THE EXPRESSION OF p16 AND CYCLIN D1 IN PROLIFERATIVE ENDOMETRIUM AND ENDOMETRIAL CARCINOMA

The development of malignanttumors is close-ly related to the abnormality of cell cycle regula-tion.Cyclin D1and p1 6are key factors that havepositive and negative effects on regulating cell cy-cle,respectively.In general,itwas considered thatthe over- expression of oncogene cyclin D1or/andinactivation of anti- oncogene p1 6contribute to themalignant transformation of cells.As has been re-viewed,the aberrant expression of cyclin D1or/andp1 6was involved in the development and progres-sion of …     

CARD/1的应用与二次开发

介绍CARD/1的基本功能及在铁路工程上的应用与二次开发成果.     

Oracle 9i在Red Hat Advanced Server下的安装

对Oracle 9i在RedHatAdvanced Server Linux上的安装过程进行了总结,着重介绍了Oracle 9i安装时对RedHat Advanced Server的要求和解决办法.     

大功率履带推土机的差速转向技术

应用运动学分析的方法,对大功率履带推土机差速转向机构的工作原理及使用特点进行了讨论与分析.由此得出转向液压马达的旋转方向决定了推土机转向的方向,转向液压马达的旋转速度决定了推土机转向半径的大小,同时说明了差速转向机构具备转向轻便、转弯半径小、不需维护与调整的优点.结果表明差速转向技术比传统的转向离合器-制动器式转向技术具有更大的优越性.     

BP神经网络和GM(1,1)灰色模型在公路客运量预测中的应用

在灰色预测的基础上,引入BP神经网络模型,建立了GM(1,1)和BP神经网络组合模型。此组合模型兼有灰色预测和BP神经网络预测的优点,模型既克服了原始数据少,数据波动性大对预测精度的影响,也增强了预测的自适应性。实例证明了组合模型的预测精度高于单独的GM(1,1)模型,可以用于公路客运量预测。     

抗H2S腐蚀的08Cr2AlMo材料应用

根据国内原油现状和对外原油依赖性的增加以及硫腐蚀的破坏性,提出对炼油设备材料的耐硫腐蚀性的必要要求。依据08Cr2AlMo钢的化学成分,分析了该种钢的性能以及应用环境,由于其合理的化学成分及先进的制造工艺,使得08Cr2AlMo钢具有良好的抗H2S腐蚀性能,最后针对08Cr2AlMo钢制造的换热器管束进行分析。实践表明:08Cr2AlMo钢管具有良好的可焊性,在含硫原油的腐蚀体系中具有抗腐蚀的作用,可广泛应用在炼油行业上。     

基于多因子关联分析的道路交通事故灰色预测模型研究

基于灰关联分析,对道路交通事故的影响因子进行预处理,建立了基于多因子关联分析的道路交通事故GM(1,N)预测模型。对哈尔滨市1994年~2004年的道路交通事故进行实例分析,预测结果表明GM(1,N))模型的预测精度高于GM(1,1)模型及多元线性回归模型。该模型克服了GM(1,1)模型对于波动性较大的非平稳数列预测精度低的缺点,该模型具有简单、有效、预测精度高的特点。GM(1,N)模型是一种动态数据处理方法,且不会出现量化分析与定性分析结果矛盾的现象,能够很好的反映交通事故的未来发展趋势。     

1,1`—二（二苯基膦）二茂铁作为双膦螯合配体性能的研究

本文研究了1,1’—二(二苯基膦)二茂铁(dppf)作为σ—供电子配体与过渡金属生成配合物的反应性能,研究结果表明,它如同双膦(diphos)螯合配体一样,不仅与中心金属之间有较强的螫合作用,可稳定低价态的过渡金属有机配合物,而且在多核金属有机配合物里又可作为桥连配体。然而,由于dppf配体里含有一个二茂铁的骨架,它与diphos配体的性能之间在某些方面又存在明显的差异。     

THE OVEREXPRESSION AND SIGNIFICANCE OF CYCLIN D1 AND P53 IN CERVICAL SQUAMOUS CELL CARCINOMAS

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Correlation between endothelia cells activation and imbalance of cytokines in pulmonary hypertension of congenital heart disease

Objective To explore the correlation between endothelia cells activation and cytokines （ET-1, NO） levels in patients with pulmonary hypertension （PH）, and to discuss their roles in the development of PH. Methods Twenty patients with simple ventricular septal defect （VSD） were chosen as controls, and 30 patients with PH were studied. Plasma levels of ET-1 and NO were measured by radioimmunoassay or colorimetric method. Before cardiopulmonary bypass was established, the specimens from right lung were fixed with formaldehyde solution, embedded with paraffin and stained by SP immunohlstochemistry. Intercellular adhesion molecule-1 （ICAM-1） expression was measured through the determination of the light density with computer imaging technology. Results Compared with that of the patients with simple VSD, the light density of ICAM-1 and plasma level of ET-1 increased in patients with PH; but plasma level of NO decreased （P〈0.05）. Positive correlation was observed between ICAM-1 and ET-1/NO （P〈0.05）. Conclusion Endothelia cells activation and imbalance of ET-1/NO might play an important role in the development of PH.