自身免疫病的生物学治疗进展

临床工作中,自身免疫病的治疗极具挑战性,传统上采用的糖皮质激素和免疫抑制剂等化学药品治疗虽然有效,但长期使用都不可避免的带来很多毒副作用。近10余年来,基于该病发病机制中不同环节的特异性生物学治疗成为热点,它们的应用使治疗过程能够终止自身免疫反应的破坏作用而又不伤害正常的免疫防御系统成为可能。     

DNA含量及S期细胞比值与肺癌生物学特性的关系

目的研究流式细胞术DNA含量及S期细胞比值(SPF)测定及其与肺癌临床病理指标的关系。方法应用流式细胞仪(FCM)对56例肺癌新鲜组织及36例非癌性病变的肺新鲜组织的DNA含量(DI)和SPF进行测定,并结合临床病理资料分析其意义。结果①肺癌病变组织DNA含量、SPF均显著高于非癌性病变组织(P<0.01)。肺癌组异倍体率78.6%,而肺非癌性病变组异倍体率5.6%,两组相比差异有显著性(P<0.01);②肺癌组织DNA含量与肺癌组织学类型和临床分期无明显关系(P>0.05);③肺癌异倍体组SPF高于二倍体组(P<0.05)。肺癌SPF与肿瘤分期、转移呈正相关关系(P<0.05);随临床分期增加,SPF均相应增加(P<0.05)。结论DNA含量改变、增殖活性的增加在肺癌组织中具有普遍意义。肺癌组织增殖活性越高,肿瘤转移的潜能越大。肺癌组织的FCM DNA含量及细胞增殖活性测定有助于进一步研究肺癌的生物学行为。     

纳米LaxSr1-xCu1-yCoyO3的制备和光电催化特性

用甘氨酸-硝酸盐燃烧法制备LaxSr1-xCu1-yCoyO3纳米晶体复合氧化物,并用XRD、SEM、EDS以及IR对纳米晶体的晶型、晶粒大小、形貌及组成进行表征,晶体粒子是球形的,粒径在17.8~43.7 nm之间,为正交和立方晶系。用活性碳为载体制备功能氧电极,采用三电极体系,测试循环伏安曲线,发现该氧电极具有双功能催化特性,但不完全可逆。利用汞灯作为激发光源,对水溶性染料进行光解实验,利用紫外-可见、红外以及人工神经网络光度法研究LaxSr1-xCui1-yCoyO3的催化性能。结果表明:LaxSr1-xCu1-yCoyO3(x=0.3,0.7;y=0.3,0.7),具有较强光催化特性,该复合氧化物催化剂对含有5种染料的废水具有高效脱色作用。     

大型曝气生物滤池污水处理厂提标改造设计

沈阳仙女河污水处理厂是采用曝气生物滤池工艺的大型污水处理厂,处理规模达40万m3/d。在其提标改造工程中,将现状二级曝气生物滤池改造成了带反硝化功能的三级生物滤池,并采用加砂沉淀池作为深度处理单元,使出水水质由《城镇污水处理厂污染物排放标准》（GB 18918—2002）的二级标准提高至一级A标准;同时通过建设应急处理系统,实现了不停产施工、不降低排放标准的预期目标。     

云南某工业园区污水处理厂工艺设计

云南某工业园区污水处理厂设计规模1.0×104m^3/d,二级处理采用倒置AAO工艺,生化池与二沉池、硝化液回流、污泥回流、剩余污泥排放等合建,具有占地面积小、工程造价低、运行维护以及管理方便等特点,三级处理采用“转盘滤池+生物快渗+紫外线消毒工艺”,设计出水水质达到《城镇污水处理厂污染物排放标准》(GB 18918—2002)一级A标准。     

Temporal stability of travelers' activity choice and home-stay duration: Some empirical evidence

This paper explores the temporal stability of activity type-choice models and models of travelers' home-stay duration. To empirically evaluate this stability, a nested logit model of activity-type choice and a proportional hazards model of home-stay duration are estimated using data from two-day travel diaries collected in the fall of 1989 and again, from the same individuals, in the fall of 1990. The results show that the models are not temporally stable over the one year time period separating the two travel-diary samples. A number of possible reasons for this instability are discussed.     

生物三相流化床处理印染废水的工程工艺理论研究

研究以生物三相流化床作为工程化反应器处理印染废水的工程工艺理论及操作特性，分别测定流化床内的气相含率，液体循环速度及体积氧传质系数，讨论它们之间的关系，明确工程化操作的条件，并经半年多的实际运行检验了所建立理论的正确性，实现了节能、高效与稳定出水的目标。     

论虚工作是单双代号网络图的实质性区别

单代号网络图与双代号网络图区别的主要形式是其符号含义的互换。由于符号含义互换带来它们之间某些时间参数计算和关键线路确定的方法不同,但是这些不同都是当双代号网络图存在虚工作时引起的。所以单双代号网络图除符号含义不同之外,其时间参数计算的实质区别取决于双代号网络图中有无虚工作。针对网络计划一实例分析了虚工作造成的实质性区别,说明了这种实质性的区别在网络计划应用中的重要性。     

大学英语教学要激发学生的学习动力

本文探讨了在大学英语教学中老师应如何激发学生的学习动力,阐述了学习动力在教学中的重要性,以及如何根据学生学习英语的情绪活动特点来激发学生学习动力,主要有四个方面的因素:注重情感因素;培养学习兴趣;满足表现欲;正确评价表现。     

Understanding the relationships between private automobile availability, overall physical activity, and travel behavior in adults

In most developed countries motorized transportation is the dominant form of travel for long and short journeys. Transport-related physical activity (TPA), however, is advocated as an appropriate transport mode for traveling short distances. The purpose of this study is to explore the associations between private automobile availability, overall physical activity levels, and TPA engagement in the adult population. A population-representative telephone survey assessed socio-demographics, private automobile availability, overall physical activity levels, and travel to place of work/study and the convenience shop with an adult sample (n = 2,000) residing in North Shore City, Auckland, New Zealand in April 2005. The majority of respondents reported unrestricted (80%) or frequent (12%) private automobile availability. After controlling for covariates, binary logistic regression analyses revealed those with no private automobile available were less likely to be classified as sufficiently active for health benefits when compared to respondents with unrestricted private automobile availability. However, this finding was based on a small minority (4%). Also, those reporting no private automobile availability were more likely to walk or cycle to place of employment and the convenience shop when compared to those with unrestricted private automobile availability. Similar to other self-report travel and physical activity survey tools, the questionnaire used potentially did not adequately capture TPA engagement. Future TPA research needs to incorporate objective measures to address this issue.