EFFECTS OF DIPSACUS ASPER AND VITAMIN E ON THE SS NEURONS IN THE HIPPOCAMPAL FORMATION OF RAT MODELS OF ALZHEIMER‘S DISEASE

Ａｌｚｈｅｉｍｅｒ’ｓｄｉｓｅａｓｅ (ＡＤ)ｉｓｔｈｅｍｏｓｔｃｏｍｍｏｎｄｅｍｅｎｔｉａｉｎｔｈｅｓｅｎｉｏｒ ,ａｎｄｔｈｅｒｅｉｓｎｏｃｕｒｅｏｒｅｆｆｅｃ ｔｉｖｅｔｒｅａｔｍｅｎｔ .ＡｌｔｈｏｕｇｈｔｈｅｅｔｉｏｌｏｇｙｏｆＡｌｚｈｅｉ ｍｅｒ’ｓｄｉｓｅａｓｅｉｓｎｏｔｆｕｌｌｙｕｎｄｅｒｓｔｏｏｄ ,ａｃｃｕｍｕｌａｔｉｎｇｅｖｉｄｅｎｃｅｄｅｍｏｎｓｔｒａｔｅｓｔｈａｔｂｏｔｈｔｈｅｃｏｎｃｅｎｔｒａｔｉｏｎｏｆｔｈｅｓｏｍａｔｏｓｔａｔｉｎ (ＳＳ)ａｎｄｔｈｅＳＳｎｅｕｒｏｎｓｉｎｔｈ…     

基于Pro/E二次开发的圆柱齿轮设计CAD系统

阐述了基于Pro／E的圆柱齿轮设计CAD系统的开发方法，该方法在Visual C 6．0环境下利用C语言缟写程序接口，可实现齿轮的优化设计及参数化造型．实践证明，该系统设计结果正确，具有一定的工程价值．     

汉语编程在MapX二次开发中的应用

交通地理信息系统因具有强大的信息服务和管理功能,越来越受到人们的重视。MapX作为GIS设计中一个常用的功能组件．其当前的主要编程环境是英文,这对于英文程度不高的汉语软件开发者来说无疑是个羁绊。因此,通过实例详细说明在易语言汉语编程开发环境下如何利用MapX开发GIS软件的方法,对于该组件的进一步推广应用具有一定的意义。     

通过INMARSAT- A/B/M/MINI-M接入INTERNET

ＩＮＴＥＲＮＥＴ是目前世界上最大的计算机互联网络,它是美国正在建设中的“信息高速公路”的支柱网络之一,也是一个初具规模的全球性信息网络。ＩＮＴＥＲＮＥＴ是一个巨大的信息资源,它容许全球千百万人相互通信,共享资源。现在,Ｅ－ＭＡＬＬ和ＩＮＴＥＲＮＥＴ被广泛看作全球性商业运营的一个重要工具,作为全球商业系统一部分的船舶,近来也开始越来越多地使用这一先进的工具。本文介绍通过卫星船站接入ＩＮＴＥＲＮＥＴ的方法及操作步骤。     

渐开线圆柱齿轮减速器三维参数化设计系统的研究

主要通过 PRO/E 建模和基于 Visual C 和 PRO/TOOLKIT 的编程,介绍少齿数渐开线圆柱直齿 轮减速器的三维参数化设计的一种途径,其中详细介绍 PRO/E 基于特征、面向加工、自下而上尺寸关系等建模理 念和建模技巧,以及数据库管理技术在系统实现中的应用。实践证明,在减速器产品设计过程中,利用三维参数化 设计技术可显著提高设计开发效率。     

浅议安全监理如何在拆除延安东路高架过程中发挥的监督作用

近年来,市政基础设施建设在飞速发展,城市中可用于市政建设的空间将越来越紧张。如何在不影响周边环境和交通的前提下完成工程,对原有结构部分进行拆除和新建,尤其是在上海外滩"亚洲第一弯"拆除工程中,既要按时完成又要确保安全拆除万无一失,发挥安全监理的监督作用。该文对此作了一些有益的探讨,可供参考。     

神水泉大桥动力特性及地震作用分析

结合神水泉大桥的工程设计实例,采用大型有限元分析程序Midas Civil,选取空间梁单元建立动力计算模型,研究了桩土共同作用边界约束条件下的动力特性.采用反应谱法对该桥进行了E1地震作用分析,讨论了在CQC振型组合方法情况下结构地震响应的最大值,同时验算了E1地震作用下相关构件强度.     

基于机器视觉的农产品自动分选机机构设计

介绍了用于分选农产品的自动分选机的设计,包括机械结构的总体设计和主要机械部件的设计选型,最后采用PRO/E对分选机进行三维设计.     

表皮生长因子受体Ⅲ型变异体（EGFRvⅢ）多克隆抗体的制备及特异性

为了制备针对EGFRvⅢ的特异性多克隆抗体,在实验中利用耦联了血蓝蛋白的EGFRvⅢ特异性的PEP3合成短肽进行动物免疫,制备抗血清;构建了pET30a／E33XI原核表达载体,表达和纯化了融合蛋白His-E33（EGFRvⅢ的部分胞外区）;以此融合蛋白作为抗原制备了抗体纯化柱,通过柱上纯化的方法从抗血清中提取针对EGFRvⅢ的特异性抗体．利用U87、U251、HeLa和HEK-293细胞进行免疫组化实验来检验抗体的特异性．     

Observations of the Fawn Trough Current over the Kerguelen Plateau from instrumented elephant seals

Due to its great meridional extent and relatively shallow depths, the Kerguelen Plateau constitutes a major barrier to the eastward flowing Antarctic Circumpolar Current in the Indian sector of the Southern Ocean. While most of the Antarctic Circumpolar Current transport is deflected north of the Kerguelen Islands, the remainder ( 50 Sv, 1 Sv = 10⁶ m³ s^− 1) must pass south of the islands, most probably through the Fawn and Princess Elizabeth Troughs. However, the paucity of finely resolved quasi-synoptic hydrographic data in this remote and infrequently sampled area has limited the progress in our knowledge of the regional circulation. Since 2004, a new approach using elephant seals from the Kerguelen Islands as autonomous oceanographic profilers has provided new information on the hydrography over the Kerguelen Plateau, covering the entire Antarctic Zone between the Polar Front and Antarctica, with a mean along-track resolution of about 25 km. These finely resolved bio-logged data revealed details of a strong northeastward current found across the Fawn Trough (sill depth: 2600 m; 56°S, 78°E). This so-called Fawn Trough Current transports cold Antarctic waters found mostly south of the Elan Bank, between the Ice Limit (58°S) and the Antarctic Divergence (64°S) in the eastern Enderby Basin, toward the Australian–Antarctic Basin. Our analysis also demonstrates that the Deep Western Boundary Current, which carries cold Antarctic water along the eastern flank of the southern Kerguelen Plateau collides with Fawn Trough Current at the outlet of the Fawn Trough sill. In other words, the Fawn Trough constitutes a veritable bottleneck, channelling the quasi-totality of the Antarctic Circumpolar flow found south of the Polar Front. Thanks to the unprecedented fine resolution of seal-borne data, a branch of flow centered at the Winter Water isotherm of 1 °C is also revealed along the northern escarpment of the Elan Bank, and then along the southern edge of Heard Island. Further analysis of different supplementary data reveals a complex circulation pattern in the entire Enderby Basin, with several distinctive branches of flow being strongly controlled by prominent topographic features such as the Southwest Indian Ridge, Conrad Rise, Elan Bank, and Kerguelen Plateau. This newly emerged frontal structure refines considerably previous large-scale circulation schematics of the area.