《国际海运危险货物规则》40-20修正案主要修订内容介绍

在介绍《国际海运危险货物规则》(IMDG规则)40-20版修正案的修订脉络基础上,从危险货物分类、一览表及特殊规定等4个方面分析了修正案的主要修订内容,并根据修订情况提出相应的措施建议。     

基于FPGA的里程轮信号优选算法设计

文中通过对里程信号产生机理进行分析,提出了一种基于FPGA架构的里程优选算法,给出了实现算法的硬件架构图,并设计相应硬件电路和模拟实验。结果表明:该算法可以对3个里程轮脉冲信号进行优选采集,当里程轮处于超速或者停转状态时也能输出正确的脉冲信号。     

Reconfigurable Communication Processor： A New Approach for Network Processor

As the traditional RISC ASIC/ASSP approach for network processor design can not meet the today‘s requirements, this paper described an alternate approach, Reconfigurable Processing Architecture, to boost the performance to ASIC level while reserve the programmability of the traditional RISC based system. This paper covers both the hardware architecture and the software development environment architecture.     

Study of the mechanism on the apoptosis induced in Human leukemia cell line K562 by the combination of indole-3-acetic acid and horseradish peroxidase

Objective To investigate the mechanisms of apoptosis induced in Human leukemia cell line K562 by the combination of indole-3-acetic acid and horseradish peroxidase. Methods Human leukemia cell line K562 were exposed to indole-3-acetic acid （IAA） at 20, 40, 60, 80 or 100 mol/L and horseradish peroxidase（HRP） at 1.2 g/mL for varying times. MTT assay was applied to detect the cell proliferation. Flow cytometry was performed to detect the arrest of cell cycle. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling （TUNEL） assay was used to measure apoptosis. 2, 7-dichlorofluorescin diacetate （DCFH-DA） uptake was measured to determine free radical by confocal microscope. Content of malondiadehyde （MDA） and activity of superoxide dismutase （SOD） were measured by biochemical methods. Results IAA/HRP initiated growth inhibition of K562 cells in a dose- and time-dependent manner. Flow cytometry revealed that cell cycle arrested at G1/G0 after 24 hours treatment. After 72 hours treatment, apoptotic rate of 100 mol/L IAA group increased to 43.9 %, which was 5 times that of control（P〈0.01）. Content of MDA and activity of SOD increased respectively in treatments compared with control. Meanwhile, IAA/HRP stimulated the formation of free radical, which was increased by IAA concentration-dependently. Conclusion The combination of IAAand HRP can inhibit the growth of Human leukemia cell line K562 in vitro by inducing apoptosis which is associated with the increase of free radical. The combination of IAA and HRP might be a promising chemopreventive and chemotherapeutic agent against human leukemia.     

K3V型柱塞泵的结构、控制原理及维修

对广泛应用于大宇挖掘机上的K3V型轴向变量柱塞泵的结构及控制原理进行了论述，分析了常见故障的原因，给出了常见故障的排除方法及易损件的维修标准。     

K-ras基因点突变的反义寡脱氧核苷酸对人胰腺癌靶基因表达的抑制作用

目的　观察针对于胰腺癌K ras基因点突变的反义寡核苷酸对靶基因表达的抑制作用。方法　脂质体将人工合成的针对于K ras基因第 12位密码子点突变的反义寡核苷酸转染体外培养的人胰腺癌细胞株PC 2 ,用免疫组化和原位杂交技术检测靶基因的表达。结果　转染 4 8h后 ,反义寡核苷酸作用组胰腺癌细胞株PC 2的ras蛋白和K rasmRNA的表达程度较正义组和对照组均明显降低 (P <0 .0 5 )。结论　针对于K ras基因点突变的反义寡核苷酸作用于体外培养的胰腺癌细胞 ,对靶基因的表达有明显的抑制作用     

萘乙酸抑制K562细胞增殖作用的初步研究

目的研究萘乙酸(NAA)对K562细胞增殖的抑制作用。方法应用MTT法、细胞计数法、流式细胞术、分裂指数分析、tunnel法以及姊妹染色单体交换(sister chromatid exchange,SCE)和微核制备,对NAA处理的K562细胞进行细胞增殖、细胞周期、凋亡以及染色体损伤检测。结果与对照组相比,NAA可以有效抑制K562细胞的生长,并将细胞阻滞在G1期,降低细胞分裂指数,促进细胞凋亡,提高K562细胞SCE频率以及微核形成率。结论NAA具有抑制K562细胞增殖的作用。     

EFFECTS OF DIPSACUS ASPER AND VITAMIN E ON THE SS NEURONS IN THE HIPPOCAMPAL FORMATION OF RAT MODELS OF ALZHEIMER‘S DISEASE

Ａｌｚｈｅｉｍｅｒ’ｓｄｉｓｅａｓｅ (ＡＤ)ｉｓｔｈｅｍｏｓｔｃｏｍｍｏｎｄｅｍｅｎｔｉａｉｎｔｈｅｓｅｎｉｏｒ ,ａｎｄｔｈｅｒｅｉｓｎｏｃｕｒｅｏｒｅｆｆｅｃ ｔｉｖｅｔｒｅａｔｍｅｎｔ .ＡｌｔｈｏｕｇｈｔｈｅｅｔｉｏｌｏｇｙｏｆＡｌｚｈｅｉ ｍｅｒ’ｓｄｉｓｅａｓｅｉｓｎｏｔｆｕｌｌｙｕｎｄｅｒｓｔｏｏｄ ,ａｃｃｕｍｕｌａｔｉｎｇｅｖｉｄｅｎｃｅｄｅｍｏｎｓｔｒａｔｅｓｔｈａｔｂｏｔｈｔｈｅｃｏｎｃｅｎｔｒａｔｉｏｎｏｆｔｈｅｓｏｍａｔｏｓｔａｔｉｎ (ＳＳ)ａｎｄｔｈｅＳＳｎｅｕｒｏｎｓｉｎｔｈ…     

城市轨道交通轨道检测系统关键设备研制及应用

为了探索一种可应用于城市轨道交通运营列车组的轨道检测方法,基于ARM微处理器和现场可编程门阵列(FPGA)设计搭载式轨道检测系统。分析了搭载式轨道检测系统的总体架构和数据处理印刷电路板的设计过程,并对系统的核心部件嵌入式微处理板卡进行了重点探讨,该板卡可实现小型化、低功率、多样化数据集成。对该系统进行了动态试验验证,试验结果说明该系统在准确性、重复性、一致性等方面都满足标准要求。搭载式轨道检测系统可安装于城市轨道交通运营列车上进行实时检测,大大提高了轨道检测的效率和实时性,可有效指导线路养护维修工作,且该系统不必占用专门检测车资源,具有良好的经济效益。     

基于Kalman滤波和变时间窗测频的转速测量FPGA实现

利用信号与噪声状态模型的Kalman滤波,对频率进行无偏估计,适合对机车运行速度的精确测量.利用变时间窗采集脉冲信号的方法克服了常规算法中刷新时间和测量精度不稳定的缺点,同时也保证了对不同频率的测量精度.通过基于FPGA平台的算法设计与仿真,表明了上述方法对机车转速测量的实时有效性和准确性.