舰船尾流气泡层散射相位函数的计算与分析

利用Mie散射理论及其递推公式并结合舰船尾流气泡的测量结果,得到了舰船尾流中气泡群的散射相位函数。通过对散射相位函数的分析与讨论,得出：尾流存在时间及气泡群分布模型参数的变化对散射相位函数的影响较小,仅当小半径气泡密度增加时其后向散射强度略有减小;尾流气泡相对于海水的折射率变化是影响尾流气泡群散射相位函数的主要因素,相对折射率越大,后向散射越弱。     

周期性波动管流的压降研究

Experiments were conducted to study characteristics of flow when flow is fluctuating. The experimental results showed a phase difference between the flow rate and the pressure drop fluctuations. This phase difference between the fluctuating flow rate and pressure drop was analyzed for laminar flow. Analysis showed that the phase difference changes with the period of the flow fluctuation, the pipe radius, the density and the dynamic viscosity of the liquid. Fluctuating pipe flow was then numerically simulated. Results of the numerical simulation were compared with theoretical values and experimental results. It was shown that, when the flow rate fluctuates with time as a sine wave, the pressure drop fluctuates with the same periodicity, and there is a phase difference between them.     

惯导辅助的GPS船舶测姿系统关键技术研究

针对现有的多种周跳检测与修复、整周模糊度求解算法以及单纯GPS测姿和单纯惯导测姿的优缺点,提出了一种适合船舶姿态测定的方案。该方案结合平差原理和多普勒信息处理周跳,并对LAMBDA算法进行了改进和优化,采用多种约束信息来剔除不正确模糊度组合,最后采用基于Kalman模型进行陀螺与GPS航向角数据融合。实验结果表明,在0.497m基线条件下,航向角精度优于0.3°,俯仰角(横滚角)测量精度优于0.5°。     

影响汽车方向盘转角脉冲输入试验结果的因素

介绍了汽车系统频响函数输入的标准信号,阐述了在汽车方向盘转角脉冲输入试验中,各种因素对横摆角速度频响函数的影响。     

深圳地铁一期工程项目管理实践与思考

介绍了深圳市地铁有限公司通过加强规划及设计管理,积极推进科研工作,建立精干、高效的项目管理组织, 实行“公开、公平、公正”的工程招标,强化工程质量与安全管理,做好文明施工,以开通时间为目标的项目进度控制,及全过程的动态投资控制等一系列项目管理措施,使深圳地铁一期工程实现了如期、顺利、安全、高水平、高质量一次性全线通车的目标。     

车用电喷式汽油机9工况排放测试分析

按9工况法规对车用电喷式汽油机进行排放测量试验,对3种有害排气污染物(CO,HC,NOx)单工况和同类工况分担率进行了分析,得出各工况对整机排放的影响程度,并提出了改善该类汽油机排放水平的重点研究工况。     

设有行人专用相位的交叉口行人闯红灯行为及应对策略研究

针对主次路相交并设置行人专用相位的交叉口行人闯红灯的普遍现象,提出整个交叉口行人专用相位与几个进口行人可用相位相结合的信号配时方案,通过仿真验证得出,该方法不仅有效的降低了行人闯红灯率,减少了行人的等待时间,而且机动车的延误没有明显的增加。这种配时方案为解决我们城市主次路相交等道路宽度差距较大的交叉口中的行人闯红灯现象提供一个较好的思路。     

尿毒症apoE基因敲除小鼠主动脉动脉粥样硬化的病变特征

目的 观察尿毒症apoE-/-小鼠主动脉粥样硬化(As)病变特征及MMP-9的表达.方法 以apoE-/-小鼠为研究对象,通过2步外科手术法建立尿毒症模型,对照组行假手术.造模后检测肾功能,判断造模是否成功.造模后10周,检测血清MMP-9浓度;主动脉根部切片油红O染色计算斑块相对面积,天狼星红染色计算斑块内胶原含量,α-肌动蛋白、MAC3免疫组化染色检测斑块内SMC及巨噬细胞的含量;RT-PCR法检测主动脉MMP-9 mRNA的表达.结果 造模后肾功能检测显示造模成功.尿毒症组与对照组相比:主动脉根部As斑块相对面积提高、斑块内胶原含量减少、SMC成分减少、巨噬细胞含量增加,血清MMP-9浓度及主动脉MMP-9 mRNA的表达提高.结论 尿毒症apoE-/-小鼠主动脉加速发展的As伴随着斑块的稳定性降低.     

宁夏回族高脂血症患者CYP2C9*3、MSA2756G基因多态性的研究

目的 研究高脂血症治疗的药物相关基因CYP2C9*3、甲硫氨酸合成酶(MSA2756G)在宁夏回族高脂血症患者中的分布及其与高脂血症的关系.方法 通过扩增引进限制性酶切位点(ACRS)和应用聚合酶链式反应-限制性片段长度多态性(PCR-RFLP)技术对高脂血症患者进行基因型分析.结果 180名宁夏回族高脂血症患者中,CYP2C9*3等位基因频率为3.33%,突变频率男性(3.05%)高于女性(0.28%),差异有显著性(P<0.01),而与健康对照组(3.00%)比较,差异无显著性(P>0.05);MSA2756G等位基因频率为15.83%,显著高于健康对照组(10.25%)(P<0.05),未发现性别差异.结论 宁夏回族人群携带CYP2C9*3基因型的男性患高脂血症风险更大;MSA2756G可能是高脂血症的危险因子.     

Association between the -1562 C/T polymorphism in the MMP-9 promoter and phenotype of esophageal squamous cell carcinoma in northern Chinese population

Objective To conduct a case-control study on the association of the nucleotide polymorphisms in the promoter region of the matrix metalloproteinase-9 (MMP-9) gene with phenotype of esophageal cancer. Methods All subjects were unrelated residents in northern regions of China. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was used to determine the MMP-9 genotypes. Results The overall distribution of genotypes in the patients was not different from that in the controls (OR=0.77, 95% CI=0.45-1.34; P=0.36). There were no significant differences between the patients and the control subjects in terms of the distributions of sex and age, smoking status, alcohol dependence, pickled diet status, or history of environmental exposure. The patients were further examined with stratifications by age, sex, grade, depth of tumor invasion, lymphatic invasion, venous invasion and TNM staging. The results showed no pronounced association among the stratifications. Conclusion There is no significant association between the MMP-9 single nucleotide polymorphism genotypes and phenotype of esophageal cancer.