L)阻断8 Br cAMP诱导的脊髓背角LTP;③蛋白质合成抑制剂茴香霉素(200μmol/L)抑制8 Br cAMP诱发的脊髓LTP。结论　CaMKⅡ参与8 Br cAMP诱导的脊髓背角C 纤维诱发的LTP;8 Br cAMP诱导的LTP与强直电刺激诱导的LTP在机制上至少存在部分相同的步骤或途径。     

EP 信号潜伏期变化的自适应相位谱估计方法

研究了诱发电位（ＥＰ）信号潜伏期变化的检测与估计问题．传统的时域平均ＥＰ信号检测方法不能跟踪潜伏期的时变特性，基于相关计算的ＥＰ信号检测方法在存在外界周期性干扰的条件下是很不可靠的．本文提出一种自适应相位谱时间延迟估计方法，用于在低信噪比和低信扰比条件下检测和估计诱发电位信号潜伏期的变化．实验和计算机模拟表明，在信噪比和信扰比均低至－５ｄＢ时，本文方法仍能有效地跟踪ＥＰ信号潜伏期的变化，给出正确的估计结果．这种方法也可以用于时实ＥＰ信号的分析和处理．     

油品衰变监测技术的研究与应用

文章阐明了油品衰变监测的内涵、技术手段,论述了油品衰变是机械设备的故障根源。列出了实施设备主动维修需解决的关键性问题,得出了研究和应用油品衰变监测技术,可以有效地实施机械设备主动维修,对设备维修制度改革具有重要意义。     

Changes in firing rate and firing pattern of midbrain dopaminergic neurons after lesioning of the dorsal raphe nucleus by 5,7-drhydroxytryptamine in adult rats

Objective To study the effect of serotonergic efferent projection of the dorsal rophe nucleus (DRN) on the activity of substantia nigro pars compacta (SNc) and ventral tegmenta area (VTA) dopaminergic neurons after lesioning of the DRN by the neurotoxin 5,7-drhydroxytryptamine (5,7-DHT) in rot. Methods The changes in the firing rote and firing pattern of SNc and VTA dopaminergic neurons were observed with extrocellular recording in control and the lesioned rats. Results The results showed that the mean firing rotes of the fast-firing dopaminergic neurons of the SNc in control and the lesioned rots were (5.34±0. 13 ) Hz (n = 23 ) and ( 7.13±0. 49 ) Hz (n=37), respectively. The mean firing rote of the fast-firing dopaminergic neurons of the SNc in the lesioned rats was significantly increased when compared to that of control rots (P<0.01), while the mean firing rote of the slow-firing dopaminergic neurons of the SNc did not change. The mean firing rotes of dopaminergic neurons of the VTA in control and the lesioned rots were (5.27±0. 38)Hz (n=35) and (3.6±0.2)Hz (n=52), respectively. Lesioning of the DRN induced a significant decrease in the mean firing rote of dopaminergic neurons of the VTA. The firing pattern of SNc and VTA dopaminergic neurons changed towards a more bursting or irrgular firing after the lesioning. Conlusion These data suggest that the serotonergic efferent projections of the DRN significantly affect the activity of SNe and VTA dopaminergic neurons.     

基于PID的高速无人机高度控制系统设计

采用传统的PID姿态控制方法实现高速无人机的高度控制,采用从内回路到外回路逐层设计的方法。运用根轨迹法对开环传递函数进行分析,确定各参数的大致取值范围。再利用时域法及频域法,在取值范围内反复比较各组参数的时域和频域响应指标,直至得出一组最佳参数值。     

重庆市褐色黏土根系固土特性的试验研究

为了解根系在增强褐色黏土抗剪强度中的作用机理,用室内直剪试验研究了根系复合土的应力—应变及强度特征,探讨了有无根系、根系布置位置、根系布置方式和复合体是否含石下的土体抗剪强度.结果表明:纯细粒土表现为脆性破坏,而根系(面积比率(RAR)为0.07％)加入后,根系复合土出现2个强度峰值表现为延性破坏;根系布置在土体位移开始区更利于固土效果;褐色黏土中散生根系固土效果优于垂直根系的固土效果,其根系复合土比无根土的黏聚力c提高了67％、内摩擦角提高了82％;土体中加入一定量D≤2cm碎石的土壤——根系复合体有利于根系固土效果.     

古石拱桥地基加固方案探讨

该文在对某地基出现不均匀沉降的古石拱桥进行详细勘查的基础上,提出了采用深层搅拌桩和树根桩对该桥地基进行加固的初步方案,并对该方案的施工要点进行了分析。     

CORRELATION OF THE MAGNETIC MOTOR EVOKED POTENTIAL TECHNIQUE WITH PATHOLOGICAL CHANGES ASSOCIATED WITH SPINAL CORD INJURY IN ADULT CATS

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