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21.
根据HPV6、11、16、18、31、33型L1ORF高度保守区的基因序列设计合成了一对HPVL1区共有引物。该引物除与上述六型有很高的同源性外还可覆盖其它已知的20多型与女性肛生殖区感染有关的HPV。用该引物及PCR技术对一组计144例活检标本进行检测,结果显示:病理确诊的尖锐湿疣、子宫颈癌及外阴癌组织、正常宫颈标本中HPVDNA序列检出率分别为100%(55/55)、70%(28/40)和13.3%(2/15)。另外,34例临床诊断而未被病理证实的尖锐湿疣HPV-DNA亦呈阳性,说明在对这类病变进行病理诊断时有必要进行病原学检测。 相似文献
22.
在国内外供应链管理研究及河北港口群煤炭业务现状调研分析的基础上,剖析现阶段港口煤炭供应链运营管理的问题。聚焦河北港口群煤炭供应链模式构建过程,梳理港口煤炭供应链管理流程,构建河北港口群供应链管理模式、物流协同模式、物流体系及物流供应链协同信息化支撑模式,解决制约港口煤炭供应链的信息共享不及时、信息流通不畅等问题。对港口煤炭供应链协同运作信息化体系进行总体框架设计,并选择典型平台建设探讨供应链协同运作信息化体系支撑实现模式,形成高效、科学、先进的河北港口群煤炭供应链管理模式。 相似文献
23.
We investigate the problem of designing an optimal annual delivery plan for Liquefied Natural Gas (LNG). This problem requires determining the long-term cargo delivery dates and the assignment of vessels to the cargoes while accommodating several constraints, including berth availability, liquefaction terminal inventory, planned maintenance, and bunkering requirements. We describe a novel mixed-integer programming formulation that captures important industry requirements and constraints with the objective of minimizing the vessel fleet size. A peculiar property of the proposed formulation is that it includes a polynomial number of variables and constraints and is, in our experience, computationally tractable for large problem instances using a commercial solver. Extensive computational runs demonstrate the efficacy of the proposed model for real instances provided by a major energy company that involve up to 118 cargoes and a 373-day planning horizon. 相似文献
24.
协同制造是一种能够实现快速响应市场的生产模式,该生产模式已经成为21世纪制造业发展的必然趋势.为了实现当前制造环境下制造资源共享与优化配置,描述了企业间协同制造的基本概念,提出了协同制造任务的分配和资源发现,分析了协同制造的策略与运行模式及战略伙伴的选择,比较了几种算法的优缺点,给出了应用实例,用遗传算法对事例进行了论证并对事例进行了优化,得出了可行性的结论. 相似文献
25.
物流的转型--供应链管理 总被引:2,自引:0,他引:2
与物流相比,供应链管理更能够给企业带来巨大的经济效益。因此,对供应链管理的进一步研究具有现实的意义。 相似文献
26.
供应链企业间的关系管理是供应链管理的重点,而价格折扣是供应链企业间最常用的关系协调机制。文中用一个有一个供应商与多个经销商的供应链,假定了四种特殊关系,即:(1)横向(经销商之间)、纵向(与供应商)不合作;(2)横向不合作,纵向合作;(3)横向合作,纵向不合作;(4)横向合作,纵向合作。针对供应链企业之间的各种关系设计不同的价格折扣方案以满足供应链企业的利益最大化;对各种关系下的价格折扣方案进行比较,得到了不同关系下价格折扣率的取值范围。 相似文献
27.
Within the literature concerned with aspects of competitiveness, innovation and strategic management of industrial clusters, the body regarding forecasting of strategic management is still nascent. This work aspires to render a contribution within the domain of strategic management forecasting, through the indicative case of European maritime clusters. For this end, a two-tier model is formulated. A quantitative strengths, weaknesses, opportunities, and threats (SWOT) methodology that derives from the fusion of a quondam situation analysis and crosstabs’ theory is generated. This leads to the utilization of the crosstab’s conditional probabilities as transition probabilities; the latter are called to compile the transition matrix of a Markov chain. Through this methodology, and the successive Markov chain’s transition matrices, strategic forecasts are extracted for a devised European maritime cluster case. This work relinquishes a novel application with respect to strategic management forecasting, that provides a dichotomy of practical interpretations and scenarios for quantitative situation analysis. Thus, it may enable effective real-time decision-making for strategic management and/or policy drafting. The situation analysis forecasting model may find applicability in a plethora of practical and theoretical cases, wherein forecasting may be desirable. It may as well pertain to an intrinsic methodology for situation analysis forecasting of maritime clusters. 相似文献
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29.
ABSTRACTThe container shipping industry is receiving growing attention in driving the performance of global supply chains. This phenomenon has accelerated supply chain integration (SCI) within the industry. Although SCI could offer numerous benefits, it is often quoted to be implemented easier in theory than in practice. The high failure rate that is associated with SCI is often not addressed in the literature. Grounded on resource-based view (RBV) theory, this paper is aimed at identifying the critical success factors (CSFs) and examining their influence on SCI and supply chain performance (SCP). Survey questionnaires were administered on 164 container shipping firms. The constructs were validated empirically using confirmatory factor analysis and were subsequently analysed using structural equation modelling. The proposed CSFs in this study are found to be positively corelated with SCI, which, in turn, is positively correlated with SCP. This paper has contributed to both theory and practice by applying RBV theory to identify the key resources and capabilities that are necessary for SCI in the container shipping industry. 相似文献
30.