Effects of erigeron breviscapus （Vant.） Hand-Mazz pretreatment on pathology and oxyradical level following spinal cord ischemia-reperfusion injury in rabbits

Objective To investigate the effects of erigeron breviscapus (Vant.) Hand-Mazz (erigeron breviscapus) pretreatment on pathology and oxyradical level in the spinal cord after ischemia-reperfusion (I/R) injury in rabbits. Methods A total of 40 New Zealand white rabbits were randomly divided into three groups: sham-operation group with 10 rabbits treated with only abdominal aorta exposure without occlusion, control group with 15 rabbits that underwent ischemia for 50 minutes and treated with matched saline, and experimental group with 15 rabbits that underwent ischemia for 50 minutes and treated with erigeron breviscapus (9mg/kg) injection before ischemia. Malondialdehyde (MDA) level and superoxide dismutase (SOD) activity in the spinal cord were examined at 6 and 24 hours after I/R, respectively. The morphological changes and the number of the spinal cord anterior horn motor neurons were observed and counted under the light microscope and electron microscope, respectively. Results The level of MDA was markedly decreased and SOD activity was increased in the experimental group compared with those in the control group (P<0.01). Compared with that in the control group, the number of motor neurons in the experimental group significantly increased at 24h after I/R (P<0.01) and the morphous of the motor neurons improved. Conclusion Erigeron breviscapus can reduce oxyradical production and the apoptosis of nerve cells, and protect nerve tissue structure and function after spinal cord I/R.     

Correlation of expression of ER, PR and c-erbB-2 with ultrasonographic features in invasive ductal cancer of breast

Objective To analyze the relationship of the expression level of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2, c-erbB-2) of breast invasive ductal carcinoma (IDC) with ultrasonographic characteristics. Methods Totally 104 patients with IDCs confirmed pathologically were involved in this study. ER, PR and c-erbB-2 expression in the IDC specimens was determined by immunohistochemical staining technique. The correlation between the ultrasonographic features and the positive expression of ER, PR or c-erbB-2 was analyzed. Results The positive expression rate of ER and PR in the group with tumor spiculation sign and posterior acoustic attenuation was higher than that in the group without. The positive expression rate of ER differed significantly (P<0.05) while that of PR did not (P>0.05). The over-expression rate of c-erbB-2 in the group of microcalcification, sufficient blood flow and axillary lymph node metastasis was higher than that in the group of non-microcalcification, deficient blood flow or without axillary lymph node metastasis (P<0.05). The expression of ER, PR and c-erbB-2 was not related to the size of tumor (P>0.05). Conclusion The expression of ER and c-erbB-2 is closely related to the ultrasonographic characteristics of IDC, which may, to some extent, reflect the expression level of ER and c-erbB-2.     

江苏交通运输业与地区经济发展的灰色关联分析：1999-2008

文章采用灰色关联法对1999-2008年江苏交通运输业与地区经济发展的关联程度进行了实证测定,研究发现这10年里江苏交通运输业货运周转量指标的关联系数变化相对平稳,运输船舶净载量、民用车辆拥有量和固定资产投资额等指标的关联系数在2005年后均快速下降。提出了进一步提高江苏交通货运周转量、加大对运输船舶净载量、民用车辆拥有量和旅客周转量指标的关注度、动态变动地区交通运输业发展战略等措施,以促进江苏交通运输业与地区经济的协调发展。     

基于指数标度的层次分析法在桥梁评定中的应用

针对层次分析法中1-9标度存在的问题,根据心理学上韦伯-费希纳定律,引入指数标度及对应的随机一致性检验指标,应用到桥梁技术状况评定中。以钢管混凝土拱桥为例,依据相同的重要性关系评语,分别以指数标度和1-9标度构造判断矩阵,计算出各个构件权重系数。计算结果表明:指数标度能较为准确地反映出钢管混凝土拱桥构件之间的重要性关系。     

隧道软弱下卧地基注浆加固试验

注浆法是提高软土地基承载力和控制其压缩沉降的传统加固方法,由于其过程不可控性与加固效果的不确定性,在应用于加固运营地铁隧道下卧土时,须考虑加固过程的扰动及长期效果。通过现场试验,研究注浆加固的工艺参数对饱和软土扰动和加固效果的影响,以获得安全合理的精细化注浆工艺参数,对处理软土地铁隧道长期沉降问题具有现实意义。     

大孔隙水泥稳定碎石(CTPB)排水基层性能的室内试验研究

通过室内试验,研究了用于路面排水结构层的大孔隙水泥稳定碎石(CTPB)的材料要求、配合比设计、压实成型方法、强度特性和抗压回弹模量等。得出了以下结论:集料颗粒的最大粒径选择应以排水层的厚度及该层的结构强度要求为基础;水泥含量、C/A及孔隙率Va是影响CTPB排水基层混合料抗压强度最显著的因素;施工中,CTPB排水基层混合料的成型应采用静压成型,不宜采用振动压实;要求集料具有较低的压碎值。     

考虑端部位移的连续配筋路面温度应力解析解

针对现行《公路水泥混凝土路面设计规范》推荐的连续配筋混凝土路面(CRCP)温度应力计算方法不能充分反映CRCP实际受力条件的弊端,提出了考虑连续配筋混凝土路面(CRCP)板端部实际位移情况的计算思路。推导了降温和温度梯度作用下,连续配筋混凝土路面(CRCP)温度应力的通用解析解。利用该解析解,可以计算连续配筋混凝土路面(CRCP)任一点由温度变化引起的应力、位移值,通过与有限元解对比表明,提出的解析解准确、合理,符合工程实际。     

基于HiL实时联合仿真自动变速器控制系统TCU快速开发研究

建立了自动变速器模型,并集成于车辆发动机实时仿真平台Labcar-PT系统,构成了接近于实车的虚拟车辆TCU开发环境.在此基础上利用Bypass技术实现了TCU软件快速开发,并将TCU控制策略应用到实际车辆进行了道路试验.自动变速器模型实时仿真结果和实车测试结果对比表明,二者吻合性较好,基于此快速开发系统开发的TCU控制策略有效.     

一种基于HCCI模式的参比油简化机制及其验证

引入数值模拟精度的定义,采用两组分参比油模拟了HCCI发动机点火过程,对Youngchul Ra和Rolf D. Reitz提出的正庚烷与异辛烷氧化过程进行敏感性分析及优化处理,对H.J.Curran的详细反应机理进行数值验证,在验证范围(初始温度530~600 K,当量比0.3~0.8,压缩比12.5~28)的大部分区域内,优化后简化模型的数值模拟结果满足一级精度。利用HCCI发动机的三维CFD耦合化学动力学模型,模拟缸内燃烧流动过程,得到缸内压力及中间产物和燃烧相位的关系,计算结果与试验结果吻合较好。     

线管式NTP反应器降低柴油机PM排放的研究

设计了一种线管式低温等离子体反应器,对该反应器的工作特性进行了试验研究及理论分析,并采用该反应器进行了降低柴油机排气PM的台架试验。研究结果表明,线管式低温等离子体反应器存在两种不同的放电形式,介质阻挡电晕放电和介质阻挡丝状放电,其放电形貌与工作特性显著不同。两种放电形式均可降低柴油机PM排放;介质阻挡丝状放电较介质阻挡电晕放电对PM的处理效果更好,能量利用效率也更高。当反应器放电形式为介质阻挡电晕放电时,反应器中同时存在对PM氧化分解的化学过程和对PM荷电捕集的物理过程。