大跨度悬索桥嵌岩桩基础设计探讨

结合实际工程及相关规范,探讨了跨江津几江大跨度悬索桥嵌岩桩基础设计应注意的问题,并提供了一种较合理m法来计算岩石地基系数比例系数m的思路,对类似工程有参考借鉴作用。     

Induction of animal model of Graves' disease in BALB/c mice

Objective To construct an animal model of Graves' disease (GD) by immunizing BALB/c mice with hM12 cells co-expressing major histocompatibility complex (MHC) class Ⅱ molecules and human thyrotropin receptor (TSHR) molecules. Methods BALB/c mice in experimental group (H-2d) were immunized with hM12 cells Intraper-itoncally every 2 weeks for six times, while mice in control group were immunized with M12 cells. Five weeks later, the thyroids were histologically examined, and serum samples were tested for thyroid-stimulating antibodies (TSAb) and thyroid hormone levels. Results One BALB/c mouse in experimental group developed Graves'-like disease. Total T4 and T3 levels in this mouse were above the upper limit of normal, TSAb activity was displayed in its serum. The thyroid histologically showed the features of thyroid hyperactivity including thyrocyte hypercellularity and colloid absorption.None of control mice developed Graves'-like disease. Conclusion An animal model with some characteristics of human Graves' disease was successfully induced and the model will facilitate studies aimed directly at understanding the patho-genesis of autoimmunity in Graves' disease.     

M／M／1排队系统嵌入Markov链瞬态解的格路径算法

在定义了生灭过程状态转移的单格与升降格和降升格的基础上,证明了M／M／1排队系统{X（t）t≥0}的嵌入Markov链{X（n）,l≥0}的转移概率弱收敛于系统的瞬态解,并利用随机游动的格路径算法求出了该链的转移概率P（i,j,n）的显式算法表达式,从而达到确定M／M／1排队系统{x（t）f≥0}瞬态解的转移概率的目的．     

洞口段浅埋偏压隧道新型防护结构及其简化计算方法

针对现有洞口段浅埋偏压隧道支护结构在施工时所存在的容易坍塌、整体位移过大等问题,在充分发挥抗滑桩、锚索和管棚优点的基础上,利用交叉施工和分时注浆方法,提出一种洞口段浅埋偏压隧道新型防护结构。建立地形偏压下防护结构的简化分析模型,并利用M法对防护结构在地形偏压下的内力和位移进行求解;然后利用变形协调条件对结构的内力和位移进行修正,最终得出该新型结构在地形和施工偏压联合作用下的受力和变形状况。结合算例,对新型防护结构的内力和位移分布规律进行分析,并将计算结果与ADINA模拟结果进行对比,验证了简化计算方法的可靠性,为该新型结构的分析与设计提供了理论基础和依据。     

诺尔斯成人教学论及其对继续教育课程开发的启示

诺尔斯成人教学论是关于成人教和学的科学,它以学习过程为切入点,明确指出了成人学习的特征。该教学论为继续教育课程开发带来了很多启示,为成人继续教育的课程改革提供了新的视角。     

用面向对象设计方法开发车号员信息处理系统

面向对象的方法(00M)是结构化程序设计的延伸,采用OOM方法进行编程,可以产生一个清晰而又容易扩展及维护的程序。本文结合一个已经投入使用的车号员信息处理系统说明来用OOM进行系统设计的实现方法。     

The egg morphology of 7 Acartiidae species: a preliminary survey of the ootaxonomy of calanoids

This is the first contribution to acartiid taxonomy based on egg morphology. Eggs laid under laboratory conditions by maintaining female specimens of Acartia adriatica, A. clausi, A. italica, A. margalefi, A. tonsa, Paracartia latisetosa and Pteriacartia josephinae were studied by S.E.M. Most species produced eggs with intraspecific variation in their external morphology. In spite of such variation, however, it was possible to separate three species groups.     

综合物探技术在石膏岩岩溶路基探测中的应用

岩溶易引起路基坍塌和下沉,是严重危害铁路运输安全的路基病害。本文采用探地雷达和多道瞬态面波相结合的综合地球物理探测方法,对青藏铁路K1333+000—K1333+660段石膏岩路基进行探测。结果表明,该段路基存在多处岩溶病害及岩溶引起的次级病害。后期的钻孔结果验证了本次测试的准确性。采用探地雷达和多道瞬态面波综合物探技术,能够较为全面、高效地检测路基中可能存在的隐患,可为及时采取加固处理措施提供依据。     

聚氨酯固化道床的力学性能试验研究

聚氨酯固化道床是介于传统碎石道床和无砟轨道整体道床之间的一种新型结构。本文介绍了聚氨酯固化道床的国内外现状;通过聚氨酯固化道床围压试件的疲劳荷载、冻融试验、实尺模型疲劳试验和现场加载车测试试验,研究聚氨酯固化道床的弹性、抗累积变形、荷载传递规律及轨排阻力等力学性能。试验结果表明:聚氨酯固化道床具有良好弹性保持能力和抗累积变形能力,和普通碎石道床相比,具有更好的抵抗横向荷载能力,同时验证了聚氨酯固化道床结构设计断面的合理性。     

渗流作用下盾构隧道施工过程中地表沉降预测研究

应用数值分析法研究了广州地铁一区间隧道盾构施工过程中渗流对地表沉降的影响。基于Peck横向地表沉降计算理论,将渗流产生的孔隙水压按隧道上覆土的重力归一化处理,且以理论计算所得沉降为标准,对考虑渗流作用的地表沉降进行归一化,提出了耦合渗流作用时最大地表沉降估算方法。与实测及理论计算结果对比分析表明,本文所建立的计算模型和地表沉降修正计算方法合理、有效。